TY - JOUR ID - 43630 TI - A Rare Case of Metastasis of Renal Clear Cell Carcinoma to the Thyroid Gland, Presenting as a Goiter Nodule, Three Years After Nephrectomy JO - Iranian Journal of Pathology JA - IJP LA - en SN - 1735-5303 AU - Moradi Tabriz, Hedieh AU - Eftekhar-Javadi, Arezoo AU - Zandnejadi, Atiieh AD - Department of Anatomical and Surgical Pathology and Laboratory Medicine, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran Y1 - 2020 PY - 2020 VL - 15 IS - 4 SP - 342 EP - 345 KW - Renal cell carcinoma KW - Thyroid gland KW - Metastasis KW - Multinodular Goiter DO - 10.30699/ijp.2020.117839.2282 N2 - Thyroid gland metastatic tumors are rare in clinical practice. Clear cell RCC is one of common metastatic tumors to thyroid. We here reported a case of incidentally found clear cell renal carcinoma metastasis to the thyroid gland 3 years after nephrectomy, in the thyroidectomy procedure performed for the patient due to the thyroid enlargement caused by multinodular goiter. A 65-year-old Iranian man with a history of multinodular goiter referred to our surgery clinic for thyroidectomy because of compressive effects on the trachea. Patient had a history of nephrectomy due to clear cell RCC 3 years ago. After thyroidectomy, gross and histological examination of thyroid revealed clear cell renal carcinoma metastasis to the thyroid gland in the setting of a multinodular goiter. The diagnosis was confirmed by immunohistochemistry staining. Patients with multinodular goiter are more prone to present with metastasis to thyroid gland if they have a history of malignancy, especially renal cell carcinoma. UR - https://ijp.iranpath.org/article_43630.html L1 - https://ijp.iranpath.org/article_43630_77e389356c1c045a63b9002a4f28aa60.pdf ER -