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Biology & Genetic
1. Relationship Between PIK3CA Amplification and P110α and CD34 Tissue Expression as Angiogenesis Markers in Iranian Women with Sporadic Breast Cancer

Shadi Hosseini; Farkhondeh Behjati; Maryam Rahimi; Nazanin Taheri; Hamid Reza Khorram Khorshid; Fatemehte Aghakhani Moghaddam; Saghar Ghasemi Frouzabadi; Masoud Karimlou; Fereidoon Sirati; Elahe Keyhani

Volume 13, Issue 4 , Autumn 2018, , Pages 447-453

Abstract
  Background and Objective: The PI3K/AKT/mTOR pathway is known to play an important role in regulating angiogenesis both in normal and breast cancer (BC) tissues. PIK3CA amplification was reported in various malignancies, including approximately 10% of BC cases. The aim of this study was to identify the ...  Read More