Hedieh Moradi-Tabriz; Alireza Abdollahi; Baharak Mehdipour; Saeideh Mahfoozi
Volume 5, Issue 4 , September 2010, , Pages 194-198
Abstract
Background and Objectives: A. baumannii is a cause of various infections with significant morbidity and mortality in the world. The aim of this study was to determine infection rate and antimicrobial susceptibility of A. baumannii in an Iranian tertiary care Hospital.
Materials and Methods:
This ...
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Background and Objectives: A. baumannii is a cause of various infections with significant morbidity and mortality in the world. The aim of this study was to determine infection rate and antimicrobial susceptibility of A. baumannii in an Iranian tertiary care Hospital.
Materials and Methods:
This study was performed on 166 positive blood cultures for A. baumannii, received from different wards of Imam Hospitals complex in Tehran, during two years. Disk diffusion method was used to survey several antibiotics resistance. Data were analyzed by spss software, chi square test.
Results: A. baumannii was resistant to imipenem (26.9%), gentamicine (32.2%), carbenicillin (36.4%), cephotaxime(41.7%), ampicillin (66.7%), amikacine (69.4%), ciprofloxacin (74.3%), cotrimoxazol (86.3%),piperacillin (91%), Ceftriaxone (92.5%), cefixime (99.2%), amoxiclave (100%), cefepime(100%), ceftazidime (100%). ICUs (50.6%) and Pediatrics Wards (2.4%) were the most and the least frequent wards in which A. baumannii were isolated.
Conclusions: Due to antibiotic resistance pattern change among A. baumannii and its consequences, it is recommended to control infection associated risk factors as well as further researches aiming identification of different of patterns in resistance and sensitivity to antibiotic.
Hedieh Moradi Tabriz; Alireza Abdollahi; Saeideh Mahfoozi
Volume 5, Issue 3 , June 2010, , Pages 143-149
Abstract
Background and Objectives: Blood stream infections cause significant morbidity and mortality in the world. In this study, we aimed at describing the organisms responsible for septicemia in 2006-2007 and their antimicrobial susceptibility that might lead to proper selection of antimicrobial agents ...
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Background and Objectives: Blood stream infections cause significant morbidity and mortality in the world. In this study, we aimed at describing the organisms responsible for septicemia in 2006-2007 and their antimicrobial susceptibility that might lead to proper selection of antimicrobial agents in hospitalized patients with suspected sepsis. Materials and Methods: Microbiology reports of 1753 blood specimens collected from inpatients of a referral hospital in Iran were retrospectively reviewed. Specimen culture, bacterial identification, and disk diffusion susceptibility testing were performed according to The Clinical and Laboratory Standards Institute guidelines. Data were analyzed by SPSS, X² Test and the fisher exact Test. Results: Coagulase-negative Staphylococci accounted for most isolated bacteria (24.61%), in both genders. The second and third most frequent isolated bacteria in adults were staphylococcus aureus and Stenotrophomonas maltophilia, and in children were Klebsiella pneumoniae and S. aureus. Among the all Gram – positive cocci, vancomycin was the most effective agent. The most effective antibiotic varied among the Gram-Negative isolates, for example 95.65% of S. maltophilia were susceptible to co-Trimoxazole, and amikacin were suitable antibiotic in 85.29% of E. coli. Conclusion: As the degree of antibiotic resistance rate for blood stream pathogens is alarming, it is mandatory to monitor the susceptibility of these isolates in order to avoid inappropriate use of antibiotics in hospital wards