Gireesha Rawal; Sufian Zaheer; Amit Yadav; Indrani Dhawan
Volume 13, Issue 4 , October 2018, , Pages 474-478
Abstract
Malignant fibrous histiocytoma (MFH) is one of the most common types of soft tissue sarcomas in adults. Distant metastases are developed in 30–40% of patients with MFH, with the most common site being the lung. However, metachronous MFH has not been reported previously in literature. This report ...
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Malignant fibrous histiocytoma (MFH) is one of the most common types of soft tissue sarcomas in adults. Distant metastases are developed in 30–40% of patients with MFH, with the most common site being the lung. However, metachronous MFH has not been reported previously in literature. This report describes a case of a 30-year-old man, who had two metachronous thigh tumors, both of which were confirmed to be MFH on histopathology and immunohistochemistry evaluations. A contemporary multidisciplinary approach to therapy including surgery, radiation and chemotherapy was advocated. Two primary sites of MFH raised the possibility of a genetic abnormality that could predispose such a patient to develop multiple primary sites of the same tumor.
S Shamshad Ahmad; Sufian Zaheer; Khaliqur Rahman; Latif Zafar Jilani; Amit Kumar; Mohd Jaseem Hassan; Rana K Sherwani
Volume 8, Issue 2 , April 2013, , Pages 119-122
Abstract
Ewing's sarcoma (ES) is a highly malignant neoplasm of childhood and adolescence seen commonly in both axial and appendicular skeleton but uncommonly in acral region. Ewing’s tumor in the hand is extraordinarily rare. Radiological features are variable and can mimic other common lesions. We present ...
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Ewing's sarcoma (ES) is a highly malignant neoplasm of childhood and adolescence seen commonly in both axial and appendicular skeleton but uncommonly in acral region. Ewing’s tumor in the hand is extraordinarily rare. Radiological features are variable and can mimic other common lesions. We present a case of 13 year old female, with complaints of pain and swelling in right hand, which on X-ray showed periosteal reaction, giving a sun burst appearance and provisional diagnosis of osteosarcoma was made. The patient was operated and histopathological diagnosis of ES was confirmed. Histopathological examination remains the mainstay of diagnosis, supported by immunochemistry and cytogenetic studies. Surgical extirpation with chemotherapy is the therapeutic regimen of choice. We intend to report this case, because it is very rare location and the radiological features can mimic other lesions which commonly occur in this location like chronic osteomyelitis so it can be easily missed especially at preliminary evaluations.
Nishat Afroz; Sufian Zaheer; Nazoora Khan; M Amanullah Khan
Volume 5, Issue 4 , September 2010, , Pages 207-207
Abstract
While carcinoma of breast is common condition, stromal sarcomas are rare tumors of breast, amongst which fibrosarcoma accounts for 16% of cases. Only a few case reports are available in the international literature. We report a case of fibrosarcoma of breast, which presented as an un-encapsulated mass ...
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While carcinoma of breast is common condition, stromal sarcomas are rare tumors of breast, amongst which fibrosarcoma accounts for 16% of cases. Only a few case reports are available in the international literature. We report a case of fibrosarcoma of breast, which presented as an un-encapsulated mass in the right breast of a 60-year-old female. This case was diagnosed after exclusion of all possible differential diagnoses namely metaplastic carcinoma, cystosarcoma phylloides and other sarcomas of breast owing to its different histogenesis and prognostic behavior, in the light of detailed histopathological examination and immunohistochemical profile.