Volume 15 (2020)
Volume 14 (2019)
Volume 13 (2018)
Volume 12 (2017)
Volume 11 (2016)
Volume 10 (2015)
Volume 9 (2014)
Volume 8 (2013)
Volume 7 (2012)
Volume 6 (2011)
Volume 5 (2010)
Volume 4 (2009)
Volume 3 (2008)
Volume 2 (2007)
Volume 1 (2006)
26. The diagnostic value of TTF1, P63, HMWK [34βE12], CK7, and CD56 immunostaining in classification of lung carcinoma

Amir Hossein Jafarian; Masoumeh Gharib; Nema Mohammadian Roshan; Samaneh Sherafatnia; Abbas Ali Omidi; Sahar Bagheri

Volume 12, Issue 3 , Summer 2017, , Pages 195-201


  Background & objective: The histologic distinction of small cell from non-small cell lung carcinoma and correct identification of all subtypes of lung carcinoma are very important in treatment management. The main method for histologic classification of lung tumors is based on morphology. However, ...  Read More

27. Expression of Apoptosis Related and Proliferative Proteins in Malignant Lympho-Proliferative Disorders

Zeeba Jairajpuri; Rekha Ghai; Sumita Saluja; Sujala Kapur; K.T Bhowmick

Volume 12, Issue 3 , Summer 2017, , Pages 231-240


  Background & objective: The current study aimed to perform an immunohistochemical analysis of patterns of apoptotic and cell proliferative related protein expression in different histological grades and immune phenotypes of malignant lymphomas and other lymphoproliferative disorders Methods:This ...  Read More

28. Basic Characteristics of Oligodendrogliomas: The Shohada-e Tajrish Hospital Experience (2008-2014)

Mahsa Ahadi; Afshin Moradi; Azadeh Rakhshan; Alireza Arefian; Mitra Rafizadeh; Hanieh Zham

Volume 12, Issue 3 , Summer 2017, , Pages 241-247


  Background and Objectives: Gliomas are the most prevalent subgroup of primary brain tumors with a relatively high mortality. However, oligodendrogliomas have a better prognosis compared to other subtypes due to their sensitivity to chemotherapy. Considering the low incidence and the resulting lack of ...  Read More

29. The Core Needle and Surgical Biopsy Concordance to Detect Estrogen, Progesterone, and Her-2 Receptors in Breast Cancer: A Comparative Study

Fereshteh Ensani; Ramesh Omranipour; Isa Jahanzad; Azadeh Jafari; Shima Nafarzadeh; Pouyan Aminishakib

Volume 12, Issue 3 , Summer 2017, , Pages 202-208


  Background &Objectives: Evaluation of estrogen receptor (ER), progesterone receptor (PR), and (human epidermal growth factor receptor-2) Her-2 on core needle biopsies (CNBs) is increasingly in use to diagnosis early breast cancer, but its concordance with surgical excision (SE) is not well documented. ...  Read More

30. High Expression of Sphingosine Kinase 1 in Estrogen and Progesterone Receptors-Negative Breast Cancer

Azadeh Sadat Nazouri; omolbanin asadpour; Shahriar Dabiri; Bahram Pourseyedi; Mohamad reza Lashkarizadeh; Hamid Zeinalyneghad

Volume 12, Issue 3 , Summer 2017, , Pages 218-224


  Background & objective: Breast cancer is the leading cause of cancer related death in females. Sphingosine kinase 1 (SPHK1) and its product sphingosine-1-phosphate (S1P) are the essential key regulator molecules in breast cancer through their ability to promote cell proliferation, angiogenesis, cell ...  Read More

31. Benign Phyllodes Tumor With Cystic Squamous Metaplasia: A Cytohistological Correlation of a Rare Case

Indranil Chakrabarti; Priyanka Agarwala; Pranati Bera; Sankarshan Bhaduri

Volume 12, Issue 3 , Summer 2017, , Pages 291-294


  Background: Phyllodes tumors (PTs) are uncommon biphasic fibroepithelial neoplasms of the breast occurring in elderly females with a peak incidence between 45 and 49 years. Depending on various histological criteria, they are subdivided into benign, borderline, and malignant forms. Metaplastic changes ...  Read More

32. Correlation Between Subclinical Hypothyroidism and Dyslipidemia

Alireza Rastgooye Haghi; Mahdis Solhjoo; Mohammad Hossein Tavakoli

Volume 12, Issue 2 , Spring 2017, , Pages 106-111


  Background & Objective: Thyroid hormones have an important role in the regulation of lipid metabolism. Subclinical hypothyroidism (SCH), defined as a mild increase in thyroid-stimulating hormone (TSH) and normal level of thyroxine (T4), could be associated with altered lipid profile. The current ...  Read More

33. Testicular Biopsy in Males With Infertility: A Longitudinal Study

Sepideh Siadati; Hamid Shafi; Hossein Ghorbani

Volume 12, Issue 2 , Spring 2017, , Pages 177-182


  Background & objective: Regarding the importance of histologic examination of testicular biopsy for clinical planning of infertility, the current study was conducted to compare 2 separate histologic examination of testicular biopsy. Also, some cases with known fertility outcome were followed and ...  Read More

