Volume 15 (2020)
Volume 14 (2019)
Volume 13 (2018)
Volume 12 (2017)
Volume 11 (2016)
Volume 10 (2015)
Volume 9 (2014)
Volume 8 (2013)
Volume 7 (2012)
Volume 6 (2011)
Volume 5 (2010)
Volume 4 (2009)
Volume 3 (2008)
Volume 2 (2007)
Volume 1 (2006)
Hematopathology
1. Cytogenetics and Revised International Staging System (R-ISS): Risk Stratification in Multiple myeloma - A Retrospective Study in Indian Population

Chethana Babu Udupa; KARTHIK UDUPA; Ananth Pai; Prathika Sherigar

Articles in Press, Accepted Manuscript, Available Online from 24 May 2020

http://dx.doi.org/10.30699/ijp.2020.105128.2078

Abstract
  Background & Objective: Cytogenetic abnormalities in Multiple myeloma (MM) has emerged as the most important factor that determine the prognosis and survival. Fluorescence in situ hybridization (FISH) can detect a greater number of cytogenetic abnormalities as compared to conventional karyotyping ...  Read More

Hematopathology
2. The Survival of Patients with t(15;17)(q22;q12) Positive Acute Promyelocytic Leukemia: A Study in North-East of Iran

Hossein Ayatollahi; Ali Bazi; Mohammad Hadi Sadeghian; Ali Fani; Payam Siyadat; Maryam Sheikhi; Omolbanin Sargazi-aval

Articles in Press, Accepted Manuscript, Available Online from 23 May 2020

http://dx.doi.org/10.30699/ijp.2020.101417.2007

Abstract
  Background & Objective: Acute promyelocytic leukemia (APL) with t(15;17)(q22;q12) is a relatively common subtype of acute myeloid leukemia (AML).  Here, our objective was to ascertain the survival of patients with this leukemia in north-east of Iran. Methods: Survival rates of 42 APL patients ...  Read More

Hematopathology
3. Characterization of Immunophenotypic Aberrancies in Adult and Childhood Acute Lymphoblastic Leukemia: Lessons from Regional Variation

Mitra Rezaei; Sandra Refoua; Najme Esfandiari; Masoud Shamaei

Volume 15, Issue 1 , Winter 2020, , Pages 1-7

http://dx.doi.org/10.30699/ijp.2019.93974.1926

Abstract
  Background & Objective:Although the antigen expression patterns of acute lymphoblastic leukemia (ALL) are well known, this study attempted to evaluate commonly used immune markers for immunophenotyping of acute leukemia to set the minimum of necessary diagnostic panels by flow cytometry.Methods:This ...  Read More

Hematopathology
4. Mast Cell Leukemia with Ascites and Multiple Organs Damage

Elham Jafari; Ali Hadipour; Behjat Kalantari Khandani; Firoozeh Abolhasani

Volume 14, Issue 3 , Summer 2019, , Pages 265-269

http://dx.doi.org/10.30699/ijp.2019.96187.1948

Abstract
  Mast Cell Leukemia (MCL), a rare subtype of systemic mastocytosis is defined by bone marrow involvement as atypical and aleukemic mast cells, if more than 20% and less than 10% of peripheral WBCs are mast cells, respectively. We met a case of aleukemic MCL presenting with anemia and ascites for 2 years, ...  Read More

Hematopathology
5. Dengue with Normal Platelet Count and no Hemoconcentration: Automated Hematogram in Cases with Underlying Thalassemia

Beuy Joob; Viroj Wiwanitkit

Volume 14, Issue 2 , Spring 2019, , Pages 186-187

http://dx.doi.org/10.30699/ijp.14.2.186

Abstract
  Dear Editor, Dengue is an important arbovirus infection. This infection can result in an acute febrile illness. The important hematological abnormalities included hemoconcentration and thrombocytopenia (1). Due to the decreased platelet count, the patient might develop petechiae and hemorrhagic complication. ...  Read More

