Arghya Bandyopadhyay; Krishnendu Mondal; Mimi Gangopadhyay; Mamata Sinha Guha Mallick; Amita Giri
Volume 8, Issue 4 , October 2013, , Pages 277-280
Abstract
Histoid Leprosy (HL) is a rare variant of Lepromatous Leprosy, occurring in long-standing cases, mostly in a background of acquired drug resistance. Patients usually present with sudden onset multiple nodules and plaques, most often involving the skin and subcutaneous tissue of trunk and lower limbs. ...
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Histoid Leprosy (HL) is a rare variant of Lepromatous Leprosy, occurring in long-standing cases, mostly in a background of acquired drug resistance. Patients usually present with sudden onset multiple nodules and plaques, most often involving the skin and subcutaneous tissue of trunk and lower limbs. Here we report an unusual case of de novo (without any history of prior anti-leprotic therapy) HL, arising as multiple nodules in the face. The histopathology of the lesion showed collection of spindled macrophages in the dermis, oriented in a storiform-like pattern. A possibility of HL was considered and the diagnosis was confirmed by performing a modified ZN stain (Wade-Fite stain) on the biopsy material, which revealed the presence of acid-fast bacilli (AFB) with a bacillary index of 6. Then the patient was put on multibacillary multi-drug chemotherapy and was thereby cured.
Indranil Chakrabarti; Anuradha De; Amita Giri
Volume 6, Issue 3 , June 2011, , Pages 147-152
Abstract
Primitive neuroectodermal tumor (PNET) of kidney is an extremely rare renal neoplasm with only about fifty reported cases in literature. Presumably,of neural crest origin, these tumors behave aggressively and ...
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Primitive neuroectodermal tumor (PNET) of kidney is an extremely rare renal neoplasm with only about fifty reported cases in literature. Presumably,of neural crest origin, these tumors behave aggressively and carry a poor prognosis. We report a case of 22-year old female patient complaining of left loin pain with recurrent hematuria for last 3 months. On clinical examination, the abdomen was soft and no palpable mass was felt. She underwent ultrasonography and com puted tomography, which revealed a left renal mass. A left radical nephrectomy was performed. Histopathological examination of the nephrectomy specimen showed features of primitive neu roectodermal tumor arising from left kidney, which was confirmed by immunohistochemistry (IHC). The patient was treated with post-nephrectomy chemotherapy and was symptom-free at six-month follow-up.