34. Evaluation of Nuclear Morphometry and Ki-67 Index in Clear Cell Renal Cell Carcinomas: a Five‌-Year Study

Sheela devi C S; Suchitha Satish; Veerendrasagar Sahukar

Volume 12, Issue 2 , Spring 2017, , Pages 150-157


  Background and objective: Clear Cell Renal Cell Carcinoma (CCRCC) is the most common adult renal neoplasm. Staging and grading of RCC are important predictors of survival. Fuhrman nuclear grading is widely used for CCRCC, the subjective nature of which has prompted more objective methods to evaluate ...  Read More

35. Possible Interrelationship of Inflammatory Cells in Dry Type Cutaneous leishmaniasis

Elham Taheri; Shahriar dabiri; Manzoomeh Shamsi Meymandi; Ebrahim Saedi

Volume 12, Issue 2 , Spring 2017, , Pages 119-127


  Background & Objective: There is a complicated interaction between leishmaniasis and the host immune cells, and also between the host immune cells. These interactions have fundamental effects on the outcome of the disease. The current study aimed at characterizing the number, distribution, co-localization, ...  Read More

36. The Relationship between Cytokeratins 7 and 20 Expression, and Prognostic Factors in Colon Adenocarcinoma: An Immunohistochemical Study

Mohammad Hossein Gheini; Noushin Jalayer Naderi

Volume 12, Issue 2 , Spring 2017, , Pages 94-98


  Background & Objective: The role of synchronized expression pattern of cytokeratin (CK) 7 and CK20 in the prognosis of colon adenocarcinoma is unclear. The current study aimed at determining the relationship between the expression of cytokeratins 7 and 20 and prognostic factors in colon adenocarcinoma. ...  Read More

37. Malignant Colorectal Polyps; Pathological Consideration (A review)

Bita Geramizadeh; Mahsa Marzban; David Owen

Volume 12, Issue 1 , Winter 2017, , Pages 1-8


  Background: Routine screening colonoscopy is on the rise and pathologists have to deal with the ever larger numbers of excised colonic polyps. It is very important to optimize the patients’ individual treatment and further surveillance. Pathologists play a critical role in management, as most of ...  Read More

38. Evaluation of Immunohistochemistry-Equivocal (2+) HER2 Gene Status in Invasive Breast Cancer by Silver DNA in Situ Hybridization (SISH) and its Association with Clinicopathological Variables

Zaidoon A. Musa; Ban J. Qasim; A.Wahab A.K. Al Shaikhly

Volume 12, Issue 1 , Winter 2017, , Pages 9-19


  Background and Objective:Determination of HER2 gene is crucial in breast carcinoma management and prognosis, as HER2 alterations are linked to a shorter disease-free period, overall survival and resistance to tamoxifen anti-estrogen therapy and other chemotherapy regimens, regardless of the nodal or ...  Read More

39. Alpha-Synuclein Expression in Acute Erythroleukaemia, Acute Megakaryoblastic Leukemia, and Normal Counterparts in Bone Marrow

Farid Kosari; Sanam Akbarzadeh; Hiva Saffar

Volume 12, Issue 1 , Winter 2017, , Pages 74-78


  Background:Alpha-synuclein is a member of synuclein family of proteins with unidentified function localized in the cytoplasm, mitochondria of neurons, and presynaptic nerve endings. Although it is found in the Lewy bodies in synucleinopathies and in Alzheimer’s disease, the protein could also be ...  Read More

40. Cervical Cancer and Genital Infections: Assessment of Performance and Validation in Human Papillomavirus Genotyping Assays in Iran, its Neighbouring Countries and Persian Gulf Area

Amir Sohrabi; Massoud Hajia

Volume 12, Issue 1 , Winter 2017, , Pages 35-44


  Background: The accuracy of diagnostic assays in Human Papillomavirus (HPV) genital infection and cervical cancer has remained a clinical challenge in diagnosis.  Evidence indicates that a large proportion of cervical cancer can be prevented through organized care for HPV and testing. Countries ...  Read More

41. Immunohistochemical and Electron Microscopic Study of the Inhibitory Effects of Olive Oil Polyphenol on Dexamethasone-Induced Apoptosis

Ali Reza Khalatbary; Behrooz Mohammadnegad; Ghazaleh Goudarzi; Ali Fazlollahpour Balef

Volume 12, Issue 1 , Winter 2017, , Pages 45-52


  Background: There is accumulating evidence that a polyphenol present in olive oil, oleuropein, has antioxidant, anti-inflammatory and anti-apoptotic effects. This study aimed at determining the anti-apoptotic effect of Oleuropein (Ole) on dexamethasone-induced apoptosis of mouse thymocytes. Method: Mice ...  Read More

