Krishnamurthy Jayashree; Divya Kota Nagappa
Volume 6, Issue 4 , September 2011, , Pages 212-215
Abstract
Bronchiolo-alveolar carcinoma with subcutaneous chest wall metastasis is a very rare presentation. A case of 36- year-old male with metastatic subcutaneous chest nodule of bronchiolo-alveolar carcinoma, diagnosed by fine needle aspiration cytology, is reported here. Cutaneous metastases are of ...
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Bronchiolo-alveolar carcinoma with subcutaneous chest wall metastasis is a very rare presentation. A case of 36- year-old male with metastatic subcutaneous chest nodule of bronchiolo-alveolar carcinoma, diagnosed by fine needle aspiration cytology, is reported here. Cutaneous metastases are of diagnostic importance because they may be the first manifestation of an undiscovered internal malignancy and indicates a poor prognostic sign. Fine needle aspiration cytology plays an important role in the early diagnosis of subcutaneous metastasis and helps to differentiate from other subcutaneous nodules like skin adnexal lesions, soft tissue tumors and inflammatory lesions.
Mitra Mehrazma1; Soraya Salehi; Shokrollah Yousefi; Selaheddin Delshad; Ahmad Jalilvand; Alireza Hasanpour
Volume 1, Issue 4 , September 2006, , Pages 155-160
Abstract
Background and Objective: Mediastinal masses in children are a heterogenous group of asymptomatic potentially life-threatening congenital, infectious, or neoplastic lesions that present complex diagnostic and therapeutic dilemmas. Materials and Methods: The clinical and laboratory features of 65 patients ...
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Background and Objective: Mediastinal masses in children are a heterogenous group of asymptomatic potentially life-threatening congenital, infectious, or neoplastic lesions that present complex diagnostic and therapeutic dilemmas. Materials and Methods: The clinical and laboratory features of 65 patients who had open biopsies in Ali-Asghar hospital over 11 years were reviewed. Results: Seventy-two percent of cases were male and 28% were female. The age varied between 2.5 months and 19 years. Eighty-four percent of lesions were malignant and 16% were benign. Neurogenic tumors were the most common (36.9%). In order of frequency the following lesions were the most common neuroblastoma (mostly in posterior mediastinum), Hodgkin’s and non-Hodgkin’s lymphoma (mostly in middle mediastinum), and malignant small round cell tumor (mostly in chest wall). Most patients were presented by fever (21.5%), dyspnea (20%) and cough (12%), especially in Hodgkin’s and non-Hodgkin’s lymphoma. Lymphadenopathy (29.2%) and hepatosplenomegaly (13.8%) were the most frequent clinical signs. Laboratory examination revealed anemia (29%), leukocytosis (35%), and high sedimentation rate (21.5%). Conclusion: The clinical presentation and laboratory findings of mediastinal and chest wall masses are often non-specific and are variable, but according to their clinical data (i.e. age) and location, only few important diagnoses should be considered.