Farname Inc in collaboration with Iranian Society of Pathology
Iranian Journal of Pathology
1735-5303
2345-3656
9
1
2014
01
01
Spectrum of Malignant Transformation in Marjolins Ulcer: Our Experience of This Rare Phenomenon
1
8
EN
Mitra
Mustaphi Ruplekha
Dept. of Pathology, ESI-PGIMSR, Joka, Kolkata, India
Gon
Sonia
Dept. of Pathology, ESI-PGIMSR, Joka, Kolkata, India
drmarur@yahoo.com
Bhattacharyya
Roop Narayan
Dept. of Plastic and Reconstructive Surgery, R.G.Kar Medical College, Kolkata, India
Background & Objective: Chronic non healing ulcers or scar undergoing malignant transformation is a rare phenomenon with an estimated incidence of 2%. Though, numerous predisposing factors have been identified, still it is rarely diagnosed and commonly mistaken for a benign condition. The objective of this study was to verify the efficacy of the Fine Needle Aspiration Cytology/ Scrape cytology of chronic non healing ulcers, and its use in the early detection of the malignant transformation, thereby facilitating early management. Methods: A total of 10 cases of chronic non healing ulcer with malignant transformation were included in the study where the initial diagnosis was made on Fine Needle Aspiration Cytology/Scrape cytology and later on confirmed on histopathology. Results: Squamous cell carcinoma (7 cases), acantholytic variant of Squamous Cell Carcinoma (1 case), malignant fibrous histiocytoma (1 case) and carcinosarcoma (1 case) was seen. A 100% concordance with histopathology was seen in Squamous cell carcinoma cases. Because of the rarity of the case and unusual transformation, high grade pleomorphic spindle cell carcinoma was the cytological diagnosis in case of Malignant Fibrous Histiocytoma. Conclusion: Marjolin ulcer arising out of chronic non healing ulcers can prove to be a precursor of any different kind of malignancies. Fine Needle Aspiration Cytology/scrape cytology can be used as a first line diagnostic modality for the early diagnosis as it is a fast and safe method with high rate of accuracy, sensitivity and specificity
Skin Ulcer,Cancer,Fine needle aspiration,Cytology
https://ijp.iranpath.org/article_7820.html
https://ijp.iranpath.org/article_7820_c07a42e052f824870fba03985a2ddc3c.pdf
Farname Inc in collaboration with Iranian Society of Pathology
Iranian Journal of Pathology
1735-5303
2345-3656
9
1
2014
01
01
Comparison of Placental Morphology and Histopathology of Intrauterine Growth Restriction and Normal Infants
9
16
EN
Nayereh
Ghomian
Dept. of Obstetrics and Gynecology, Faculty of Medicine, Ovulation Dysfunction Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
ghomiann@mums.ac.ir
Sakineh
Amouian
Dept. of Pathology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Fatemeh
Tavassoli
Dept. of Obstetrics and Gynecology, Faculty of Medicine, Ovulation Dysfunction Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
Taraneh
Arbabzadeh
Dept. of Obstetrics and Gynecology, Faculty of Medicine, Ovulation Dysfunction Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
Background & Objective: Chronic non healing ulcers or scar undergoing malignant transformation is a rare phenomenon with an estimated incidence of 2%. Though, numerous predisposing factors have been identified, still it is rarely diagnosed and commonly mistaken for a benign condition. The objective of this study was to verify the efficacy of the Fine Needle Aspiration Cytology/ Scrape cytology of chronic non healing ulcers, and its use in the early detection of the malignant transformation, thereby facilitating early management. Methods: A total of 10 cases of chronic non healing ulcer with malignant transformation were included in the study where the initial diagnosis was made on Fine Needle Aspiration Cytology/Scrape cytology and later on confirmed on histopathology. Results: Squamous cell carcinoma (7 cases), acantholytic variant of Squamous Cell Carcinoma (1 case), malignant fibrous histiocytoma (1 case) and carcinosarcoma (1 case) was seen. A 100% concordance with histopathology was seen in Squamous cell carcinoma cases. Because of the rarity of the case and unusual transformation, high grade pleomorphic spindle cell carcinoma was the cytological diagnosis in case of Malignant Fibrous Histiocytoma. Conclusion: Marjolin ulcer arising out of chronic non healing ulcers can prove to be a precursor of any different kind of malignancies. Fine Needle Aspiration Cytology/scrape cytology can be used as a first line diagnostic modality for the early diagnosis as it is a fast and safe method with high rate of accuracy, sensitivity and specificity.