Hematopathology
6. Prevalence of MPL (W515K/L) Mutations in Patients with Negative-JAK2 (V617F) Myeloproliferative Neoplasm in North-East of Iran

Seyyede Fatemeh Shams; Hossein Ayatollahi; Mohammad hadi Sadeghian; Monavar Afzal Aghaee; Sepideh Shakeri; Ehsan Yazdandoust; Maryam Sheikhi; Nafiseh Amini; Samane Bakhshi; Afsane Bahrami

Volume 13, Issue 4 , Autumn 2018, , Pages 397-402

Abstract
  Background and Objective: Janus kinase 2 (JAK2) and Myeloproliferative Leukemia (MPL) mutations are confirmatory indicators for Myeloproliferative Neoplasm (MPN). The current study was performed to determine the frequency of MPL mutation in MPN patients without JAK2 mutation, in order to assign MPL mutation ...  Read More

Hematopathology
7. Peripheral Blood-Derived Mesenchymal Stem Cells: Growth Factor-Free Isolation, Molecular Characterization and Differentiation

Noushin Pouryazdanpanah; Shahriar Dabiri; Ali Derakhshani; Reza Vahidi; Alireza Farsinejad

Volume 13, Issue 4 , Autumn 2018, , Pages 461-466

Abstract
  Background and Objectives: The mesenchymal stem cells derived from peripheral blood (PB) have been recognized as a promising source for allogeneic cell therapy. The aim of this study was to investigate the isolation, growth and differentiation ability of peripheral blood-isolated mesenchymal stem cells. ...  Read More

Hematopathology
8. Prognostic Value of EVI1 Expression in Pediatric Acute Myeloid Leukemia: A Systematic Review

Mohammad Hadi Sadeghian; Zahra Rezaei dezaki

Volume 13, Issue 3 , Summer 2018, , Pages 294-300

Abstract
  Acute myeloid leukemia (AML) as a distortion of blood cells involves the differentiation of hematopoietic stem cells. Several studies established the irregular overexpression of specific genes is a common finding in patients with AML. The ectopic viral integration site-1 (EVI1) gene is a proto-oncogene ...  Read More

Hematopathology
9. Non Secretory Multiple Myeloma With HCV Infection: A Rare Case Entity

Arun Puri; Heena Wadhwa; Navtej Singh

Volume 13, Issue 2 , Spring 2018, , Pages 281-284

http://dx.doi.org/10.30699/ijp.13.2.281

Abstract
  Multiple Myeloma is a neoplasm of B cell lineage characterized by excessive proliferation of abnormal plasma cells. It is characterized by a clinical  pentad of 1) anemia, 2) a monoclonal protein in the serum or the urine or both, 3) bone leisons and or bone pain, 4) hypercalcemia >11.5g/dl and ...  Read More

Hematopathology
10. Cutaneous Verrucous Carcinoma Superimposed on Chronically Inflamed Ileostomy Site Skin: A Case Report

Ali Yaghobi; Payam Azadeh; Behzad Nemati Honar

Volume 13, Issue 2 , Spring 2018, , Pages 285-288

http://dx.doi.org/10.30699/ijp.13.2.285

Abstract
  Verrucous carcinoma (VC) is a rare variant of well differentiated squamous cell carcinoma (SCC) which is usually found in oral cavity mucosa. Cutaneous verrucous carcinoma is a rare entity and in this paper we report a 43 years old man with VC superimposed on chronically inflamed skin of ileostomy site. ...  Read More

Hematopathology
11. Prognostic Significance of Reduction in Ki67 Index After Neoadjuvant Chemotherapy in Patients With Breast Cancer in Kerman Between 2009 And 2014

Vahid Moazed; Elham Jafari; Behjat Kalantari khandani; Ali Nemati; seyedamir benrazavi

Volume 13, Issue 1 , Winter 2018, , Pages 71-77

http://dx.doi.org/10.30699/ijp.13.1.71

Abstract
  Background and objective:Breast cancer is the most common malignancy among women. The Neoadjuvant chemotherapy is the treatment of choice for non-operable tumors. The Ki67 is a proliferation marker that can be used to predict the therapeutic response to chemotherapy and the patients' prognosis. Methods: ...  Read More

