TY - JOUR ID - 14584 TI - Clinico-Pathological Study of Cutaneous Granulomatous Lesions- a 5 yr Experience in a Tertiary Care Hospital in India JO - Iranian Journal of Pathology JA - IJP LA - en SN - 1735-5303 AU - Chakrabarti, Srabani AU - Pal, Subrata AU - Biswas, Biplab AU - Bose, Kingshuk AU - Pal, Saswati AU - Pathak, Swapan AD - Dept. of Pathology, College of Medicine and Sagore, Dutta Hospital.Kolkata, India. AD - Dept. of Pathology, Bankura Sammilani Medical College, Bankura, India. AD - Dept. of Pathology, NRS Medical College, Kolkata, India. AD - Dept. of Pathology, Calcutta National Medical College, Kolkata. India. Y1 - 2016 PY - 2016 VL - 11 IS - 1 SP - 54 EP - 60 KW - Granuloma KW - Histopathology KW - skin biopsy DO - N2 - Background: Granulomatous dermatoses are common skin pathology, often need histopathological confirmation for diagnosis. Histologically six sub-types of granulomas found in granulomatous skin diseases- tuberculoid, sarcoidal, necrobiotic, suppurative, foreign body & histoid type. The aims of the present study were clinico-pathological evaluation of granulomatous skin lesions and their etiological classification based on histopathological examination. Methods: It was a five years (Jan 2009- Dec 2013) retrospective study involving all the skin biopsies. Detailed clinical and histopathological features were analyzed and granulomatous skin lesions were categorized according to type of granuloma & etiology. Special stains were used in few cases for diagnostic purpose. Results: Among 1280 skin biopsies, 186 cases (14.53%) were granulomatous skin lesions with a ratio 1:24. In histopathological sub-typing, tuberculoid granuloma was most common type (126 cases, 67.74%). Most common etiology of granuloma in the study was leprosy (107 cases, 57.52%). Other etiologies were cutaneous tuberculosis, foreign body granulomas, fungal lesions, cutaneous leishmaniasis, sarcoidosis and granuloma annulare. Conclusion: Histopathology is established as gold standard investigation for diagnosis, categorization and clinico-pathological correlation of granulomatous skin lesions.  UR - https://ijp.iranpath.org/article_14584.html L1 - https://ijp.iranpath.org/article_14584_8dc0cb21d223da7159337f0076fd27e4.pdf ER -