Skin Ulcer,Cancer,Fine needle aspiration,Cytology
https://ijp.iranpath.org/article_7821.html
https://ijp.iranpath.org/article_7821_11ac08a426937424341fec37bff59635.pdf
Farname Inc in collaboration with Iranian Society of Pathology
Iranian Journal of Pathology
1735-5303
2345-3656
9
1
2014
01
01
Quality Control Planning of a Hepatitis B Viral Load Laboratory-Developed Assay
17
22
EN
Fatemeh
Nili
Dept. of Pathology, Tehran University of Medical Sciences, Tehran, Iran
Reza
Shahsiah
Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran
shahsiah@yahoo.com
Farid
Azmoudeh Ardalan
Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran
Mohsen
Nassiri Toosi
Dept. of Gastroenterology and Hepatology, Tehran University of Medical Sciences, Tehran, Iran
Alireza
Abdollahi
0000-0002-5714-967X
Dept. of Gastroenterology and Hepatology, Tehran University of Medical Sciences, Tehran, Iran
dr_p_abdollahi@yahoo.com
Background and Objectives: HBV DNA monitoring is important in management of chronic viral hepatitis B infection. HBV DNA measurements are carried out over period of months to years. So the analytical system must be stable and reproducible. The aim of this study was to determine the performance characteristics and to plan a statistical quality control system of a laboratory-developed real-time quantitative PCR assay for HBV DNA quantification. Methods: Values of systematic and random error at two clinical decision points;4.2 Log IU/mL (20000 IU/mL) and 3.2 Log IU/mL (2000 IU/mL) were determined. Candidate quality control procedures were selected and performance of the method by application of normalized operational process specification (OPSpecs) charts was determined. Results: The performance of the assay at level of 4.2 Log IU/mL and 3.2 Log IU/mL were excellent and good respectively. Moreover, a13.5S rule with two measurements offered 90% probability of error detection at level of 4.2 Log IU/mL, while no rule offered 90% probability of error detection at level of 3.2 Log IU/mL. Conclusion: Minimizing the formation of primer-dimer and nonspecific products and concentrating the target DNA during the purification process are proposed for accurate quantitative PCR particularly when CT values are high.
Hepatitis B,quality control,Real-Time Polymerase Chain Reaction,Virus Load
https://ijp.iranpath.org/article_8233.html
https://ijp.iranpath.org/article_8233_656b9257fba01b8432d893299596c9ca.pdf
Farname Inc in collaboration with Iranian Society of Pathology
Iranian Journal of Pathology
1735-5303
2345-3656
9
1
2014
01
01
First Seroprevalence Survey of Children with Tularemia Infection in Chaharmahal va Bakhtiari Province, Iran
23
27
EN
Abolfazl
Khoshdel
Dept. Of Pediatric Infectious, Shahrekord University Of Medical Sciences, Shahrekord, Iran
Ebrahim
Saedi Dezaki
Dept. Of Medical Parasitology, Kerman University Of Medical Science, Kerman, Iran
saedi_e@yahoo.com
Froozan
Ganji
Dept. Of Social Medicine, Shahrekord University Of Medical Sciences, Shahrekord, Iran
Roya
Habibian
Dept. Of Infectious Disease, Shahrekord University Of Medical Sciences, Shahrekord, Iran
Reza
Imani
Dept. Of Infectious Disease, Shahrekord University Of Medical Sciences, Shahrekord, Iran
Elham
Taheri
Dept. Of Pathology, Kerman University Of Medical Science, Kerman, Iran
Azar
Nikkhah
General Physician, Shahrekord University Of Medical Sciences, Shahrekord, Iran
Background and Objectives: An increasing number of tularemia was reported in all over the world. This infection is characterized by different clinical syndromes that can be considered in differential diagnosis of infectious disease. Despite effective antibiotics against Francisella tularensis, this infection is still as one of the agent of mortality and disability among infectious disease.The aim of this study was investigation of seroepidemiological of F. tuleransis among children between 2-18 years old in a risky zone in Iran.