42. Primary Stromal Sarcoma of Breast: A Rare Entity

Sanjay Kumar; Jyoti Sharma; Megha Ralli; Gurpreet Singh; Sonu Kalyan; Rajeev Sen

Volume 11, Issue 5 , Autumn 2016, , Pages 469-473

  Primary soft tissue sarcomas of the breast constitute less than 5% of all soft tissue sarcomas and less than 1% of malignant breast cancers. The rarity of this tumor limits most studies to small retrospective case reviews and case reports. Primary breast sarcomas are locally aggressive tumors as evidenced ...  Read More

43. Pre-Cancerous Lesions in the Oral and Maxillofacial Region: A Literature Review with Special Focus on Etiopathogenesis

Soussan Irani

Volume 11, Issue 4 , Autumn 2016, , Pages 303-322

  Many types of cancers develop in the oral and maxillofacial region. Squamous cell carcinoma is the most common cancer and constitutes over 90 percent of these tumors. Malignant transformation is a genetic process, which later makes a phenotyping change at the cellular level. Some cancers such as oral ...  Read More

44. Correlation of P16 (Ink4a) and CK17 to HPV (16E6+18E6) in Premalignant and Malignant Lesions of Uterine Cervix: A Clinicopathologic Study

Mohammed Chaloob; Alaa G. Hussein; Ban Qasim

Volume 11, Issue 4 , Autumn 2016, , Pages 377-390

  Background: This research was accomplished to evaluate the IHC expression of p16 (ink4a) and CK17 in low grade cervical intraepithelial lesions (LSIL), high grade cervical intraepithelial lesions (HSIL) and invasive cervical carcinomas and to assess their correlation to HPV (16E6+18E6). Methods: The ...  Read More

45. Hirschsprung Disease Diagnosis: Calretinin Marker Role in Determining the Presence or Absence of Ganglion Cells

Nasser Rakhshani; Mohammadreza Araste; Farid Imanzade; Mahshid Panahi; Fahimeh Safarnezhad Tameshkel; Masoud Reza Sohrabi; Mohammad Hadi Karbalaie Niya; Farhad Zamani

Volume 11, Issue 4 , Autumn 2016, , Pages 409-415

  Background: Hirschsprung disease is a complex genetic disorder of the enteric nervous system (ENS), often called congenital aganglionic megacolon and characterized by the absence of enteric neurons along a variable length of the intestine. The definitive diagnosis of Hirschsprung disease relies on histologic ...  Read More

46. Hairy Cell Leukemia in a Young Male: An Unusual Presentation

Manveen Kaur; Koushik Kar; Varsha Dalal; Fouzia Siraj

Volume 11, Issue 4 , Autumn 2016, , Pages 421-422

  Dear Editor-in-Chief A 28 yr male was presented in October 2015 at Medicine Outpatient Department, Safdarjung Hospital, New Delhi- India with generalized weakness, fever and cough for preceding 15 days. Clinicoradiologic examination revealed pallor, firm, non-tender splenomegaly measuring 13.7 cm and ...  Read More

47. Isolated Hepatic Tuberculoma – A Case Report

Biplab Biswas; Subrata Pal; DhrubaJyoti Moulick; Mrinal Sikdar

Volume 11, Issue 5 , Autumn 2016, , Pages 427-430

  Isolated hepatic tuberculoma is localized hepatic tuberculosis (TB) without bile duct involvement, which presents as solitary or multiple nodular mass lesion of liver mimicking a neoplastic lesion in radiological evaluation. Clinical presentation and biochemical tests for liver functions show non-specific ...  Read More

48. Middle Ear Salivary Gland Choristoma: A Case Report

Katayoun Ziari; Kamyab Alizadeh

Volume 11, Issue 5 , Autumn 2016, , Pages 461-464

  Salivary gland choristoma of the middle ear cavity is a very rare condition. These lesions are a result of a defective embryonic development and their adjacent structures may be associated with abnormalities. Here we report a case of salivary gland choristoma of the middle ear who presented to Be’sat ...  Read More

49. Bilateral Ovarian Clear Cell Carcinoma Arising in 17 Year Longstanding History of Bilateral Ovarian Endometriosis

Thin Thin Win; Nik Mohamed Zaki Nik Mahmood; Saung Oo Ma; Mazita Ismail

Volume 11, Issue 5 , Autumn 2016, , Pages 478-482

  Clear cell carcinoma of ovary is uncommon ovarian tumour that arises from surface epithelium of ovary. It has well-known association with ovarian endometriosis. We report here the first case of bilateral clear cell carcinoma of ovaries in a 40-year-old woman with a 17-year history of bilateral ovarian ...  Read More

50. Disseminated Skeletal Angiomatosis Initially Misdiagnosed As Metastatic Tumor: A Case Report

Fariba Binesh; Kazem Aghili; Marjan Hakiminia; Mohammad Reza Vahidfar; Roghayeh Masumi

Volume 11, Issue 5 , Autumn 2016, , Pages 443-447

  Disseminated angiomatosis, also referred to as cystic angiomatosis, is a generalized disease that involves bones and soft tissue. It is characterized by multifocal hemangiomatous lesions of the bones with possible visceral organ involvement. The clinical manifestations differ according to the site and ...  Read More