Zohreh Yousefi; Shohreh Saeed; Nourieh Sharifi
Volume 5, Issue 2 , March 2010, , Pages 105-108
Abstract
Placental site trophoblastic tumor (PSTT) is the rare variant of gestational trophoblastic diseases (GTD), which differs histologically and immunologically from GTD. Diagnosis of PSTT is often difficult and delayed. In most cases, diagnosis is not possible until the surgery is performed. The ...
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Placental site trophoblastic tumor (PSTT) is the rare variant of gestational trophoblastic diseases (GTD), which differs histologically and immunologically from GTD. Diagnosis of PSTT is often difficult and delayed. In most cases, diagnosis is not possible until the surgery is performed. The most therapeutic choice is hysterectomy and it is usually successful. Here we report two cases of PSTT.
Zohreh Yousefi; Shohreh Saeed; Nourieh Sharifi; Maryam Bahreini
Volume 4, Issue 1 , January 2009, , Pages 9-12
Abstract
Background and Objectives: Presence of steroid hormone receptors (estrogen and progesterone) in the tumor tissues of various organs correlates with response to therapy and prognosis. Since their role in ovarian cancer is still controversial, in this study we investigated the expression and prognostic ...
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Background and Objectives: Presence of steroid hormone receptors (estrogen and progesterone) in the tumor tissues of various organs correlates with response to therapy and prognosis. Since their role in ovarian cancer is still controversial, in this study we investigated the expression and prognostic value of the estrogen receptor (ER) and progesterone receptors (PR) in ovarian papillary serous carcinoma (PSC). Material and Methods: In this retrospective study we determined the expression of tissue receptors including tissue samples from 36 patients with stage III ovarian PSC by Immunohistochemistry method. Then ER and PR expression correlated with clinicopathological parameters and possible prognostic impact on ovarian PSC were investigated. Results: The correlation between age and survey of patients with ovarian PSC and expression of steroid receptor was not significant. Although correlation between severity of expression of PR and mortality rate was not meaningful, the relationship between severity of ER expression and mortality rate was significant (P=0.02) Conclusion: The determination of steroid receptor status may offer additional prognostic information in ovarian carcinoma (PSC).
