Volume 19 (2024)
Volume 18 (2023)
Volume 17 (2022)
Volume 16 (2021)
Volume 15 (2020)
Volume 14 (2019)
Volume 13 (2018)
Volume 12 (2017)
Volume 11 (2016)
Volume 10 (2015)
Volume 9 (2014)
Volume 8 (2013)
Volume 7 (2012)
Volume 6 (2011)
Volume 5 (2010)
Volume 4 (2009)
Volume 3 (2008)
Volume 2 (2007)
Volume 1 (2006)
Molecular Pathology
Different Isoforms of PML-RARA Chimeric Protein in Patients with Acute Promyelocytic Leukemia: Survival Analysis per Demographic Characteristics, Clinicohematological Parameters, and Cytogenetic Findings

Sarah Siahbani; Akbar Safaie; Masoumeh Faghih; Marzieh Hosseini; Afsaneh Fendereski; Behnaz Valibeigi; Ahmad Monabati

Volume 18, Issue 4 , October 2023, , Pages 456-475

https://doi.org/10.30699/ijp.2023.2007229.3145

Abstract
  Background & Objective: Acute Promyelocytic Leukemia (APL) is a medical emergency with potentially fatal complications. APL primarily results from a chromosomal translocation (t(15;17)(q22;q21)), leading to the formation of the PML-RARA fusion gene with three possible isoforms. This study aims to ...  Read More

Hematopathology
P53 IHC Result as a Prognostic Tool in MDS

Alireza Rezvani; Ahmad Monabati; Zahra Kargar; Akbar Safaie; Mahdi Mahmoodzadeh; Hamideh Moosapour; Marzieh Hosseini; Soleiman Kheiri; Elham Taheri

Volume 18, Issue 3 , July 2023, , Pages 327-334

https://doi.org/10.30699/ijp.2023.1971023.2991

Abstract
  Background & Objective: Some of the patients with myelodysplastic syndrome (MDS) are categorized as good prognosis based on the Revised International Prognostic Scoring System (IPSS-R). However, these patients may have poor clinical outcomes. It seems that the current diagnostic tools and IPSS-R ...  Read More

Molecular Pathology
A Preliminary Sequence Analysis of the Epstein-Barr Virus Nuclear Antigen 1 (EBNA1) Carboxy-Terminal Region in Cervical and Ovarian Cancers

Fatemeh Hoseini Tabatabaie; Seyed Younes Hosseini; Seyed Mohammad Ali Hashemi; Akbar Safaie; Jamal Sarvari

Volume 18, Issue 1 , January 2023, , Pages 24-32

https://doi.org/10.30699/ijp.2023.551761.2872

Abstract
  Background & Objective: Epstein-Barr virus nuclear antigen-1 (EBNA1) is one of the most important proteins of Epstein-Barr virus (EBV) that might be mutated in various related cancers. The purpose of this study was to compare EBNA1 mutations in the C-terminal region between patients with cervical ...  Read More

Dermatopathology
BRAF Mutation Analysis in Primary Acral Melanoma of 41 Cases from South of Iran

Fatemeh Sari Aslani; Akbar Safaee; Mozhgan Akbarzadeh Jahromi; Leila Karami

Volume 16, Issue 4 , August 2021, , Pages 370-375

https://doi.org/10.30699/ijp.2021.139458.2523

Abstract
  Background & Objective: Acral melanoma (AM) is a common type of cutaneous melanoma that occurs in the skin of the palms, soles, and nail beds. This malignancy, like other types of cancer, has different genetic alterations. To date, despite decades of research the roles of oncogenic BRAF mutations ...  Read More

Hematopathology
JAK2, CALR, and MPL Mutation Profiles in BCR-ABL Negative Myeloproliferative Neoplasms, a Referral Center Experience in the Middle East

Moeinadin Safavi; Ahmad Monabati; Akbar Safaie; Maryam Mirtalebi; Masoumeh Faghih

Volume 16, Issue 2 , April 2021, , Pages 190-194

https://doi.org/10.30699/ijp.2021.136458.2495

Abstract
  Background: This study was conducted to evaluate the frequency of JAK2, CALR and MPL mutations in with BCR-ABL myeloproliferative neoplasms and their association with demographic data and hematologic parameters in a referral center, in the Middle East. Methods: Seventy-one patients with BCR-ABL negative ...  Read More

Gynecologic Pathology
Association of Human Papilloma Virus and Epstein-Barr Virus with Ovarian Cancer in Shiraz, Southwestern Iran

Mohammad Reza Shokouh; Akbar Safaie; Afagh Moattari; Jamal Sarvari

Volume 15, Issue 4 , October 2020, , Pages 292-298

https://doi.org/10.30699/ijp.2020.119681.2306

Abstract
  Background & Objective:  Ovarian cancer is one of the most common cancers amongst women. The association of Human papillomavirus (HPV) and Epstein-Barr virus (EBV) with ovarian cancer is inconclusive; therefore, the aims of this study were to evaluate the frequency of HPV and EBV in malignant, ...  Read More

Breast Pathology
Cytoplasmic Her2/neu immunohistochemical staining in breast cancer; From a molecular point of view

Akbar Safaei; Ahmad Monabati; Maral Mokhtari; Mehdi Montazer

Volume 14, Issue 3 , August 2019, , Pages 270-271

https://doi.org/10.30699/ijp.2019.76630.1732

Abstract
  The most widely used guideline for the breast cancer biomarker assessment and reporting (the 2013 ASCO/CAP guideline) does not state the unusual occurrence of cytoplasmic Her2/neu staining (1, 2). We recently encountered a T2N1Mx ductal adeno-carcinoma which consisted of two dissimilar tumor cell populations. ...  Read More

Molecular Pathology
Evaluation of the CD123 Expression and FLT3 Gene Mutations in Patients with Acute Myeloid Leukemia

Freidoon Solhjoo; Akbar Safaie; Ahmad Monabati; Maral Mokhtari; Moeinadin Safavi

Volume 13, Issue 4 , October 2018, , Pages 438-446

Abstract
  Background and Objective: Identification of cytogenetic and molecular changes plays an important role in acute myeloid leukemia (AML) patients. Thus, they are used in classification, prognosis and treatment of the disease. The CD123 expression and FLT3 gene mutations are also the variations that may ...  Read More