Volume 15 (2020)
Volume 14 (2019)
Volume 13 (2018)
Volume 12 (2017)
Volume 11 (2016)
Volume 10 (2015)
Volume 9 (2014)
Volume 8 (2013)
Volume 7 (2012)
Volume 6 (2011)
Volume 5 (2010)
Volume 4 (2009)
Volume 3 (2008)
Volume 2 (2007)
Volume 1 (2006)
51. Comparing the Efficacy of Virtual and Conventional Methods in Teaching Practical Pathology to Medical Students

Alireza Abdollahi; Samaneh Salarvand; Hiva Saffar

Volume 13, Issue 2 , Spring 2018, , Pages 108-112


  Electronic learning introduces a teaching device for deeper and more efficient learning. A study was conducted by the Pathology Department of Tehran University of Medical Sciences, Tehran, Iran. The topic of practical pathology was selected earlier based on the curriculum. High-quality digital images ...  Read More

52. Prognostic Value of EVI1 Expression in Pediatric Acute Myeloid Leukemia: A Systematic Review

Mohammad Hadi Sadeghian; Zahra Rezaei dezaki

Volume 13, Issue 3 , Summer 2018, , Pages 294-300

  Acute myeloid leukemia (AML) as a distortion of blood cells involves the differentiation of hematopoietic stem cells. Several studies established the irregular overexpression of specific genes is a common finding in patients with AML. The ectopic viral integration site-1 (EVI1) gene is a proto-oncogene ...  Read More

53. The Comparison Between Microwave and Autoclave as Antigen Retrieval Methods for Immunohistochemical Detection of CD15 and CD30 in Hodgkin’s Lymphoma

Farid Kosari; Fatemeh Ghaffari

Volume 13, Issue 4 , Autumn 2018, , Pages 390-396

  Background and Objective: Hodgkin's lymphoma is a potentially curable hematologic malignancy with difficulty in its diagnosis especially in atypical cases even in expert hands. Today, immunohistochemistry plays a significant role in the diagnosis of it especially applying the anti-CD15 and anti-CD30 ...  Read More

Molecular Pathology
54. Epidermal Growth Factor Receptor (EGFR) Gene Mutation Analysis in Adenocarcinoma of Lung, the First Report from Iran

Sahand Mohammadzadeh; Zahra Jowkar; Mitra Mirzaee; Bita Geramizadeh

Volume 14, Issue 1 , Winter 2019, , Pages 1-7


  Background and Objective: Epidermal growth factor receptor (EGFR) gene mutation, especially in exons 18 to 21, is an important predictor of the response rate of lung adenocarcinoma to tyrosine kinase inhibitors. There are variable reports from Asian and European countries, as well as North America, about ...  Read More

Molecular Pathology
55. Evaluation of Cyclooxygenase-2 Expression in Association with Clinical-Pathological Factors in Malignant Melanoma

Amir Hossein Jafarian; Nema Mohammadian Roshan; Masoumeh Gharib; Vahid Moshirahmadi; Aida Tasbandi; Amir Ali Ayatollahi; Hossein Ayatollahi

Volume 14, Issue 2 , Spring 2019, , Pages 96-103


  Background and Objective: The primary goal of this study is to develop a rigorous understanding ofthe correlation between COX-2 expression and malignant melanoma prognostic factors. Material and Methods: In this cross-sectional study, we analyzed 60 cases of cutaneous malignant melanoma. The related ...  Read More

56. Secondary Use of Laboratory data: Potentialities and Limitations

Massoud Hajia

Volume 14, Issue 3 , Summer 2019, , Pages 188-192


  Clinical databases have been developed in recent years especially during the course of all medical concerns including laboratory results. The information produced by the diagnostic laboratories have great impact on health care system with various secondary uses. These uses are sometimes as publishing ...  Read More

57. Low Expression of Occludin in the Melanoma Patients

Pouri Salehi; Farzaneh Tafvizi; Kambiz Kamyab Hesari

Volume 14, Issue 4 , Autumn 2019, , Pages 272-278


  Background & Objective: Malignant melanoma is the fatal cutaneous neoplasm which is curable by the early diagnosis. The expression of occludin protein which is an integral membrane protein is altered in an epithelial-to-mesenchymal transition. Although, recent studies provide sufficient evidence ...  Read More

58. Characterization of Immunophenotypic Aberrancies in Adult and Childhood Acute Lymphoblastic Leukemia: Lessons from Regional Variation

Mitra Rezaei; Sandra Refoua; Najme Esfandiari

Volume 15, Issue 1 , Winter 2020, , Pages 1-7


  Background & Objective:Although the antigen expression patterns of acute lymphoblastic leukemia (ALL) are well known, this study attempted to evaluate commonly used immune markers for immunophenotyping of acute leukemia to set the minimum of necessary diagnostic panels by flow cytometry.Methods:This ...  Read More