Methods: This cross-sectional, laboratory-based study in two distinct villages Saragha seyed and Khoye in Chaharmahal va bakhtiari Province involved 183 children, adolescents who had no sign and symptom of disease and were screened for tularemia immunoglobulins G (IgG), using the ELISA-based quantitative assay.
Results: In general, from 183 children 11 persons (6%) were seropositive, compared with 172 persons (94%) were seronegative.
Conclusion: According to the high prevalence of antibodies against F. tularensis in this study, this infection must be considered as differential diagnosis of infectious disease in suspect patients.
Tularemia,Seroprevalence,Children,Iran
https://ijp.iranpath.org/article_8234.html
https://ijp.iranpath.org/article_8234_0a7ad21b66784caa794012bc26f9d174.pdf
Farname Inc in collaboration with Iranian Society of Pathology
Iranian Journal of Pathology
1735-5303
2345-3656
9
1
2014
01
01
Tongue Squamous Cell Carcinoma: A Clinical Study
28
32
EN
Hamidreza
Azimi
Dental Research Center, Faculty of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran
Saeedeh
Khajehahmadi
Dental Research Center, Faculty of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran
Amin
Rahpeyma
Oral and Maxillofacial Diseases Research Center, Faculty of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran
rahpeymaa@mums.ac.ir
Background and Objectives: Squamous cell carcinoma of the tongue (SCCOT) is the most common malignant neoplasm in oral cavity. At the time of the diagnosis of SCCOT regional metastases with a high mortality rate are common, which is due to the extensive lymphatic system drainage of the tongue. Although the level of healthcare has significantly improved, the survival rate is still low with an unsatisfactory cure rate. The present study was designed to establish a clinical review on adults with SCCOT and to determine whether the rate of SCCOT has been changed over the 20-year.
Methods: A cohort of 102 patients was recruited for this retrospective study. The study was carried out by reviewing the medical reports and case notes of patients with histologically confirmed SCCOT.
Results: The peak incidence was observed between 60 and 70 years. Stage I disease was found in 24, stage II in 64, stage III in 10 and stage IV in four patients. Seventy-three patients were treated with combined therapy; surgery and radiation, whereas, 29 patients received only surgery. The overall 5-year survival was 60%. Thirty patients developed tumor recurrence including 12 local, 12 nodal, four locoregional, and two distant. Thirty-four patients died during the follow-up period, six with persistent disease, and 62 remained cancer free, giving a mortality and morbidity rate of 39%.
Conclusion: This study recommends aggressive early treatment of patients with SCCOT including resection of the primary tumor with a safe margin (1.5cm) in addition to an appropriate neck dissection.
Tongue,Squamous cell carcinoma,Iran
https://ijp.iranpath.org/article_8235.html
https://ijp.iranpath.org/article_8235_e88768d2acba9c37ce1b74e3534493ed.pdf
Farname Inc in collaboration with Iranian Society of Pathology
Iranian Journal of Pathology
1735-5303
2345-3656
9
1
2014
01
01
Diabetes Mellitus Type1 and Neuronal Degeneration in Ventral and Dorsal Hippocampus
33
37
EN
Khadijeh
Foghi
Dept. of Anatomical Scienesc, North Khorasan University of Medical Sciences, Bojnurd, Iran
Shahriar
Ahmadpour
0000-0002-7744-3358
Dept. of Anatomical Scienesc, North Khorasan University of Medical Sciences, Bojnurd, Iran
sh.ahmadpour@nkums.ac.ir
Background and Objectives: Studies have documented the morhplogical, neurochemical and functional difference between the dorsal and ventral zones of hippocampus. The aim of this study was to assess the effects of chronic diabetes mellitus type1 on ventral and dorsal zones of hippocampus.
