Document Type : Letters to the Editor
Authors
Department of Oral and Maxillofacial Pathology, NIMS Dental College, Jaipur, India
Abstract
Dear Editor-in-Chief
Myxoid tumors of oral cavity encompass a broad spectrum of lesions, primarily neoplastic.(1) The significant variations in the biological behaviour; ranging from completely harmless to malignant neoplasm they require an accurate histopathological diagnosis to ensure a proper treatment. (2) Because of the considerable overlapping between the clinical and histopathological features, this group of tumors often produce a diagnostic difficulty to the clinicians and oral pathologists.(3) An exhaustive review of the literature reveals that there is no approved classification of myxoid tumors of oral cavity. A simple working classification of myxoid tumors is proposed here.
Keywords
Main Subjects
Dear Editor-in-Chief
Myxoid tumors of the oral cavity encompass a broad spectrum of lesions, primarily neoplastic (1). Significant variations in the biological behavior ranging from completely harmless to malignant neoplasm require an accurate histopathological diagnosis to ensure a proper treatment (2). A considerable overlapexists between clinical and histopathological features of these group of tumors, which often produces a diagnostic difficulty to clinicians and oral pathologists (3). There is no approved working classification for myxoid tumors of the oral cavity in the literature. A simple working classification of myxoid tumors is proposed here (Table 1)
Table 1. A simple working classification for myxoid tumors of oral cavity
|
S NO |
CATEGORY |
TUMORS |
|
1 |
Adipose tissue tumors
|
Myxolipoma Myxiliposarcoma
|
|
2 |
Neural tumors
|
Myxoid neurofibroma Neurothakeoma Malignant peripheral nerve sheath tumor
|
|
3 |
Fibroblastic tumors
|
Myxofibroma Nodular fasciitis Myxofibrosarcoma
|
|
4 |
Chondroblastic tumors
|
Ectomesenchymal chondromyxoid tumor Myxoid chondrosarcoma
|
|
5 |
Muscle tumors
|
Myxoid leiomyosarcoma
|
|
6 |
Odontogenic tumors
|
Odontogenic myxoma |
|
7 |
Miscellaneous
|
Soft tissue myxoma Ossifying fibromyxoid tumor Malignant ossifying fibromyxoid tumor
|
This classification is based on the predominance of the areas of myxoid degeneration in histopathology of the tumors of oral cavity. This classification includes adipose, neural, fibroblastic, chondroblastic, muscle, odontogenic and miscellaneous tumors. This classification wouldprovide a better insight into the histopathology of myxoid tumors of oral cavity and wouldbe useful for oral pathologists and cytopathologists.
- Graadt van Roggen JF, Hogendoorn PCW, Fletcher CDM. Myxoidtumours of soft tissue. Histopathology 1999;35:291
- Za´mecnı´k M. Vascular myxolipoma (angiomyxolipoma) of subcutaneous tissue. Histopathol. 1999; 34(2):180–1.
- FletcherCDM, UnniKK, MertensF (eds.). World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. Lyon: IARC Press; 2002
)