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High Expression of Sphingosine Kinase 1 in Estrogen and Progesterone Receptors-Negative Breast Cancer

Azadeh Sadat Nazouri; omolbanin asadpour; Shahriar Dabiri; Bahram Pourseyedi; Mohamad reza Lashkarizadeh; Hamid Zeinalyneghad

Volume 12, Issue 3 , July 2017, , Pages 218-224

https://doi.org/10.30699/ijp.2017.25049

Abstract
  Background & objective: Breast cancer is the leading cause of cancer related death in females. Sphingosine kinase 1 (SPHK1) and its product sphingosine-1-phosphate (S1P) are the essential key regulator molecules in breast cancer through their ability to promote cell proliferation, angiogenesis, cell ...  Read More