Methods: Experimental diabetes was induced by stereptozotocin at a dose of 60 mg/kg. At the end of 8 weeks the brains were removed and stained by cresyl violet. The number of dark neurons in CA1 and CA3 regions of dorsal and ventral zones of hippocampus was counted by modified stereological method.
Results: The number of dead neurons in CA3 ventral showed significant level of difference (P<0.05) in comparison to CA3 dorsal. The number of dead neurons in CA1 ventral and CA1 dorsal showed also significant difference (P<0.05)
Conclusion: The results of our study indicative of more vulnerability of ventral zones the dorsal zone of hippocampus to diabetes mellitus type 1.
Type 1 diabetes mellitus,Hippocampus,Neuron Degeneration,Rat
https://ijp.iranpath.org/article_8236.html
https://ijp.iranpath.org/article_8236_09b0fc9f537145178977dec99c95cb37.pdf
Farname Inc in collaboration with Iranian Society of Pathology
Iranian Journal of Pathology
1735-5303
2345-3656
9
1
2014
01
01
Microbial and Antibiotic Susceptibility Profiles among Pleural Effusion Exudative Samples
38
44
EN
Alireza
Abdollahi
0000-0002-5714-967X
Dept. of Pathology, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
dr_p_abdollahi@yahoo.com
Saeed
Shoar
evelopment Association for Clinical Study (DACS), Student Scientific Research Center (SSCR), Tehran University of Medical Sciences, Tehran, Iran
Hiva
Saffar
Dept. of Pathology, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
Hana
saffar
Dept. of Pathology, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
Azita
Yazdi
Dept. of Pathology, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
Background and Objectives:Infection of pleural fluid is a common disease and because of antibiotic administration, the microbiology of this fluid has changed. The aim of this study was to determine the common bacteria and suitable antibiotics for treatment in pleural effusion (PE).
Materials and Methods: In this cross sectional study, 1210 samples with exudative features were cultured for possible growth of microbial pathogens and then examined for antibiotics sensitivity. Samples’ characteristics were then analyzed according to the age and sex difference.
Results: Among 1210 exudative pleural effusions, 38.2% were obtained from females and 61.8% from males. Of 142 pleural fluid samples, 11.7% had a positive culture. Aerobic gram negative organism was the most common type among the other samples with a prevalence of 52% followed by aerobic gram positive (25.3%), non- aerobic gram negative (15.7%), non- aerobic gram positive (6.2%) and fungi (0.8%). E. coli, Staphylococcus Aureus and Acinetobacter baumannii were the most common types of organism among adult population.
Conclusion:Aerobic gram positive bacteria had the highest prevalence among the pathogens, and cephalosporins, aminopenicillins and β-lactams were the most effective antibiotics for their treatment.
Pleural effusion,Bacterial infection,Bacterial Sensitivity Test
https://ijp.iranpath.org/article_8237.html
https://ijp.iranpath.org/article_8237_fd5d16f367351cd448d419306409b886.pdf
Farname Inc in collaboration with Iranian Society of Pathology
Iranian Journal of Pathology
1735-5303
2345-3656
9
1
2014
01
01
Frequency of Errors in Clinical Laboratory Practice
45
49
EN
Fauzia
Sadiq
Dept. of Pathology, Shalamar Medical & Dental College Lahore, Pakistan
Farzana
Yasmeen
Dept. of Pathology, Shalamar Medical & Dental College Lahore, Pakistan
Asim
Mumtaz
Dept. of Pathology, Shalamar Medical & Dental College Lahore, Pakistan
Warda
Hussain
Dept. of Pathology, Shalamar Medical & Dental College Lahore, Pakistan
Tauqeer Ali
Butt
Dept. of Pathology, Shalamar Medical & Dental College Lahore, Pakistan
Sajid
Azeem Qureshi
Dept. of Pathology, Shalamar Medical & Dental College Lahore, Pakistan
Muhammad
Ibrahim
Dept. of Pathology, Shalamar Medical & Dental College Lahore, Pakistan
ibrahim_ap98@yahoo.com
Background and Objective: Laboratory errors are one of the major factors that affect the diagnosis, prognosis, treatment and monitoring in patients.The objective of study is to evaluate the frequency and type of errors in different phases of testing at the Pathology Department of the Shalamar Hospital, Lahore and to evaluate the causes of errors.
