Document Type: Case Reports
Authors
1 Dept. of Pathology, JN Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India
2 Dept. of Surgery, JN Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India
3 Dept. of Orthopaedics, JN Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India
4 Department of Pathology, JN Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India.
Abstract
Chondromyxoid fibroma (CMF) is a rare benign cartilaginous tumor with a predilection for the bones of lower extremities and about one fourth of the tumors involve the foot.Radiologically, an eccentric lytic lesion with well defined margins is seen in the metaphysis of the bone. We hereby, report an 18 yr old young male who presented to Orthopedic Outpatient Department, JN Medical College, Aligarh Muslim University, India diagnosed with giant cell tumor of thethird metatarsal bone of right foot on radiography but on fine needle aspiration cytology (FNAC) the diagnosis of CMF was made. Preoperative diagnosis of this benign condition helped in doing minimum surgical intervention in the form of curettage along with bone grafting. Histopathology further confirmed the diagnosis of CMF. The case is being discussed to highlight the importance of FNAC to diagnose these uncommon benign bone lesions.
Keywords
- Handa U, Bal A, Mohan H, Bhardwaj S. Fine needle aspiration cytology in the diagnosis of bone lesions.Cytopathology 2005; 16:59–64.
- Walke VA, Nayak SP, Munshi MM, Bobhate SK. Cytodiagnosis of chondromyxoid fibroma. J Cytol 2010; 27:96-8.
- Layfield LJ, Ferreiro JA. Fine needle aspiration cytology of chondromyxoid fibroma: a case report. DiagnCytopathol 1988;4:148–51.
- Nielsen GP, Layfield LJ, Rosenberg AE. Neoplastic and tumor like lesion of bone. In: Silverberg SG, editor. Silverbergs principles and practice of surgical pathology and cytopathology. 4th ed. Philadelphia: Churchill Livingstone; 2006. pp. 701–83.
- Jaffe HL, Linchtenstein L. Chondromyxoid fibroma of bone; a distinctive benign tumor likely to be mistaken especially for chondrosarcoma. Arch Pathol (Chic) 1948;45:541–51.
- Daneshbod Y, Khademi B. Chondromyxoid fibroma of the mandible: A diagnostic pitfall on aspiration cytology of Parotid. ActaCytol 2008;52:636–8.
- Wolf DA, Chaljub G, Maggo WG, Gelman BB. Intracranial chondromyxoid fibroma. Report of a case and review of literature. Arch Pathol Lab Med1997;121:626–30.
- Dürr HR, Lienemann A, Nerlich A, Stumpenhausen B, Refior HJ. Chondromyxoid fibroma of bone. Arch Orthop Trauma Surg 2000; 120(1-2):42-7.
- Greenspan A (1989) Tumors of cartilage origin. OrthopClin North Am 1989; 20 :347–366.
- Feit EM, Dobbs BM. Chondromyxoid fibroma of the fourth metatarsal. J Am Podiatr Med Assoc 2000 Apr;90(4):211-6.
- Goldenhar AS, Neil J, Whittaker S. Chondromyxoid fibroma of a metatarsal and cuneiform.J Am Podiatr Med Assoc 1994; 84(8):413-5.
- Hazarika D, Kumar RV, Ramarao C, Mukherjee G, Pattabhirama V, ChadraShekhar M. Fine needle aspiration cytology of chondroblastoma and chondromyxoid fibroma: A report of 2 cases. Acta Cytol 1995;38:592–6.
- Gupta S, Dev G, Marya S. Chondromyxoid fibroma: A fine- needle aspiration diagnosis. DiagnCytopathol 1993;9:63–5.
- De Las Casas LE, Singh HK, Halliday BE, Xuf, Strausbauch PH, Silverman JF. Myxoid chondrosarcoma of sphenoid sinus and chondromyxoid fibroma of iliac bone: cytomorphologic findings of two distinct and uncommon myxoid lesion. Diagn Cytopathol 2000; 22:383–9.
- Bhamra JS, Al-Khateeb H, Dhinsa BS, Gikas PD, Tirabosco R, Pollock RC et al. Chondromyxoid fibroma management: a single institution experience of 22 cases. World J Surg Oncol 2014 Sep 12; 12:283.
