Masomeh Bayani; Sepideh Siadati; Mahmoud Hajiahmadi; Afshin Khani; Navid Naemi
Volume 9, Issue 3 , July 2014, , Pages 187-192
Abstract
Background & Objectives: Hepatitis B is one of the major health problems in the world. Health care workers (HCWs) are at high risk of acquiring hepatitis B virus. The aim of this study was to evaluate the prevalence of HBV infection and the immune response to HBV vaccine among the HCWs in Babol, ...
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Background & Objectives: Hepatitis B is one of the major health problems in the world. Health care workers (HCWs) are at high risk of acquiring hepatitis B virus. The aim of this study was to evaluate the prevalence of HBV infection and the immune response to HBV vaccine among the HCWs in Babol, northern Iran. Methods: This study was accomplished on 527 HCWs and administrative staff working at Rohani Hospital, Babol, northern Iran from 2011 to 2012. HBs- Ag, HBc- Ab and HBs- Ab were measured by ELISA method. All susceptible staff vaccinated with recombinant hepatitis B vaccine (Pasteur Institute of Iran) and HBs - Ab titer was evaluated 3 months after the last dose. Results: Anti-HBc was positive in 32 (6.1%) and HBs-Ag in 4 (0.75%) of the participants. The HBV exposure in HCWs was four times greater than the administrative staff (6.65% vs. 1.63%). There was significant association between HBV exposure and occupation and also educational level (P < 0.001), however, this association was not found with age and gender. Seroconversion was seen in 211 (91.7%) of 230 participants who received three-dose series of hepatitis B vaccine. The seroconversion is significantly decreasing by the increase of age (P < 0.001), however, no significant association was seen with age and gender. Conclusion: Considering high HBV infection exposure in HCWs, it is mandatory to ensure vaccination program and postvaccination evaluation along with education and safe work environment preparation.
Nasser Ghaemian; Sepideh Siadati; Novin Nikbakhsh; Mohaddeseh Mirzapour; Hanieh Askari; Samaneh Asgari
Volume 8, Issue 4 , October 2013, , Pages 241-246
Abstract
Background and Objectives:Breast cancer is the most common cancer among women worldwide. Fine needle aspiration biopsy (FNAB) is one of the methods of breast biopsy which is fast, easy and cost effective. The aim of this study was to evaluate the concordance rate between pathologic results of sonography ...
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Background and Objectives:Breast cancer is the most common cancer among women worldwide. Fine needle aspiration biopsy (FNAB) is one of the methods of breast biopsy which is fast, easy and cost effective. The aim of this study was to evaluate the concordance rate between pathologic results of sonography or stereotaxy guided FNAB and guided core needle biopsy (CNB) in the evaluation of breast lesions.
Materials & Methods: During December 2010 until March 2011, 36 female patients with 37 breast lesions referred to FNAB and CNB with the guide of sonography in 35 lesions and with the guide of stereotaxy in 2 lesions. The kappa statistic used to calculate the concordance coefficient.
Results: The concordance rate between guided – FNAB and guided – CNB was 93% with using kappa coefficient. In 5 patients, subjected to breast surgery, malignancy was reported as well as in guided-FNAB or guided-CNB.
Conclusion: Because of high concordance between these two techniques in the assessment of breast lesions, guided FNAB is recommended in the first step. Guided-CNB can be reserved for lesions with insufficient pathology results by guided-FNAB.