Document Type : Case Reports
Authors
Dept. of Pathology, Shalamar Institute of Health Sciences, Lahore, Pakistan
Abstract
Congenital methemoglobinemia is a rare cause of cyanosis. We report a case of a girl, 17 years old with peripheral cyanosis and normal cardio-pulmonary system. She was diagnosed as a case of methemoglobinemia based on findings of polycythemia and HbM band on hemoglobin electrophoresis. We emphasize the importance of this rare entity in the differential diagnosis of cyanosis.
Keywords
- Conway R, Browne P, O'Connell P. An unusual cause of methemoglobinemia. Ir Med J 2009;102(6):184.
- Miller DR. Hemoglobinopathies in children. Massachusetts: PSG Publishing;1980.
- Ewenczyk C, Leroux A, Roubergue A, Laugel V, Afenjar A, Saudubray JM, et al. Recessive hereditary methaemoglobinaemia, type II: delineation of the clinical spectrum. Brain 2008;131(Pt 3):760-1.
- Da-Silva SS, Sajan IS, Underwood JP, III. Congenital methemoglobinemia: a rare cause of cyanosis in the newborn--a case report. Pediatrics 2003;112(2):e158-e161.
- Jamal A. Hereditary methemoglobinemia. J Coll Physicians Surg Pak 2006 Feb;16(2):157-9.
- Hamirani YS, Franklin W, Grifka RG, Stainback RF. Methemoglobinemia in a young man. Tex Heart Inst J 2008;35(1):76-7.
- Mandel S. Methemoglobinemia following neonatal circumcision. JAMA 1989 Feb 3;261(5):702.
- Pierce JM, Nielsen MS. Acute acquired methemoglobinemia after amyl nitrite poisoning. BMJ 1989 Jun 10;298(6687):1566.
- Rieder HU, Frei FJ, Zbinden AM, Thomson DA. Pulse oximetry in methemoglobinemia. Failure to detect low oxygen saturation. Anesthesia 1989 Apr;44(4):326-7.
- Watcha MF, Connor MT, Hing AV. Pulse oximetry in methemoglobinemia. Am J Dis Child 1989;143(7):845-7.
- Howard MR, Hamilton PJ. Hematology. 1st ed. Edinburgh: Churchill Livingstone; 1997.
- AbdulRehmankhan FM, Shah SKA. Methemoglobinemia. J Postgraduate Med Inst 1990; 1:174-77.
- Nusrat M, Moiz B, Nasir A, Rasool HM. An insight into the suspected HbA2' cases detected by high performance liquid chromatography in Pakistan. BMC Res Notes 2011 Apr 5;4:103.:103.
)