59. The Usefulness of CD10 in Distinguishing between Cutaneous Basal Cell Carcinoma and Squamous Cell Carcinoma

Shahram Sabeti; Farhad Malekzad; Nastaran Neishaboori; Mihan Pourabdollah Toutkaboni; Farahnaz Bidarizerehpoosh

Volume 9, Issue 4 , Autumn 2014, , Pages 245-250

  Background & Objectives:  CD10 is a cell surface enzyme with metalloendopeptidase activity, also known as Common Acute Lymphoblastic Leukaemia Antigen, which mainly serves as a marker for acute lymphoblastic leukemia (ALL). To date and to the best of our knowledge, only few comparative immunohistochemical ...  Read More

60. Pathologic Lesions of Liver, Kidney and Lung in the Autopsy of 100 Mustard Gas-Exposed Iranian War Veterans

Nahid Kazemzadeh; Alireza Kadkhodaei; Babak Soltani; Siamak Soltani; Sahar Rismantab Sani

Volume 9, Issue 3 , Summer 2014, , Pages 181-186

  Background & Objectives: Respiratory, central nervous system, and skin complications of mustard gas toxicity have previously been studied; however, the liver and kidney side effects due to this intoxication have not been fully noted. We aimed to evaluate the frequency of liver, kidney and lung lesions ...  Read More

61. The Effects of Vitamin E on the Liver Integrity of Mice Fed with Acrylamide Diet

Sedigheh Siahkoohi; Mortez Anvari; Mahmood Akhavan Tafti; Mohammad Hosseini-sharifabad

Volume 9, Issue 2 , Spring 2014, , Pages 89-98

    Background and Objectives: Acrylamide is a monomer which is formed in foodstuffs containing carbohydrates altered to asparagine during thermal processing. Vitamin E is a component in human diet considered as the most effective lipid-soluble antioxidant found in the biological system. It prevents ...  Read More

62. Comparison of Placental Morphology and Histopathology of Intrauterine Growth Restriction and Normal Infants

Nayereh Ghomian; Sakineh Amouian; Fatemeh Tavassoli; Taraneh Arbabzadeh

Volume 9, Issue 1 , Winter 2014, , Pages 9-16

  Background & Objective: Chronic non healing ulcers or scar undergoing malignant transformation is a rare phenomenon with an estimated incidence of 2%. Though, numerous predisposing factors have been identified, still it is rarely diagnosed and commonly mistaken for a benign condition. The objective ...  Read More

63. Diagnostic Accuracy of Frozen Section in Comparison With Fine Needle Aspiration Cytology in Thyroid Lesions – A Prospective Study

Mahesh Kumar; Ratnakar Potekar; Balasaheb Ramling Yelikar; Vijayalaxmi Patil; Mahesh Karigoudar; Pankaj Pande

Volume 8, Issue 4 , Autumn 2013, , Pages 219-226

  Background and Objectives: Thyroid gland because of its superficial location is amenable to direct physical examination. Clinical assessment of thyroid lesions by means of physical examination, thyroid scans and ultrasonography is not completely reliable. Fine needle aspiration cytology (FNAC) is the ...  Read More

64. Correlation of ER, PR, HER- 2 and P53 Immunoreactions with Clinico-Pathological Features in Breast Cancer

Alireza Abdollahi; Sara Sheikhbahaei; Somaye Safinejad; Issa Jahanzad

Volume 8, Issue 3 , Summer 2013, , Pages 147-152

    Background and Objectives: The most prevalent malignancy among women is known to be breast cancer (BC). Several factors contribute to determining tumor prognosis and treatment strategies. In this study, the frequency and relevance of these factors are discussed. Materials and Methods: This cross-sectional ...  Read More

65. Liver Damage and Mortality in a Male Lewis Rat of Experimental Autoimmune Encephalomyelitis

Ameneh Ghaffarinia; Cyrus Jalili; Ali Mostafaie; Shahram Parvaneh; Nafiseh Pakravan

Volume 10, Issue 1 , Winter 2015, , Pages 9-16


  Background and Objectives: Multiple sclerosis is an inflammatory disease of the central nervous system. This is due to migration of peripherally activated lymphocytes to central nervous system leading to inflammatory lesions. However, liver has an anti-inflammatory microenvironment. Myelin expression ...  Read More

66. Sero-prevelance of Cytomegalovirus and Toxoplasma Infections among Newly Diagnosed HIV Patients in Iran; Assessing the Correlation with CD4+ Cell Counts

Alireza Abdollahi; Saeed Shoar; Sara Sheikhbahaei; Siroos Jafari

Volume 8, Issue 2 , Spring 2013, , Pages 81-88

  Background and Objective: Opportunistic infections are the leading cause of death among patients subjected to the human immunodeficiency virus (HIV) infection and acquired immune deficiency syndrome (AIDS). The aim of this study was to compare the seroprevalence of Cytomegalovirus (CMV)  and toxoplasmosis ...  Read More

