Maryam Sotoudeh Anvari; Mohammad Ali Boroumand; Elham Amelimojarad; Marjaneh Nosrati; Neda Moradi; Hamidreza Goodarzynejad
Volume 8, Issue 4 , October 2013, , Pages 209-218
Abstract
Background and Objectives: Bacterial bloodstream infections (BSIs) and surgical site infections (SSIs) are among the most common nosocomial infections with high mortality and morbidity. We aimed to evaluate the frequency of various species among BSIs and SSIs at Tehran Heart Center, Tehran, Iran. Methods: ...
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Background and Objectives: Bacterial bloodstream infections (BSIs) and surgical site infections (SSIs) are among the most common nosocomial infections with high mortality and morbidity. We aimed to evaluate the frequency of various species among BSIs and SSIs at Tehran Heart Center, Tehran, Iran. Methods: Patients with localized or systemic infections that became evident 48 hours or more after hospitalization were included. Data were prospectively collected in 4 intensive care units (ICUs), 5 cardiac care units (CCUs), 7 post-CCUs, and 5 surgical wards during two consecutive years in 2008 and 2009. Approximately 18414 coronary angiography and 7393 open-heart surgeries were done within this period. Antimicrobial susceptibility testing was performed by the Kirby–Bauer disk diffusion method, in accordance with the Clinical and Laboratory Standards Institute (CLSI) guidelines. Results: Among 212 detected patients with SSI and/or BSI in the year 2008, 138 had hospital acquired infection (HAI) and 74 had non–HAI while these figures for 2009 was 165/270 and 105/270, respectively. Staphylococcus aureus (21.5%) and Entrobacter spp. (16.5%) were two most common pathogens responsible for hospital acquired BSIs while S. aureus (20.6%) and S. epidermidis (20.6%) were corresponding isolates responsible for community acquired BSIs. Staphylococcus aureus (53.3%) and Escherichia coli (11.0%) were the two most common pathogens responsible for hospital acquired SSIs in the year 2008, while S. aureus (49.0%) and S. epidermidis (11.0%) were the most frequently reported hospital acquired SSIs in 2009. Conclusions: Making rational decisions about hospital infection control plans may reduce infection rates for bacteria with antimicrobial resistance.
Maryam Sotoudeh Anvari; Mohammad Ali Boroumand; Mahmood Sheikhfathollahi; Leila Pourgholi; Hamidreza Goodarzynejad
Volume 7, Issue 2 , April 2012, , Pages 92-100
Abstract
Background and Objectives: The association between metabolic syndrome (MetS) and hyperuricemia has been formerly studied mostly in healthy people in western countries. We tried to examine the relationship betweenhyperuricemia and MetS in an Iranian population undergoing coronary angiography.
Materials ...
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Background and Objectives: The association between metabolic syndrome (MetS) and hyperuricemia has been formerly studied mostly in healthy people in western countries. We tried to examine the relationship betweenhyperuricemia and MetS in an Iranian population undergoing coronary angiography.
Materials and Methods: From March 2008 to September 2008, we studied 465 patients (260 men, 55.9%) undergoing elective coronary angiography due to symptoms related to coronary artery disease. The MetS was defined according to the adapted Adult Treatment Panel III (ATP-III A), and hyperuricemia was defined as serum uric acid concentrations ≥ 7.0 mg/dl in men and ≥ 6.0 mg/dl in women. For the statistical analysis, the statistical software SPSS version 13.0 and the statistical package SAS version 9.1 were applied
Results: The mean age of the study population was 59.66 ± 10.04, ranging from 31 to 85 years. Hyperuricemia was detected in 231 (49.7%) of total population, in 126 (54.5%) of men, and in 105 (45.5%) of women. In the multivariable adjusted model, subjects with MetS and subjects with 5 components of the MetS compared to those without any components of the MetS, had 1.56-fold and 4.19-fold increased odds of hyperuricemia, respectively. Hyperuricemia was significantly associated with elevated BP and low level of HDL-cholesterolbut not with other components of MetS.
Conclusions: Our study demonstrated that hyperuricemia was strongly associated with the prevalence of MetS according to adapted ATP III guidelines in an Iranian sample of patients undergoing coronary angiography.
