Infectious Diseases
Sedigheh Hantoushzadeh; Roya Saeednejad; Mamak Shariat; Raheleh Moradi
Abstract
Background & Objective: It was declared that COVID-19 might be more severe in symptomatic pregnant patients. This study was conducted to examine the pathological indices of the placenta in pregnant women who were diagnosed with COVID-19.Methods: A total of 20 COVID-19–positive mothers were ...
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Background & Objective: It was declared that COVID-19 might be more severe in symptomatic pregnant patients. This study was conducted to examine the pathological indices of the placenta in pregnant women who were diagnosed with COVID-19.Methods: A total of 20 COVID-19–positive mothers were enrolled in this study. Detailed placental pathology findings were compared between subjects based on the history of abortion or occurrence of preterm delivery, hypertension, and diabetes.Results and Conclusion: Intervillositis was the most frequent abnormality of the placenta. There was also a significant association between abortion history and maternal vascular malperfusion (MVM; P=0.02). The placental abnormalities were found to be increased in women with COVID-19, regardless of maternal comorbidities. Further studies are needed to compare the placental pathology between COVID-19–positive women and healthy women.
Beuy Joob; Viroj Wiwanitkit
Volume 11, Issue 3 , July 2016, , Pages 301-302
Abstract
Dear Editor-in-Chief The recent report on “The Adverse Effects of Pregnancies Complicated by Hemoglobin H (HBH) Disease” is very interesting (1). Rabiee et al. reported a pregnant case complicated with HBH disease. Indeed, this problem might not common in the Middle East but it is very ...
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Dear Editor-in-Chief The recent report on “The Adverse Effects of Pregnancies Complicated by Hemoglobin H (HBH) Disease” is very interesting (1). Rabiee et al. reported a pregnant case complicated with HBH disease. Indeed, this problem might not common in the Middle East but it is very common in Southeast Asia. The authors hereby would like to share the experience on this topic. In the recent report by Tongsong et al. (2), the maternal outcomes of normal mothers and those with HBH disease were not different. The common identified problems are fetal growth restriction, preterm birth and low birth weight (2).
Maryam Rabiee; Jalal-Aldin Shams; Nafiseh Zafargandie
Abstract
Hemoglobin (Hb) H disease is a moderate form of α- thalassemia resulting from various genetic defects. HbH disease is not necessarily a benign disorder as has been generally thought. We present hereby a 25- year-old Iranian pregnant woman whom referred to our hospital for blood transfusion. She ...
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Hemoglobin (Hb) H disease is a moderate form of α- thalassemia resulting from various genetic defects. HbH disease is not necessarily a benign disorder as has been generally thought. We present hereby a 25- year-old Iranian pregnant woman whom referred to our hospital for blood transfusion. She exhibited the clinical and hematological manifestation of HbH disease. Her father carries a common α-thalassemia deletion while her mother was normal in the hematological profile. The object of this report was to provide information about pregnancies affected by HbH disease.
Shirin Niroumanesh; Fatemeh Mirzaei
Volume 4, Issue 4 , September 2009, , Pages 182-185
Abstract
Background and Objectives: The diagnosis of pregnancy associated adnexal masses is rising due to routine utilization of sonography in prenatal care. The purpose of this study was to describe pregnancy associated adnexal masses over a period of 10 years. Patients and Methods: A retrospective study was ...
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Background and Objectives: The diagnosis of pregnancy associated adnexal masses is rising due to routine utilization of sonography in prenatal care. The purpose of this study was to describe pregnancy associated adnexal masses over a period of 10 years. Patients and Methods: A retrospective study was reviewed hospital records of all pregnant women with adnexal mass that underwent surgical resection in Mirza Kuchak Khan Hospital in Tehran from January 1996 to March 2006. The collected data included maternal age, parity, gestational age at diagnosis, surgery and delivery, presenting symptoms and treatment. The pregnancy outcome complications and histological findings were reviewed. Results: Totally 29220 deliveries were performed in our institution; adnexal masses were detected in 0.01% of pregnancies. Antepartum surgery was performed in 4 (10.3%) patients. The mean gestational age at delivery in patients undergoing surgery during pregnancy was 36 weeks (ranged 36-37 weeks) while in patients with cystectomy during cesarean delivery was 38 weeks (range: 33-40) (P=0.04). There were no statistically significant differences in birth weight between the patients undergoing surgery during pregnancy and those with surgery at cesarean delivery (P=0.176). The mean cyst diameter was 11 cm (range 4-16 cm) for patients operated during pregnancy while it was 4 cm (2.5-12 cm) for those undergoing surgery during cesarean delivery (P=0.006). The most common diagnosis was benign serous cyst (23.1%) followed by benign Dermoid cyst (20.5%). Conclusion: Patients undergoing laparotomy for adnexal mass during pregnancy had higher risk of preterm labor but there were no difference in birth weight.