67. Effects of Resistance Training on Serum Cortisol and Dehydroepiandrosterone Levels in Trained Young Women

Hamid Agha-Alinejad; Mohammad-Ali Kohanpour; Suzan Sanavi; Soghra Sojudi; Gholam-Reza Behrouzi; Mona Mirsepasi

Volume 8, Issue 1 , Winter 2013, , Pages 9-16

  Background & Objectives:Endocrine hormones, through their anabolic or catabolic function, contribute in body homeostasis. They can be used to assess the physical performance in athletes. This study was performed to determine the resistance training (RT) influences on serum cortisol and dehydroepiandrosterone ...  Read More

68. Immunohistochemical Expression of p53 and bcl2 in Colorectal Adenomas and Carcinomas Using Automated Cellular Imaging System

Ban Qasim; Husam Ali; Alaa Hussein

Volume 7, Issue 4 , Summer 2012, , Pages 215-223

  Background & Objective: The current approaches to reduce the risk of colorectal carcinoma are through the detection and removal of the precursor lesion” adenomatous polyps”. The study was conducted to evaluate the immunohistochemical expression of p53 and bcl2 in colorectal adenomas and ...  Read More

69. Cytokeratin 20 in Transitional Cell Carcinoma of Bladder and Its Relation with Prognostic Factors

Mohammad Hossein Ghaini; Shaghayegh Sadat Esmailnejad; Ali Davati

Volume 7, Issue 3 , Summer 2012, , Pages 145-150

  Background and Aims: Immunohistochemical tests are one of the most important tests, which are under study to determine the prognosis of the cancers such as transitional cell carcinoma. By the time, flexible cystoscopy and urine cytology are the routine tests for following up the patients with transitional ...  Read More

70. Cytomorphological Patterns of Nodular Lesions of Liver

Alpana Banerjee; Rajesh Singh Laishram; Ahongshangbam Meina Singh; Moirangthem Kulachandra Singh; Durlav Chandra Sharma

Volume 7, Issue 2 , Spring 2012, , Pages 70-79

  Background and Objectives: Nodular lesions of liver are usually neoplastic (primary or metastatic), although inflammatory lesions can occur. The objectives of this paper were to study the cytomorphological changes in various nodular lesions of liver and to correlate the cytomorphological findings with ...  Read More

71. Accuracy of Frozen Sections

Fariba Abbasi; Zahra Yekta; Adel Aryan

Volume 7, Issue 1 , Winter 2012, , Pages 3-8

  Background and Objective: Intraoperative consultation by frozen section is a high – risk procedure with important consequences. Therefore, it is critical to determine efficiency of frozen section performance periodically. This study was performed to determine the accuracy of frozen section in Urmia ...  Read More

72. Gene Expression under F8 Promoter Driving In Mouse Hepatoma Cells: A Step towards Gene Therapy of Hemophilia
Volume 6, Issue 4 , Summer 2011, , Pages 173-178

  Background and Objectives: Significant progress has been made in treatment of hemophilia. Ex-vivo gene therapy is going popular due to the capability of this method in using isogenic cells for genetic manipulation and reintroducing them into same host after proliferation. Most gene therapy techniques ...  Read More

73. Association between Human Papillomavirus Infection and Risk of Prostate Cancer

Mohammad Banifazl; Amitis Ramezani; Ali Eslamifar; Arezoo Aghakhani

Volume 6, Issue 1 , Winter 2011, , Pages 3-7

    Human papillomavirus (HPV) is one of the most common causes of sexually transmitted diseases worldwide and is the etiological agent of cervical and other anogenital malignancies. Since HPVs have been shown to possess oncogenic potential, an association between HPV infection and prostatic cancer ...  Read More

74. Comparison of 5FU-base Chemoradiation with and without Eloxatin on Pathologic Complete Response in Neoadjuvant Chemoradiation of Rectal cancer

Ali Yaghoubi; Payam Azadeh; KhosroM M Sheibani; Mohammad Foudazi; Behrouz Shafaghi; Manouchehr Davaei

Volume 6, Issue 3 , Spring 2011, , Pages 110-116

    Background and Objectives: To compare pathologic complete response (pCR) in patients with advanced rectal cancer receiving neoadjuvant chemoradiotherapy (NACT) by 5-FU or Xeloda (capecitabine) with and without Eloxatin (oxaloplatin injection). Materials and Methods: Seventy-five consecutive ...  Read More

75. C3 and C4 Complement Levels in Iron Deficiency Anemia

Mohammad Reza Keramati; Mohammad Hadi Sadeghian; Hossein Ayatollahi; Houshang Rafatpanah; Mohammad Khajeh Daluei; Nafise Baesi

Volume 6, Issue 2 , Spring 2011, , Pages 56-62

  Background and Objectives: Complement proteins are some of the most important plasma proteins of the innate immune system. Impaired immune function is reported in subjects who are iron deficient, and there are documents that these patients are prone to infection. This study was conducted to show whether ...  Read More