Methods: This observational study was carried out in Shalamar Hospital Laboratories Lahore from 1<sup>st</sup> July 2011 to 31<sup>st</sup> December 2011. Errors detected and documented on daily basis.
Results: A total of 127,500 samples were received and processed during the six months period. Out of the total samples, 1530 (1.2) errors were detected. Among all errors pre-analytical errors were most common, with a frequency of 70.4%, post-analytical 17.5% and analytical 12.1%.
Conclusions: Our study demonstrates the types and frequencies of errors. It is very important to monitor the all phases so to reduce the frequency of error for better reporting of lab results, ultimately which ensures the patient well-being.
Clinical Laboratory,Errors,Pakistan
https://ijp.iranpath.org/article_8238.html
https://ijp.iranpath.org/article_8238_09ecd4a7082c97f36f6d2ba3001c2ebe.pdf
Farname Inc in collaboration with Iranian Society of Pathology
Iranian Journal of Pathology
1735-5303
2345-3656
9
1
2014
01
01
Hematological Reference Values for Healthy Males in the Central Part of Iran
50
55
EN
Amitis
Ramezani
Dept. of Clinical Research, Pasteur Institute of Iran, Tehran, Iran
Mandana
Shams
TPIRC (Tuberculosis and Pediatric Infectious Research Center), Arak University of Medical Sciences, Arak, Iran
Nader
Zarinfar
TPIRC (Tuberculosis and Pediatric Infectious Research Center), Arak University of Medical Sciences, Arak, Iran
Mohammad
Banifazl
Iranian Society for Support of Patients with Infectious Disease, Tehran, Iran
Arezoo
Aghakhani
Dept. of Clinical Research, Pasteur Institute of Iran, Tehran, Iran
araghakhani@hotmail.com
Ali
Eslamifar
Dept. of Clinical Research, Pasteur Institute of Iran, Tehran, Iran
Fatemeh- Alsadat
Mahdaviani
Blood Transfusion Organization Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran
Ghorban
Deiri
Blood Transfusion Organization Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran
Masoomeh
Sofian
TPIRC (Tuberculosis and Pediatric Infectious Research Center), Arak University of Medical Sciences, Arak, Iran
dr.sofian@arakmu.ac.ir
Background and Objectives: Laboratory reference values are an important tool for clinical management of patients. Reference values being used in most laboratories in Iran have been provided from the established reference values from developed countries. However, several variables can affect on these laboratory parameters. Therefore, this study was carried out to establish the reference values of hematological parameters in the blood donors of central province of Iran as a general population.
Methods: Blood samples of 1100 male blood donors were collected consecutively from Blood Transfusion Organization. Complete blood cell (CBC) count in 2012 and differential was performed using an automated hematology analyzer.
Results: The median and 95% reference values (2.5<sup>th</sup>-97.5<sup>th</sup>) for Hb and platelet counts were 15.5 g/dl (14.1-17.7) and 209 ×10<sup>9 </sup>cells/L (151-322) respectively. The median for total WBC count, neutrophil, lymphocyte, monocyte and eosinophil were 6.7 ×10<sup>9 </sup>cells/L (4.3-11.2), %58 (%50-%70), 40% (30-49%), 0% (0-2) and %1 (0-3%), respectively.
Conclusion: The hematological profile of the population in central province of Iran was different from the reports of other countries and also the standards reference ranges described in textbook. So, further nationwide study should be carried out to establish the hematological reference values of the Iranian population as a whole.