Hematopathology
12. Beware of Bone Marrow: Incidental Detection and Primary Diagnosis of Solid Tumours in Bone Marrow Aspiration and Biopsies; A Study of 22 Cases

Ruchita Tyagi; Aminder Singh; Bhavna Garg; Neena Sood

Volume 13, Issue 1 , Winter 2018, , Pages 78-84

http://dx.doi.org/10.30699/ijp.13.1.78

Abstract
  Background & objective: Introduction: First detection of any solid tumour as metastatic deposits in bone marrow directs clinicians to start searching for the primary tumour. Detection of bone marrow metastasis determines the stage of the malignancy, prognosis, mode of treatment, chemotherapeutic ...  Read More

Hematopathology
13. Herpes Simplex Virus and Langerhans Cell Histiocytosis

Maliheh Khoddami; Seyed Alireza Nadji; Paria Dehghanian

Volume 12, Issue 4 , Autumn 2017, , Pages 323-328

Abstract
  Background and objective: Langerhans cell histiocytosis (LCH) is a rare histiocytic proliferative disorder of unknown etiology and mainly affects young children. The histological feature is granuloma-like proliferation of langerhans-type dendritic cells. Although the possible role of viruses such ...  Read More

Hematopathology
14. Acute Myeloid Leukemia as the Main Cause of Pancytopenia in Iranian Population

Hasan Jalaeikhoo; Seyed Mohammad Hossein Kashfi; Pedram Azimzadeh; Ahmad Narimani; Katayon Gouhari Moghadam; Mohsen Rajaeinejad; Mehdi Ariana; Manouchehr Keyhani

Volume 12, Issue 3 , Summer 2017, , Pages 265-271

Abstract
  Background & objective: Pancytopenia is the reduction in the number of all 3 major cellular elements of blood and leads to anemia, leukopenia, and thrombocytopenia. A wide variety of etiologies result in pancytopenia including leukemia, aplastic anemia, and megaloblastic anemia. The current study ...  Read More

Hematopathology
15. Chromogenic in situ Hybridization Compared with Real Time Quantitative Polymerase Chain Reaction to Evaluate HER2/neu Status in Breast Cancer

Hossein Ayatollahi; Azar Fani; Ehsan Ghayoor Karimiani; Fateme Homaee; Arezoo Shajiei; Maryam Sheikh; Sepideh Shakeri; Seyyede Fatemeh Shams

Volume 12, Issue 2 , Spring 2017, , Pages 128-134

Abstract
  Background and objective: The assessment of human epidermal growth factor receptor 2 (HER2) status has become of great importance in the diagnosis of breast cancer. The aim of this study was to investigate the diagnostic value of quantitative Polymerase Chain Reaction (qPCR) and Chromogenic In Situ Hybridization ...  Read More

Hematopathology
16. Aggressive Fibromatosis, Clinicopathologic Findings of 25 Cases; A Single-Center Experience and Review of the Literature

Bita Geramizadeh; Fatemeh Jalali

Volume 12, Issue 1 , Winter 2017, , Pages 20-24

Abstract
  Background: Aggressive fibromatosis is a rare benign tumor with no potential for metastasis; however, its aggressive nature causes treatment failure and episodes of recurrence. There is no report from Iran about the treatment of this tumor, and all published articles are single-case reports, therefore ...  Read More

Hematopathology
17. Fluorescent in Situ Hybridization and Real-Time Quantitative Polymerase Chain Reaction to Evaluate HER-2/neu Status in Breast Cancer

Fatemeh Homaei Shandiz; Azar Fani; Sepideh Shakeri; Maryam Sheikhi; Abouzar Ramezani Farkhani; Arezoo Shajiei; Hossein Ayatollahi

Volume 12, Issue 1 , Winter 2017, , Pages 67-73

Abstract
  Background:Breast cancer remains the most common and second lethal cancer in females. HER-2/neu is one of the most important amplified oncogene in breast cancer. The amplification of HER-2 is correlated with decreased survival, metastasis, and early recurrence.  The amplification of HER-2/neu gene ...  Read More

