Diagnostic Pathology
sora yaari; Viroj Wiwanitkit
Volume 13, Issue 4 , October 2018, , Pages 479-479
Abstract
Dear Editor, erythrocyte sedimentation rate (ESR) is a useful basic clinical pathology laboratory investigation. It can be helpful in diagnosis and follow-up of several diseases. At present, a new automated method with proven reliability is available for ESR test (1). Here, the authors report on ...
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Dear Editor, erythrocyte sedimentation rate (ESR) is a useful basic clinical pathology laboratory investigation. It can be helpful in diagnosis and follow-up of several diseases. At present, a new automated method with proven reliability is available for ESR test (1). Here, the authors report on observation on a laboratory experiment to test the effect of zinc nanoparticles on ESR results. The total of 100 blood samples was used in the experiment. Each sample was divided into two parts. One part was directly measured for ESR and the other part was added by 1 droplet of zinc nanoparticles solution then exposed to ESR measurement. All ESR measurements were done using the same automated ESR analyzer; MicroSed SR-system, in the same ISO15189 accredited clinical laboratory at the same time, place and condition. The ESR results showed a difference in ESR values between two groups. The ESR values for the groups with and without zinc nanoparticles were equal to 25.6 + 7.2 and 10.7 + 3.4 mm/hr, respectively. Therefore, zinc nanoparticles can interrupt the ESR test conducted by automated analyzer. This observation was similar to the recent report which showed nanoparticles can alter the result of lipid profile test (2). Therefore, due to the widely use of nanoparticle substances, practitioners must consider the effect of nanoparticles interference in the interpretation of ESR results.
Mahboubeh Mirhosseini; Fatemeh Barzegari Firouzabadi
Volume 9, Issue 2 , April 2014, , Pages 99-106
Abstract
Background & Objectives: Nanotechnology is one of great important part of technology. Nanoparticles can be used in different applications for industrial, medical, military and personal use. The objectives of this study were preparation of Polystyrene/ZnO nanocomposite films via a simple method and ...
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Background & Objectives: Nanotechnology is one of great important part of technology. Nanoparticles can be used in different applications for industrial, medical, military and personal use. The objectives of this study were preparation of Polystyrene/ZnO nanocomposite films via a simple method and investigation of antibacterial activity of them.
Methods: Polystyrene /ZnO nanoparticle (PS/nano-ZnO) composite films were prepared via simple method with 0, 0.1, 1 and 2.5% wt concentration of ZnO and characterized by scanning electron microscopy (SEM). The antibacterial properties of the product were investigated against Listeria monocytogenes, Escherichia coli, Staphylococcus aureus and Bacillus cereus.
Results: The survival ratio of L. monocytogenes, E. coli, S. aureus and B. cereus decreased with increase of ZnO content on PS/nano-ZnO composite films and the best antibacterial activity was obtained with 2.5% wt ZnO-PS composite films for all bacteria. Results show the larger sensitivity of the S. aureus compared to other bacteria.
Conclusion: The treated fabric with ZnO NP indicates significant improve for antibacterial properties for polystyrene fabric.
Saeed Rezaei-Zarchi; Aisha Javed; Madiha Javeed Ghani; Safieh Soufian; Fatemeh Barzegari Firouzabadi; Abdolmajid Bayanduri Moghaddam; Seyed Hossein Mirjalili
Volume 5, Issue 2 , March 2010, , Pages 83-89
Abstract
Background: and Objectives:The aim of this study was to detect the antibacterial properties of 0.01, 0.5 and 1% nano-TiO2 and -CdO against E. coli. Materials and Methods: E. coli was cultured in liquid and agar nutrient medium to evaluate the antibacterial effects of 0.01, 0.05 and 1% of both ...
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Background: and Objectives:The aim of this study was to detect the antibacterial properties of 0.01, 0.5 and 1% nano-TiO2 and -CdO against E. coli. Materials and Methods: E. coli was cultured in liquid and agar nutrient medium to evaluate the antibacterial effects of 0.01, 0.05 and 1% of both nano-TiO2 and -CdO via the optical density (OD) and log CFU/ml measurements. Results: Non-significant effect was seen for 0.01% of both nano-specimens. While, 0.05 and 1% of both nanoparticles showed considerably decreased bacterial number. A 4.5 and 1.9 times decrease in the OD value was found in the presence of 1 and 0.5% nano-TiO2, respectively(P< 0.001). 1.5 and 3.3 times decreased OD was seen in the presence of 0.5 and 1% nano-CdO, respectively, as compared to control (P<0.001). In the second study, 6.3 log CFU/ml of E. coli were present in the cultures treated with 1% nano-TiO2 and CdO at 4 ºC in water. Control E. coli cells survived for 12 days while complete cell death was seen when 1% nano-TiO2 was applied for 13 hours as compared to 1% nano-CdO, which showed complete cell death after 15 hours. In the third study, E. coli was grown in the agar medium with and without both nanoparticles and suppressed growth (4.5 and 5.6 times; P<0.001) was seen in the presence of 1% nano-CdO and -TiO2, respectively. Conclusion: In spite of the fact that both nanoparticles showed bactericidal activity, nano-TiO2 has proven to be more efficient antibacterial agent as compared to nano-CdO.