Ali Jazayeri Moghadas; Gholamreza Irajian
Volume 4, Issue 3 , June 2009, , Pages 105-108
Abstract
Background and Objectives: Urinary tract infection is one of the most common bacterial infections in the human population, and more frequent infection during pregnancy. With notice to this point that most of urinary tract infections during pregnancy are asymptomatic, they could lead to serious ...
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Background and Objectives: Urinary tract infection is one of the most common bacterial infections in the human population, and more frequent infection during pregnancy. With notice to this point that most of urinary tract infections during pregnancy are asymptomatic, they could lead to serious complications such as prematurity, low-birth weight, hypertension, and higher fetal mortality rates ifuntreated. This study was aimed to determine the prevalence of asymptomatic bacteriuria, bacterial agents and their antibiotic susceptibility pattern in pregnant womenattendingSemnan public health centers during 2007-8. Patients and Methods: In this descriptive cross sectional study,pregnant women attending Semnan public health centers during May 2007 and June 2008 were investigated. Clean catch mid stream urine samples were collected and cultured on Eosin Metylene Blue agar and Blood agar by calibrated loop method. Suspected colonies were identified, antibiotic susceptibility test was done. Results: Of 297 samples, 10 (3.3%) were positive for asymptomatic urinary tract infection. The dominant bacterial isolate was Escherichia coli (70%). The antibiotic susceptibility was observed to ciprofloxacin, ceftazidime and cefotaxime (80%), the most resistance was amoxicillin- clavulanic acid (90%). Conclusion: Frequency of asymptomatic UTI in pregnant women in this study is significantly lower than similar studies. Antibiotic susceptibility rate to using antibiotics do not show significant differences with most other studies.
Nahid Mostaghel; Elham Tavanayanfar; Elham Neisani Samani
Volume 3, Issue 2 , March 2008, , Pages 51-54
Abstract
Background and Objective: Hypertensive disorders complicating pregnancy are common and from one of the deadly triad, along with hemorrhage and infection that contribute greatly to prenatal and maternal morbidity and mortality in the developing countries. This study was designed to investigate ...
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Background and Objective: Hypertensive disorders complicating pregnancy are common and from one of the deadly triad, along with hemorrhage and infection that contribute greatly to prenatal and maternal morbidity and mortality in the developing countries. This study was designed to investigate the relationship between maternal hypothyroidism and pre-eclampsia. Materials and Methods: In a prospective case-control study, maternal thyroid hormonal status was evaluated in 132 pregnant women with gestational hypertension and compared to controls. Results: It was found out that 23 women (7.3%) had pregnancy-induced hypertension (PIH), 45 women (14.3%) had mild pre-eclampsia, 62 women (19.7%) had severe pre-eclampsia and 2 (0.6%) had eclampsia. Mean of thyroid stimulating hormone (TSH) levels was not significantly higher in pre-eclamptic group as compared to controls (p>0.05). Conclusion: Maternal hypothyroidism might not be associated with pre-eclampsia
Hossein Ayatollahi; Maliheh Hasanzade; Mahdi Farzadnia; Mahdi Khabbaz Khoob; Atefeh Rahmanian
Volume 2, Issue 3 , June 2007, , Pages 100-104
Abstract
Background and Objective: The aim of this study was to determine the level of plasma high sensitive c-reactive protein (hs-CRP) in preeclampsia and to compare hs-CRP levels between normal pregnant women, mild preeclamptic, and severe preeclamptic women. Materials and Methods: Serum hs-CRP levels were ...
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Background and Objective: The aim of this study was to determine the level of plasma high sensitive c-reactive protein (hs-CRP) in preeclampsia and to compare hs-CRP levels between normal pregnant women, mild preeclamptic, and severe preeclamptic women. Materials and Methods: Serum hs-CRP levels were investigated in 40 cases of normal pregnant women, 37 cases with mild preeclampsia and 38 cases with severe preeclampsia in the third trimester of pregnancy. Venous blood samples were collected at admission to the hospital at least 6h before delivery for measurement of hs-CRP by immuno turbidometric method. The student t-test was used for comparison of proportions. Results: There were significant difference in the means serum hs-CRP between normal pregnant women and mild preeclamptic women (P<0.05). Serum concentration of hs-CRP were significantly higher in severe prceclampsia (p<0.05) than normal pregnancy. There were also significant differences in hs-CRP levels between mild and severe preclampsia (P<0.05). Conclusion: We found higher levels of hs-CRP in mild and severe preeclampsia than normal pregnancy and also these results suggest that hs- CRP are increased more in severe preeclamsia than mild preeclampsia , and may be useful in prediction and diagnosis of the severity of preeclampsia.