Hematopathology
18. Jaw Pain as a First Presentation in the Diagnosis of Breast Cancer

Payam Azadeh; Nasser Rakhashni; Ali Yaghobi Joybari; Pegah Gorji Bayani; Samaneh Sarbaz; Maryam Farasatinasab

Volume 11, Issue 5 , Autumn 2016, , Pages 439-442

Abstract
  The oral cavity is uncommon site for metastatic disease usually discovered secondary to malignancy. We encountered with a rare case in which metastasis to mandibular bone was the first clinical sign in the diagnosis of breast cancer without any radiographic findings. A 49-yr-old premenopausal woman, ...  Read More

Hematopathology
19. Orbital Metastasis from Rectal Adenocarcinoma- Report of a Rare Case

Subrata Pal; Kingshuk Bose; Abhishek Sharma; Mrinal Sikder

Volume 11, Issue 5 , Autumn 2016, , Pages 474-477

Abstract
  Colorectal carcinoma is a common malignancy in India as well as in world. Inspite of its high metastasizing ability to various organs and lymph node, orbital metastasis is exceptional. Very few cases have been reported in the world literature. We report orbital metastasis in a case of moderately differentiated ...  Read More

Hematopathology
20. Phyllodes Tumor of the Breast: 307 Treated Cases, the Largest Mexican Experience at a Single Breast Disease Institution

Eva Ruvalcaba-Limón; Josefina Jiménez-López; Verónica Bautista-Piña; Julio Ramírez-Bollas; Flavia Morales-Vásquez; Carlos Domínguez-Reyes; Antonio Maffuz-Aziz; Sergio Rodríguez-Cuevas

Volume 11, Issue 4 , Autumn 2016, , Pages 399-408

Abstract
  Background: Phyllodes tumor (PT) of the breast in Hispanic patients is more frequently reported with large tumors and with more borderline/malignant subtypes compared with other populations. The objective of this study was to describe characteristics of patients with PT and to identify differences among ...  Read More

Hematopathology
21. Rad51 Expression in Nasopharyngeal Carcinoma and Its Association with Tumor Reduction: A Preliminary Study in Indonesia

Dian Cahyanti; Lisnawati Rachmadi; Vally Wulani; Marlinda Adham

Volume 11, Issue 2 , Spring 2016, , Pages 155-160

Abstract
  Background: Overexpression of Rad51 protein in many tumor cells has been proven to increase radioresistance and can be related to the resistance of chemosensitivity of tumor cells. This preliminary study was conducted to determine the relationship between the Rad51 expression level in nasopharyngeal ...  Read More

Hematopathology
22. Granulomatous response with breast cancer in a developing country: A diagnostic dilemma!

Bushra Siddiqui; Shahbaz Habib Faridi; Veena Maheshwari; Mohammad Aslam; Kafil Akhtar

Volume 11, Issue 2 , Spring 2016, , Pages 171-175

Abstract
  Granulomatous response in association with breast cancer and within the cancer draining lymph nodes is an extremely rare phenomenon. Granulomatous inflammation is an immune response commonly seen against infectious agents and certain non-neoplastic conditions. The etiopathogenesis of granulomas associated ...  Read More

Hematopathology
23. The Report of KRAS Mutation and NRAS Wild-Type in a Patient with Thyroid Metastasis from Colon Cancer: a Rare Case Report

Mehrdad Payandeh; Masoud Sadeghi; Edris Sadeghi

Volume 11, Issue 1 , Winter 2016, , Pages 71-75

Abstract
  Colorectal cancer (CRC) metastasis to the thyroid gland is rare. Here wereport a 45 yr-old man in western Iran referred to Hematology Clinic, Kermanshah city, Iran in March 2014 with complaint of exertional dyspnea, multi-nodular goiter as well as complaint of exertional dyspnea, and multi-nodular goiter. ...  Read More