Maryam Sotoudeh Anvari; Mohammad Ali Boroumand; Elham Amelimojarad; Marjaneh Nosrati; Neda Moradi; Hamidreza Goodarzynejad
Volume 8, Issue 4 , October 2013, , Pages 209-218
Abstract
Background and Objectives: Bacterial bloodstream infections (BSIs) and surgical site infections (SSIs) are among the most common nosocomial infections with high mortality and morbidity. We aimed to evaluate the frequency of various species among BSIs and SSIs at Tehran Heart Center, Tehran, Iran. Methods: ...
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Background and Objectives: Bacterial bloodstream infections (BSIs) and surgical site infections (SSIs) are among the most common nosocomial infections with high mortality and morbidity. We aimed to evaluate the frequency of various species among BSIs and SSIs at Tehran Heart Center, Tehran, Iran. Methods: Patients with localized or systemic infections that became evident 48 hours or more after hospitalization were included. Data were prospectively collected in 4 intensive care units (ICUs), 5 cardiac care units (CCUs), 7 post-CCUs, and 5 surgical wards during two consecutive years in 2008 and 2009. Approximately 18414 coronary angiography and 7393 open-heart surgeries were done within this period. Antimicrobial susceptibility testing was performed by the Kirby–Bauer disk diffusion method, in accordance with the Clinical and Laboratory Standards Institute (CLSI) guidelines. Results: Among 212 detected patients with SSI and/or BSI in the year 2008, 138 had hospital acquired infection (HAI) and 74 had non–HAI while these figures for 2009 was 165/270 and 105/270, respectively. Staphylococcus aureus (21.5%) and Entrobacter spp. (16.5%) were two most common pathogens responsible for hospital acquired BSIs while S. aureus (20.6%) and S. epidermidis (20.6%) were corresponding isolates responsible for community acquired BSIs. Staphylococcus aureus (53.3%) and Escherichia coli (11.0%) were the two most common pathogens responsible for hospital acquired SSIs in the year 2008, while S. aureus (49.0%) and S. epidermidis (11.0%) were the most frequently reported hospital acquired SSIs in 2009. Conclusions: Making rational decisions about hospital infection control plans may reduce infection rates for bacteria with antimicrobial resistance.
Mohammad Rahbar; Massoud Hajia; Mona Mohammadzadeh
Volume 7, Issue 1 , January 2012, , Pages 32-37
Abstract
Background and Objective: Early diagnosis of Streptococcus agalactiae remains difficult, since symptoms are very nonspecific. Its frequency has not been completely investigated in urinary tract pathogen of pregnant ant and non pregnant women in Iran. The aim of this study was determining the frequency ...
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Background and Objective: Early diagnosis of Streptococcus agalactiae remains difficult, since symptoms are very nonspecific. Its frequency has not been completely investigated in urinary tract pathogen of pregnant ant and non pregnant women in Iran. The aim of this study was determining the frequency of Group B Streptococci in female patients.
Materials and Methods: A Total of 11800 urine specimens were received from female out-patients admitted during June till December 2010. Group B Streptococci isolates were confirmed by typical colony morphology, and identified by differential tests as well as by the growth characteristics in chromoagar. A provisional urinary tract infection diagnosis was defined by the presence of single group B Streptococci (>10 CFU/liter) with at least one of urinary tract infection symptom. Susceptibility testing was carried out by disk diffusion method.
Results: Of all specimens 498 specimens (4.22%) yielded significant bacteriuria caused by group B Streptococci. The mean age of these patients were 26.6 + 19.37. Pregnant patients were 3.82% and the rest were non-pregnant. Antibiotic susceptibility test revealed that vancomycin, clindamycin and cefazolin had the lowest and penicillin showed the highest resistant rate.
Conclusion: Pattern onantibiotic susceptibility test showed high resistant rate to some antibiotic that made it difficult for pregnant patients, although its frequency was low. It was not possible to compare the antibiotic susceptibility pattern of pregnant women with non-pregnant because of the low number of pregnant women registered in this study.
