Gorham’s Disease of the Maxilla and Mandible With Distinctive Cone Beam Computerized Tomographic Features

Document Type: Case Reports

Authors

1 Dept. of Oral Medicine & Radiology, Haldia Institute of Dental Sciences and Research, Haldia, West Bengal, India

2 Dept. of Dentistry, Murshidabad Medical College and Hospital, Berhampore, West Bengal, India

Abstract

Gorham’s disease is a rare and atypical disorder epitomized by progressive osteolysis of bone with eventual total disappearance of bone. The etiology is poorly understood with variable clinical presentation. Most times it is initially misdiagnosed as temporomandibular joint dysfunction, periodontal disease or odontogenic tumors clinically and radiographically in routine dental practice. Radiographic examination, such as Cone Beam Computerized Tomography (CBCT) play a vital role in diagnosing such disorder resulting in disappearance of the involved bone entirely, which is a definitive distinguishing feature of this condition. Regarding the rarity of the condition, the current study presents a case of Gorham’s disease with distinctive clinical, radiological, and histological, features involving maxilla and mandible.

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1. R. Dominguez, T. L. Washowich. Gorham's disease or vanishing bone disease: Plain film, CT, and MRI findings of two cases. Pediatr Radiol.1994;24(5):316-8.

2. Patel DV. Gorham’s Disease or Massive Osteolysis. Clin Med Res. 2005;3(2):65-74.

3. Raghuveer HP, Jayalekshmy R. Gorham’s massive osteolysis of the mandible – a progressive radiographic presentation. Dentomaxillofac Radiol. 2009;38(5):292–5.

4. Saify FY, Gosavi SR. Gorham's disease: A diagnostic challenge. J Oral Maxillofac Pathol.2014;18(3):411-4.

5. Nikolaou VS, Chytas D, Korres D, Efstathopoulos N. Vanishing bone disease (Gorham-Stout syndrome): A review of a rare entity. World J Orthop 2014;5(5):694-8.

6. Kothari P. Gorham Disease an Enigma. Webmed Central Dentistry 2012;3(1):WMC002898.

7. Kiran DN, Anupama A. Vanishing Bone Disease: A Review. J Oral Maxillofac Surg 2011;69(1):199-203.

8. Nagaveni NB, Radhika NB, Umashankara KV, Satisha TS. Vanishing (Disappearing) Bone Disease in children – A review. J Clin Exp Dent. 2011;3(4):e328-35.

9. Patrick JH. Massive osteolysis complicated by chylothorax successfully treated by pleurodesis. J Bone Joint Surg Br. 1976;58(3):347-9.

10. Gul SK, Oruc AF, Gedik D, Gul HL, Aksu A, Mayadagli A. Gorham’s Disease that Gave Response to Radiotherapy. Journal of Cancer Treatment and Research 2014;2(5):45-7.

11. Mignogna MD, Fedele S, Lo Russo L, Lanza A, Marenzi G, Sammartino G. Gorham’s disease of the mandible mimicking periodontal disease on radiograph. J Clin Periodontol 2005;32(9):1022–6.