Abazar Akbarzadeh Pasha; Sepideh Siadati; Shahriar Shafaei; Vakili Sadeghi
Volume 9, Issue 2 , April 2014, , Pages 152-155
Abstract
Primary myeloid sacrom (MS) is a rare tumor and even more rare in multiple organs with no evidence of bone marrow involvement. This report describes an unusual case of a 19-year-old male presenting scrotal MS with a history of subconjunctival MS, 5 months ago. Bone marrow biopsies showed no evidence ...
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Primary myeloid sacrom (MS) is a rare tumor and even more rare in multiple organs with no evidence of bone marrow involvement. This report describes an unusual case of a 19-year-old male presenting scrotal MS with a history of subconjunctival MS, 5 months ago. Bone marrow biopsies showed no evidence of acute leukemia. Despite radiotherapy for first involvement and chemotherapy for second presentation, his condition deteriorated and he unfortunately died. This case is presented here to remind an unusual presentation of MS and to address that the pathologist should bear in mind the possibility of MS when making the differential diagnosis of unusual lymphoma or undifferentiated nonhematological tumors.
Moslem Bahadori; Katayoun Gohari Moghaddam; Saeed erakhshani; Mohammad Vafaie
Volume 1, Issue 2 , April 2006, , Pages 81-86
Abstract
Background and Objectives: The etiology, pathophysiology, nomenclature and clinical manifes-tation of solitary rectal ulcer syndrome (SRUS) is poorly understood. Aim: To examine the pathology of mucosal changes and clinical features of this syndrome. Materials and Methods: The mucosal biopsies of 19 ...
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Background and Objectives: The etiology, pathophysiology, nomenclature and clinical manifes-tation of solitary rectal ulcer syndrome (SRUS) is poorly understood. Aim: To examine the pathology of mucosal changes and clinical features of this syndrome. Materials and Methods: The mucosal biopsies of 19 patients with clinical evidence of solitary rectal ulcer as been reviewed in accordance with their clinical complaints and endoscopic findings within three years. Results: SRUS has been seen in both sexes (11 male and 8 female) at the age ranging from 12 to 72 years (mean 29 years). The main clinical complaints were rectal bleeding, mucorrhea and perianal pain. The major rectoscopic findings were ulceration, erythema of mucosal surface, congestion and polypoid pattern. The significant pathologic features were mucosal architectural distortion, very superficial and irregular mucosal ulceration, fibrosis of lamina propria and thickening of the muscularis mucosa with splaying of its fibers and extension of muscularis fibers between the mucosal crypts. Conclusion: Although SRUS is rare but it can be confused clinically with other similar diseases such as inflammatory bowel disease,cloagenic carcinoma and other malignancies. It must be looked in differential diagnoses of pelvic disorders since it is well recognized on rectoscopic and morphologic basis.