Eswari Varadharajan; Shanmuga Priya; Geetha Prakash; Archana Mugundan; Praveen Easwaramurthi
Abstract
Mucinous carcinoma of the breast is a well-differentiated type of adenocarcinoma accounting for 2-5% of all breast cancers. Pure mucinous carcinoma of the breast has a favorable prognosis, usually seen in post-menopausal women. Neuroendocrine differentiation has been described in both in-situ and infiltrating ...
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Mucinous carcinoma of the breast is a well-differentiated type of adenocarcinoma accounting for 2-5% of all breast cancers. Pure mucinous carcinoma of the breast has a favorable prognosis, usually seen in post-menopausal women. Neuroendocrine differentiation has been described in both in-situ and infiltrating breast cancers .Mucinous carcinomas of the breast appear to have the greatest association with neuroendocrine differentiation. Chromogranin A and synaptophysin are specific immunohistochemical markers of neuroendocrine differentiation. We report a case of mucinous carcinoma of the breast with neuroendocrine differentiation in a 67-year-old female who was treated surgically in a classical manner. How to cite this article: Varadharajan E, Priya S, Prakash G, Mugundan A, Easwaramurthi P. Mucinous Carcinoma of the Breast with Neuroendocrine Differentiation. Iran J Pathol. 2015;10(3):231-6.
Sushma Ramraje; Sameer Ansari; Shantilal Sisodia; Niddhi Chaturvedi; Varsha Bhatia; Aparagita Goel
Volume 8, Issue 3 , July 2013, , Pages 199-203
Abstract
Mucinous carcinoma of the breast is a well differentiated, rare histological type of invasive ductal carcinoma, seen in oldest median age (69 years). We describe a case of a 60 yr old female with large right breast mass of 10 years duration with no nodal involvement. The reasons to present this case ...
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Mucinous carcinoma of the breast is a well differentiated, rare histological type of invasive ductal carcinoma, seen in oldest median age (69 years). We describe a case of a 60 yr old female with large right breast mass of 10 years duration with no nodal involvement. The reasons to present this case are 1) Because of its rarity. 2) Despite having a large tumour size, the axillary lymph node is not involved, hence rendering favourable prognosis. 3) Fine needle aspiration cytology can be used as an important tool in early detection of pure mucinous carcinoma of breast. 4) Careful clinical examination should be performed when suspicious for mucinous carcinoma because lymph node metastasis changes prognosis and treatment modalities .5) Pure mucinous carcinomas should be distinguished from mixed neoplasm, because the latter have a poorer prognosis that is most likely related to the extent of invasive carcinoma lacking extracellular mucin.