Volume 17 (2022)
Volume 16 (2021)
Volume 15 (2020)
Volume 14 (2019)
Volume 13 (2018)
Volume 12 (2017)
Volume 11 (2016)
Volume 10 (2015)
Volume 9 (2014)
Volume 8 (2013)
Volume 7 (2012)
Volume 6 (2011)
Volume 5 (2010)
Volume 4 (2009)
Volume 3 (2008)
Volume 2 (2007)
Volume 1 (2006)
Evaluating of the Effects of Sub-MIC Concentrations of Gentamicin on Biofilm Formation in Clinical Isolates of Pseudomonas aeruginosa

Zahra Yousefpour; Fateme Davarzani; Parviz Owlia

Volume 16, Issue 4 , August 2021, , Pages 403-410


  Background & Objective: The ability of Pseudomonas aeruginosa to form biofilm has an important role in establishment of chronic phase of infections. Biofilm formation can be affected by antibiotics sub-MIC concentrations. The principal aim of the present study was to evaluate the effect of gentamicin ...  Read More

The role of Gene Mutations (gyrA, parC) in Resistance to Ciprofloxacin in Clinical Isolates of Pseudomonas Aeruginosa

Zoheir Heshmatipour; Nasibeh Arabameri; Shima Eftekhar Ardebili; Zeinab Jafari Bidhendi

Volume 16, Issue 4 , August 2021, , Pages 426-432


  Background & Objective: Pseudomonas aeruginosa is an opportunistic pathogen and one of the most common causes of nosocomial infections. This bacterium's antibiotic resistance to the common fluoroquinolone antibiotics, especially ciprofloxacin, is due to mutations in the gyrA and parC genes. This ...  Read More

Prevalence of blaOxacillinase-23 and blaOxacillinase-24/40 carbapenemase genes in Pseudomonas aeruginosa isolated from patients with nosocomial and non-nosocomial infections in West of Iran

Samaneh Rouhi; Rashid Ramazanzadeh

Volume 13, Issue 3 , July 2018, , Pages 348-356

  Background and Objective: Pseudomonas aeruginosa (P. aeruginosa) causes serious nosocomial and non-nosocomial infections. blaOxacillinases (OXA)-23 and blaOXA24/40 provide resistance to carbapenem antibiotics. The aim of this study was assessment of blaOXA-23 and blaOXA-24/40 in P. aeruginosa isolated ...  Read More

Prevalence of Clinically Isolated Metallo-beta-lactamase-producing Pseudomonas aeruginosa, Coding Genes, and Possible Risk Factors in Iran

Abdolmajid Ghasemian; Kobra Salimian Rizi; Hassan Rajabi Vardanjani; Farshad Nojoomi

Volume 13, Issue 1 , January 2018, , Pages 1-9


  Background & Objective: The spread of carbapenem-resistant Pseudomonas aeruginosa is a global concern. Metallo-beta-lactamase (MBL) enzymes cause extensive drug resistance among Gram-negative bacteria. The current study aimed at determining the prevalence of MBL-producing P. aeruginosa in Iran. Methods: ...  Read More

blaVIM and blaIMP Genes Detection in Isolates of Carbapenem Resistant P. aeruginosa of Hospitalized Patients in Two Hospitals in Iran

Behrang Kazeminezhad; Arezoo Bostanmanesh Rad; Atoosa Gharib; Sara Zahedifard

Volume 12, Issue 4 , December 2017, , Pages 392-396


  Background & objective: Beta-lactam antibiotics resistance specifically Imipenem and Meropenem, the last choices of treatment, causes fatal events in patients with P.aeruginosa infection. The aim of this study was to detect the VIM and IMP of metallo-beta-lactamase genes in 103 isolates of P. aeruginosa ...  Read More

Conserved OprF as a Selective Immunogen Against Pseudomonas aeruginosa

Ehsan Kazemi Moghaddam; Parviz Owlia; Abolfazl Jahangiri; Iraj Rasooli; Mohammad Reza Rahbar; Marjan Aghajani

Volume 12, Issue 2 , April 2017, , Pages 165-170


  Background & Objectives: Due to the importance of Pseudomonas aeruginosa in severe inpatient infections and high mortality, the need for an efficient vaccine against these bacteria is increasing. In this regard, the general outer membrane porin of the most problematic microorganism P. aeruginosa, ...  Read More