Hematology,Reference Value,Male,Iran
https://ijp.iranpath.org/article_8239.html
https://ijp.iranpath.org/article_8239_edbd8dc53403803e9122d5acd1f05591.pdf
Farname Inc in collaboration with Iranian Society of Pathology
Iranian Journal of Pathology
1735-5303
2345-3656
9
1
2014
01
01
Chordoma of the Lower Back in an Adolescent: A Rare Cytologic Presentation
56
59
EN
Kafil
Akhtar
Dept. Of Pathology, Aligarh Muslim University, Aligarh, India
drkafilakhtar@gmail.com
Shamshad
Ahmad
Dept. Of Pathology, Aligarh Muslim University, Aligarh, India
Rana
Sherwani
Dept. Of Pathology, Aligarh Muslim University, Aligarh, India
Chordomas are low-grade malignant tumors of bone that occur almost exclusively in the axial skeleton. Chordomas are rare in children and adolescents and comprise <5% of all cases and the site of development is at the skull base. These tumors are believed to behave more aggressively than chordomas in adults and may have unusual morphology. We herein present a rare case of chordoma in a 20-year-old male with low back mass, diagnosed on fine needle aspiration cytology.
https://ijp.iranpath.org/article_8240.html
https://ijp.iranpath.org/article_8240_d2bff6c8c0b9a6b28ad5b2aa497cdc0a.pdf
Farname Inc in collaboration with Iranian Society of Pathology
Iranian Journal of Pathology
1735-5303
2345-3656
9
1
2014
01
01
Myeloid Sarcoma Presenting with Lateral Cervical Mass and Eosinophilia; a Diagnostic and Therapeutic Dilemma: Case Report
60
65
EN
Moeinadin
Safavi
Dept. of Pathology, School of Medicine, Kerman University Of Medical Sciences, Kerman, Iran
Vahid
Moazed
Dept. of Oncology, School of Medicine, Kerman University Of Medical Sciences, Kerman, Iran
Hamid
Tabrizchi
Dept. of Pathology, School of Medicine, Kerman University Of Medical Sciences, Kerman, Iran
Maryam
Mohit
Dept. of Pathology, School of Medicine, Kerman University Of Medical Sciences, Kerman, Iran
Jahanbanoo
Shahryari
Dept. of Oncology, School of Medicine, Kerman University Of Medical Sciences, Kerman, Iran
shahriari_j@sums.ac.ir
Myeloid sarcoma is a rare extramedullary tumor of immature myeloid cells. It has been very rarely reported as lateral cervical mass in English literature. Myeloid sarcoma has also been reported with marked eosinophilia. Here we present a 17 year old boy with lateral cervical mass and persistent eosinophilia. The mass was isointense in MRI and homogenously enhanced after contrast injection which were not specific. Then, microscopic findings revealed blastoid cells with positive reaction for CD68 and CD117 which were highly in favor of myeloid sarcoma rather than its great mimicker, high grade lymphoma.
https://ijp.iranpath.org/article_8241.html
https://ijp.iranpath.org/article_8241_7ea791eabe552f69e7320ca210275e15.pdf
Farname Inc in collaboration with Iranian Society of Pathology
Iranian Journal of Pathology
1735-5303
2345-3656
9
1
2014
01
01
A Case of Epithelial Myoepithelial Carcinoma – Correlation of IHC & Histopathological Findings
66
70
EN
Atul
Shrivastav
Dept. of Pathology, C. U. Shah Medical College, Surendranagar, India
atulshri@ymail.com
Umang
V. Patel
Dept. of Pathology, C. U. Shah Medical College, Surendranagar, India
Sanjay
Gandhi
Green Cross Pathology and Molecular Laboratory, Ahmedabad, India
Harsh
A. Shah
Dept. of pathology, Shri M.P. Shah Medical college, Jamnagar, India
Epithelial myoepithelial carcinoma is a rare biphasic low grade neoplasm of salivary glands; it most commonly occurs in the parotid gland but can also arise in minor salivary glands. Here a case of 58-year-old female presented with left cheek swelling of one-year duration. CT scan revealed a localized submandibular salivary gland tumor mass not involving surrounding tissues. Histological examination showed a mixture of ductal elements; cuboidal cells bordering small lumina surrounded by polygonal clear cells of myoepithelial component without any evidence of nuclear atypia or mitotic figures. Final diagnosis of epithelial myoepithelial carcinoma was made on the basis of characteristic morphological and immunohistochemical features.
