Shilpa Bairwa; Bhawna Sethi; Pawan Singh; Ashok Sangwaiya; Shivani Kalhan
Volume 13, Issue 4 , October 2018, , Pages 471-473
Abstract
A choriostoma is an aggregate of microscopically normal cells or tissues which occurs in an aberrant location. It follows a benign course, rarely seen in head and neck region. A choriostoma of the palatine tonsil is very rare; less than 10 cases were reported till date. A 11-year-old male referred to ...
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A choriostoma is an aggregate of microscopically normal cells or tissues which occurs in an aberrant location. It follows a benign course, rarely seen in head and neck region. A choriostoma of the palatine tonsil is very rare; less than 10 cases were reported till date. A 11-year-old male referred to ENT OPD with chronic tonsillitis and underwent tonsillectomy. The histopathological examination revealed the unexpected presence of cartilage and bone in both tonsils.
Sethi Bhawna; Arora Bharti; Kumar Yogesh; Aggarwal Reena
Volume 8, Issue 1 , January 2013, , Pages 1-8
Abstract
Background& Objectives: Inspite of intensive worldwide efforts to reduce its transmission, malaria remains the most serious and widespread protozoal infection of humans. It is a protozoan disease transmitted by the bite of infected female anopheles mosquito. Malaria has long featured prominently ...
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Background& Objectives: Inspite of intensive worldwide efforts to reduce its transmission, malaria remains the most serious and widespread protozoal infection of humans. It is a protozoan disease transmitted by the bite of infected female anopheles mosquito. Malaria has long featured prominently in the grey area between parasitology and hematology. This study has been performed to evaluate various hematological alterations in patients infected with malaria and to add more detailed information, especially from these highly affected zones.
Materials and methods: A two-year, hospital-based study was conducted and hematologic profiles of 200 persons infected with malaria (Plasmodium vivax or Plasmodium falciparum) infection, were examined and the results were compared with standard normal values.
Results: One-hundred-ninety-six patients were infected with Plasmodium vivax, three with Plasmodium falciparum, and one was infected with both. Patients with parasitemia tended to have significantly lower platelets, hemoglobin, white blood cell and red blood cell counts, blood indices and hematocrit than normal. Thrombocytopenia is identified as a key indicator of malaria in these febrile patients.
Conclusion: Anemia and thrombocytopenia are the classical changes. Changes in the white blood cells are less dramatic, may vary due to variable size and type of cases, variability of the species, and geographical differences.
Marwah Nisha; Sethi Bhawna; Gupta Sumiti; Duhan Amrita; Singh Sunita; Sen Rajeev
Volume 6, Issue 4 , September 2011, , Pages 179-186
Abstract
Background and Objectives: In spite of large number of studies conducted so far, sudden cardiac death remains an enigma and relative importance of acute coronary events as a trigger of sudden death is currently unclear. An autopsy study of heart was therefore planned to observe various histomorphological ...
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Background and Objectives: In spite of large number of studies conducted so far, sudden cardiac death remains an enigma and relative importance of acute coronary events as a trigger of sudden death is currently unclear. An autopsy study of heart was therefore planned to observe various histomorphological cardiac changes, and to determine the frequency association of acute coronary events and myocardial infarction with sudden death.
Material and Methods: A prospective randomized study of two hundred autopsied hearts submitted for postmortem analysis was conducted in the Department of Pathology, PGIMS Rohtak over a period of two and a half years from June 2007 to December 2009. The hearts were examined grossly and microscopically to observe various histomorphological changes and findings were correlated clinically.
Results: Out of 200 autopsied hearts, 142 (71%) revealed coronary artery atherosclerosis in one or more vessels. Maximum number of cases (32.5%) revealed three vessel diseases. Significant atherosclerosis (>50% reduction in diameter) was present in 125 (62.5%) cases, while 58 cases (29%) revealed no observable atherosclerotic change. One hundred twenty cases could be categorized under sudden cardiac death, 15.83% revealed changes of acute MI, 40% of healed MI and 44% revealed no change.
Conclusion: The ischemic heart disease was found to be the leading cause of death with coronary atherosclerosis being the most significant pathogenetic mechanism and three vessel disease the most common pattern of involvement. Acute coronary events (occlusive or non-occlusive thrombus/ plaque rupture/ haemorrhage) were observed in only 16% of the cases of sudden coronary death.