Relation between Resistance to Antipseudomonal β-Lactams and ampC and mexC Genes of Pseudomonas aeruginosa

Fatemeh Rezaei; Horieh Saderi; Shahram Boroumandi; Soghrat Faghihzadeh

Volume 11, Issue 1 , January 2016, , Pages 47-53

  Background: In order to select a better antibiotic choice for treatment of Pseudomonas aeruginosa infections, this study was conducted to determine the frequency of resistance to some antipseudomonal β-lactams in P. aeruginosa isolates from patients in Tehran, Iran. In addition, the relation between ...  Read More

Detection of Multidrug Resistant (MDR) and Extremely Drug Resistant (XDR) P. Aeruginosa Isolated from Patients in Tehran, Iran

Horieh Saderi; Parviz Owlia

Volume 10, Issue 4 , October 2015, , Pages 265-271


  Background: This study was done to detect multidrug resistant (MDR) and extremely drug resistant (XDR) of Pseudomonas aeruginosa among strains isolated from patients in Tehran, Iran, due to importance of these phenotypes in treatment of human infections. Methods: Eighty eightP. aeruginosa were isolated ...  Read More

In Vitro Bactericidal Activity of Encapsulated Amikacin in Liposome

Mohsen Mirzaee; Parviz Owlia; Mohammad Reza Mehrabi; Amir Gharib

Volume 4, Issue 4 , September 2009, , Pages 151-156

  Background and Objectives:  The most common problems limiting the medical use of aminoglycosides have been the nephro- and oto-toxicities as well as the increasing bacterial resistance. Encapsulation of drugs into liposomes enhances their efficacy while reducing their toxicities. The aim of this ...  Read More

Phenotypic Detection Of Metallo-beta-lactamase Producing Pseudomonas aeruginosa Strains Isolated From Burned Patients

Parviz Owlia; Horieh Saderi; Zohreh Karimi; Seyed Mohammad Bagher Akhavi Rad; Mohammad Ali Bahar

Volume 3, Issue 1 , January 2008, , Pages 20-25

    Background and Objective: Metallo-beta-lactamase (MBL)-mediated resistance is an emerging threat in hospital isolates of Pseudomonas aeruginosa. There is not enough information from Iran regarding the prevalence and the screening methods for such enzymes. The present study was undertaken to detect ...  Read More

Antimicrobial Susceptibility Pattern of Clinical Isolates of Pseudomonas Aeruginosa in a Pediatric Hospital

Sara Jam; Duman Sabzevari; Arezoo Aghakhani; Ali Eslamifar; Mohammad Banifazl; Amitis Ramezani

Volume 2, Issue 4 , September 2007, , Pages 144-148

  Background and Objective: Pseudomonas aeruginosa has become a frequent cause of nosocomial infections, particularly in intensive care units (ICUs). Many reports have documented high rates of resistance in this species to commonly-used broad-spectrum antibiotics. The aim of this study was to assess the ...  Read More

A Novel High-Performance Liquid Chromatography Method for Detection of Alginate in Pseudomonas aeruginosa

Parviz Owlia; Effat Souri; Qurban Behzadian-Nejad

Volume 2, Issue 3 , June 2007, , Pages 104-108

  Background and Objective: The opportunistic pathogen Pseudomonas aeruginosa secrets a capsule-like polysaccharide called alginate which is important for evasion of host defenses, especially in patients with suppressed immunity. Method of alginate determination has an important role in the study of microbial ...  Read More

Drug resistance of isolated strains of Pseudomonas Aeruginosa from burn wound infections to selected antibiotics and disinfectants

Parviz Owlia; Horieh Saderi; Sadegh Mansouri; Sirus Salemi; Hossein Ameli

Volume 1, Issue 2 , April 2006, , Pages 61-64

  Background and Objectives: Infection is the most common problem following burn injury. Selection and dissemination of intrinsic and acquired resistance mechanisms increase the probability of burn wound colonization by resistant species including Pseudomonas aeruginosa. Multi-drug resistant Pseudomonas ...  Read More