Epithelial- myoepithelial Carcinoma,Salivary Gland,Case Report
https://ijp.iranpath.org/article_8242.html
https://ijp.iranpath.org/article_8242_10a50883779f842648772b104fac098d.pdf
Farname Inc in collaboration with Iranian Society of Pathology
Iranian Journal of Pathology
1735-5303
2345-3656
9
1
2014
01
01
Florid Adnexal Polypoid Endometriosis Associated with Very High Serum Ca - 125 Levels Mimicking Ovarian Malignancy
71
76
EN
Srinivas
Ghante Nagaraj
Dept. Of Pathology, SBL Diagnostics, Mysore, India
Anitha
Chalageri
Dept. Of Pathology, SBL Diagnostics, Mysore, India
anitha.chalageri@gmail.com
Anjana
Gupta
Dept. Of Pathology, SBL Diagnostics, Mysore, India
Manjula
Vijayanand
Dept. Of Pathology, SBL Diagnostics, Mysore, India
We report a case of florid polypoid endometriosis presenting with advanced bulky disease in pelvis with serum CA – 125 levels of 7844U/ml. The extent of tumor, CT scan findings, elevated serum CA – 125 levels were suggestive of ovarian malignancy. Histopathology demonstrated endometrial glands and stroma. Glands were neither crowded nor complex and were separated by a fibromatous stroma that contained endometrial stromal cells. These features were consistent with diagnosis of polypoid endometriosis, a recently described entity with a clinical presentation completely different from conventional endometriosis. Our case emphasizes the association of high levels of CA – 125 with benign gynaecologic conditions.
Endometriosis,Pelvis,Tumor,CA 125 Antigen
https://ijp.iranpath.org/article_8243.html
https://ijp.iranpath.org/article_8243_e030282b967780aebaa7b5884b22ed5c.pdf
Farname Inc in collaboration with Iranian Society of Pathology
Iranian Journal of Pathology
1735-5303
2345-3656
9
1
2014
01
01
Extrapulmonary Tuberculosis Masquerading Neoplasm: A Series of Seven Cases Diagnosed by FNAC
77
78
EN
Sulekha
Ghosh
Dept. of Pathology, Malda Medical College, Malda, West Bengal, India
ghosh.drtapan@gmail.com
Arindam
Karmakar
Dept. of Pathology, Burdwan Medical College, West Bengal, India
Nikhilesh
Dewasi
Dept. of Pathology, Burdwan Medical College, West Bengal, India
Krishnendu
Das
Dept. of Pathology, Malda Medical College, Malda, West Bengal, India
Debanjan
Bhattacharjee
Dept. of Pathology, Burdwan Medical College, West Bengal, India
Tapan Kumar
Ghosh
Dept of Pathology, Calcutta National Medical College, Kolkata, India
https://ijp.iranpath.org/article_8244.html
https://ijp.iranpath.org/article_8244_81e5c6369a77a72646a29e399e95731f.pdf
Farname Inc in collaboration with Iranian Society of Pathology
Iranian Journal of Pathology
1735-5303
2345-3656
9
1
2014
01
01
Osteoblastoma of Mandible:A Rare Clinical Presentation
79
80
EN
Vijaylaxmi
Madalli
Dept. of Oral Medicine and Radiology, SDM College of Dental Sciences, Sattur, Dharwad, India
drvijaylaxmi@yahoo.co.in
Shrinivas
M. Basavaraddi
Dept. of Orthodontics, SDM College of Dental Sciences, Sattur, Dharwad, India
Venkatesh
Naikmasur
Dept. of Oral Medicine and Radiology, SDM College of Dental Sciences, Sattur, Dharwad, India
Krishna
Burde
Dept. of Oral Medicine and Radiology, SDM College of Dental Sciences, Sattur, Dharwad, India
Priya
Horatti
Dept. of General Dentistry, SDM College of Dental Sciences, Sattur, Dharwad, India
https://ijp.iranpath.org/article_8245.html
https://ijp.iranpath.org/article_8245_b6abcfd8117fcd232122fa340a0fb8f2.pdf