Volume 16 (2021)
Volume 15 (2020)
Volume 14 (2019)
Volume 13 (2018)
Volume 12 (2017)
Volume 11 (2016)
Volume 10 (2015)
Volume 9 (2014)
Volume 8 (2013)
Volume 7 (2012)
Volume 6 (2011)
Volume 5 (2010)
Volume 4 (2009)
Volume 3 (2008)
Volume 2 (2007)
Volume 1 (2006)
Gynecologic Pathology
1. Predicting Effects of Clinicopathological Variables on Her2 Gene Amplification by Chromogenic in situ Hybridization (CISH) in IHC Her2 (2+) Breast Cancer Patients; A Study from Iran

Mohammad Hashemi-Bahremani; Abdolali Ebrahimi; Mohaddese Fallahi

Volume 15, Issue 3 , Summer 2020, , Pages 217-224

http://dx.doi.org/10.30699/ijp.2020.110293.2172

Abstract
  Background & Objective: The her2 amplification plays an important role in breast cancer management. Therefore, there is a need for using supplementary molecular methods in IHC equivocal cases. Present study has been conducted to determine the effects of clinicopathological variables on her2 gene ...  Read More

2. The Core Needle and Surgical Biopsy Concordance to Detect Estrogen, Progesterone, and Her-2 Receptors in Breast Cancer: A Comparative Study

Fereshteh Ensani; Ramesh Omranipour; Isa Jahanzad; Azadeh Jafari; Shima Nafarzadeh; Pouyan Aminishakib

Volume 12, Issue 3 , Summer 2017, , Pages 202-208

http://dx.doi.org/10.30699/ijp.2017.25042

Abstract
  Background &Objectives: Evaluation of estrogen receptor (ER), progesterone receptor (PR), and (human epidermal growth factor receptor-2) Her-2 on core needle biopsies (CNBs) is increasingly in use to diagnosis early breast cancer, but its concordance with surgical excision (SE) is not well documented. ...  Read More

Gynecologic Pathology
3. The HER-2 as a Target Gene of Curcumin to Protect Hepatocytes Against the Arsenic-induced Carcinoma in Mice

Mahdi Ahadi; Vahid Naseh; Masoud Salehipour

Volume 12, Issue 2 , Spring 2017, , Pages 158-164

http://dx.doi.org/10.30699/ijp.2017.24874

Abstract
  Background & objective: The HER-2 gene is an important on co protein overexpressed in many types of cancers. The current study hypothesized that curcumin downregulates HER-2 and inhibits the signal transduction pathway of PI3K/Akt, MAPK, and activation of NFκB, which could be useful to treat ...  Read More

Hematopathology
4. Chromogenic in situ Hybridization Compared with Real Time Quantitative Polymerase Chain Reaction to Evaluate HER2/neu Status in Breast Cancer

Hossein Ayatollahi; Azar Fani; Ehsan Ghayoor Karimiani; Fateme Homaee; Arezoo Shajiei; Maryam Sheikh; Sepideh Shakeri; Seyyede Fatemeh Shams

Volume 12, Issue 2 , Spring 2017, , Pages 128-134

http://dx.doi.org/10.30699/ijp.2017.24870

Abstract
  Background and objective: The assessment of human epidermal growth factor receptor 2 (HER2) status has become of great importance in the diagnosis of breast cancer. The aim of this study was to investigate the diagnostic value of quantitative Polymerase Chain Reaction (qPCR) and Chromogenic In Situ Hybridization ...  Read More

5. Evaluation of Immunohistochemistry-Equivocal (2+) HER2 Gene Status in Invasive Breast Cancer by Silver DNA in Situ Hybridization (SISH) and its Association with Clinicopathological Variables

Zaidoon A. Musa; Ban J. Qasim; A.Wahab A.K. Al Shaikhly

Volume 12, Issue 1 , Winter 2017, , Pages 9-19

http://dx.doi.org/10.30699/ijp.2017.21544

Abstract
  Background and Objective:Determination of HER2 gene is crucial in breast carcinoma management and prognosis, as HER2 alterations are linked to a shorter disease-free period, overall survival and resistance to tamoxifen anti-estrogen therapy and other chemotherapy regimens, regardless of the nodal or ...  Read More