Pulmonary Pathology
Bahram Nikkhoo; Karim Naseri; Ramyar Rahimi Darehbagh; Mehrdad Habiby; Bahar Moasses-Ghafari
Abstract
BackgroundCovid-19 in known to present with acute respiratory distress syndrome pathological manifestations. Studies have shown that patients with Covid-19 can develope diffuse alveolar damage, acute bronchopneumonia, necrotic bronchiolitis, and viral pneumonia.Case PresentationIn this study, we investigate ...
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BackgroundCovid-19 in known to present with acute respiratory distress syndrome pathological manifestations. Studies have shown that patients with Covid-19 can develope diffuse alveolar damage, acute bronchopneumonia, necrotic bronchiolitis, and viral pneumonia.Case PresentationIn this study, we investigate 11 cases. Needle necropsies of 11 patients, hospitalized at Tohid and Kowsar hospitals of Kurdistan University of medical Sciences, with a positive antemortem SARS-CoV-2 (COVID-19) real time PCR test, were fixated within 3 hours after death in the negative-pressure isolation morgue. The participants included 6 men (54%) and 5 women (46%) with mean age of 73.82 ± 10.58 (52–86) years old. The average hospitalization was 14.27 ± 15.72 days. The results showed an interstitial lymphocytic pneumonitis in most of the cases, with severities ranging from mild to moderate and severe in some cases. In 7 cases, Anthracosis and in one case, anthracosis with fibrosis was evident. Hyaline membrane was reported in two patients. In one case, a severe interstitial lymphocytic pneumonia with intra-alveolar exudate with organization, lithiasis, bronchiolitis pattern (BOOP) along with intra-alveolar hemorrhage and mild fibrosis was seen.ConclusionAs a result, it is suggested to keep an eye on these pathologies in managing severe case of COVID-19 infection.
Nahid Kazemzadeh; Alireza Kadkhodaei; Babak Soltani; Siamak Soltani; Sahar Rismantab Sani
Volume 9, Issue 3 , July 2014, , Pages 181-186
Abstract
Background & Objectives: Respiratory, central nervous system, and skin complications of mustard gas toxicity have previously been studied; however, the liver and kidney side effects due to this intoxication have not been fully noted. We aimed to evaluate the frequency of liver, kidney and lung lesions ...
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Background & Objectives: Respiratory, central nervous system, and skin complications of mustard gas toxicity have previously been studied; however, the liver and kidney side effects due to this intoxication have not been fully noted. We aimed to evaluate the frequency of liver, kidney and lung lesions in mustard gas-exposed Iranian veterans who had been exposed to the toxin almost 2 decades before.
Methods: A total of 100 veteran bodies underwent autopsy by at least two forensic medicine specialists. The liver, kidney and lung specimens were sent for pathological examination and their lesions, severity of the lesions, and the relation between the type/severity of the lesions and the time elapsed since their appearance were studied.
Results: A total of 83%, 63%, and 62% of the veterans had lung, liver, and kidney pathologies. The most common pathologies included liver steatosis, interstitial fibrosis of the kidney, and lung atelectasis.
Conclusion: Liver and kidney pathologies are far more common than what is considered in the mustard gas-exposed veterans. These pathologies are often accompanied by very severe lung complications.
Maryam Kadivar; Pegah Babaheidarian; Ali Zare Mirzae; Mohammadreza Fakhraie
Volume 8, Issue 2 , April 2013, , Pages 115-118
Abstract
There are few reported cases of endobronchial metastasis of pheochromocytoma literature. We present here a 56-year old woman who underwent left lower lobectomy of lung, following pneumonia with unresolved chest radiographs. Computed tomography showed a lobulated soft tissue mass, measuring, 38×27 ...
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There are few reported cases of endobronchial metastasis of pheochromocytoma literature. We present here a 56-year old woman who underwent left lower lobectomy of lung, following pneumonia with unresolved chest radiographs. Computed tomography showed a lobulated soft tissue mass, measuring, 38×27 mm, at the perivascular space of anterior mediastinum. The resected specimen, showed lobulated tumor arranged in nesting pattern within arcuate vascular network. Immunohistochemistry showed intense positive staining of epitheloid cell (chief cells) for chromogranin and synaptophysin which were negative for cytokeratin. Sustentacular cells were strongly positive for S-100. Although very rare, physicians should keep in mind the possibility of endobronchial metastasis in patients with a history of pheochromocytoma.