Volume 15 (2020)
Volume 14 (2019)
Volume 13 (2018)
Volume 12 (2017)
Volume 11 (2016)
Volume 10 (2015)
Volume 9 (2014)
Volume 8 (2013)
Volume 7 (2012)
Volume 6 (2011)
Volume 5 (2010)
Volume 4 (2009)
Volume 3 (2008)
Volume 2 (2007)
Volume 1 (2006)
26. Chromosomal Analysis Of Couples With Bad Obstetric Histoty

Ali Mohamad Malekasgar; Mohamad Esmaeil Motlagh; Mahmood Hashemi Tabar; Mohamad Ali Ghafari

Volume 1, Issue 3 , Spring 2006, , Pages 91-98

  Background and Objective: Pregnancy termination and recurrent abortion are one of the common complications during pregnancy and in patients with a bad obstetric history. Materials and Methods: In this study, a total of 154 individuals including 75 couples four single women from different communities ...  Read More

27. Morphological Changes in Hippocampal Ca1 Area in Diabetic Rats: A Golgi-impregnation Study

Mehrdad Roghani; Mohammad Taghi Joghataie; Mohammad Reza Jalali Nadoushan; Tourandokht Baluchnejadmojarad; Farshad Roghani Dehkordi

Volume 1, Issue 4 , Summer 2006, , Pages 135-140

  Background and Objective: Although diabetes mellitus is known to be one of the risk factors for dementia but neuropathic changes in the brain of diabetic patients have not been completely revealed. Therefore, this research study was done to evaluate structural changes in pyramidal neurons of hippocampal ...  Read More

28. A Practical Guide to Differential Diagnosis of Small B Cell Lymphomas

Mehdi Nassiri

Volume 2, Issue 1 , Winter 2007, , Pages 1-6

  Correct diagnosis and classification of lymphoid neoplasms depends on the integration of morphologic, immunophenotypic and molecular genetic features. The mature small B cell lymphomas despite their overlapping histomorphologies, have different clinical behavior and treatment. In this review, differential ...  Read More

29. Deprenyl Can Mediate Neuronal Protection Rather than Neuronal Rescue

Marjan Heshmati; Hesam Amini

Volume 2, Issue 2 , Spring 2007, , Pages 45-48

  Background and Objective: Deprenyl is a drug for the treatment of Parkinson’s disease, where the dopaminergic neurons are the target of this drug. Several reports also documented that deprenyl has an effect on the sensory and motor neurons. There are some reports about the mode of action of deprenyl ...  Read More

30. Time Course of Axotomy-induced Changes in Synaptophysin Pattern and Synaptic Reaction of Spinal Motoneurons in Adult Rat

Alireza Azizzadeh Delshad; Taki Tiraihi

Volume 2, Issue 3 , Spring 2007, , Pages 83-88

  Background and Objective: Evaluation of degenerative changes of motoneurons and their related synapses can be useful in understanding the mechanisms of neurodegenerative diseases and their potential treatment. The present electron microscopic and immunohistochemical study investigates the axotomy-induced ...  Read More

31. Tumorogensis : The Dual Role of Telomerase

Joharia azhar

Volume 4, Issue 2 , Spring 2009, , Pages 51-58

    Carcinogenesis is a multistep process characterized by the gradual accumulation of genetic changes that ultimately lead to cancer. These genetic mutations can impart limitless replicative potential to the cancer cells making them immortal. Telomeres are repeat nucleotide sequence TTAGGG that ...  Read More

32. Association between Helicobacter pylori Infection and Atherosclerotic Coronary Artery Disease

Nehzat Akiash; Younes Nozari; Naser EbrahimiDaryani; Alireza Abdollahi

Volume 4, Issue 1 , Winter 2009, , Pages 1-4

    Background and Objectives: Cardiovascular disease is the most common cause of death in developed countries. In addition to traditional risk factors for cardiovascular disease, nowadays, accumulating evidence indicates that a variety of infections contribute to pathogenesis of atherosclerosis, ...  Read More

33. Is “Basal-like” Carcinoma of the Breast a Distinct Clinicopathologic Entity? A Critical Review with Cautionary Notes

Farid Moinfar

Volume 2, Issue 4 , Summer 2007, , Pages 127-143

  This review deals with studies that have used cDNA microarrays and immunohistochemistry to identify a subtype of breast carcinoma recently known as “basal-like” carcinoma. The key breast carcinoma studies are critically discussed to highlight methodological problems in cohort selection, definitions, ...  Read More

34. An Efficient Method For DNA Extraction From Paraffin Wax Embedded Tissues For PCR Amplification Of Human And Viral DNA

R, Salehi; B. Tabanifar; E. Asgarani; M. Faghihi; T. Allame

Volume 3, Issue 4 , Summer 2008, , Pages 173-178

    Background and Objective: Formalin-fixed paraffin-embedded tissues are a valuable source of DNA for molecular studies. We designed and optimized an efficient procedure for DNA extraction from formalin-fixed paraffin embedded tissues. Materials and Methods: Seventy three blocks of cervical paraffin-embedded ...  Read More

35. Remodeling Of Average Of Patients QC Method To Maximize Lengths Of Analytical Runs In Regional Reference Laboratories

Peyman Mohammadi Torbati; Hamid Seyed Javadi

Volume 3, Issue 3 , Spring 2008, , Pages 113-118

    Background and Objective: Improved and modified automation will require the development of smart process control systems that provide on-line decisions to release patients’ test results based on high analytical quality assurance formula. Materials and Methods: We collected patients’ ...  Read More

36. Association Of Maternal Hypothyroidism With Pre-eclampsia

Nahid Mostaghel; Elham Tavanayanfar; Elham Neisani Samani

Volume 3, Issue 2 , Winter 2008, , Pages 51-54

    Background and Objective: Hypertensive disorders complicating pregnancy are common and from one of the deadly triad, along with hemorrhage and infection that contribute greatly to prenatal and maternal morbidity and mortality in the developing countries. This study was designed to investigate ...  Read More

37. Volumetric Study Of Dentate Gyrus And CA3 Region In Hippocampus Of Streptozotocin-Induced Diabetic Rats: Effect Of Insulin And Ascorbic Acid

Shahriar Ahmadpour; Hossein Haghir; Yousef Sadeghi

Volume 3, Issue 1 , Winter 2008, , Pages 1-4

    Background and Objectives: Hippocampal volume reduction has been reported in diabetes mellitus type 1. It is believed that hyperglycemia and oxidative stress mediate neuropathological changes in hippocampal neurons. In this study we aimed to study the effect of insulin and an antioxidant like ...  Read More

38. Fibrogenesis: Mechanisms, Dynamics and Clinical Implications

Mark Daniel Wilson

Volume 10, Issue 2 , Spring 2015, , Pages 83-88


  Fibrosis is the pathological condition resulting in the growth of excess fibrous connective tissue in an organ or body system as a reparative or reactive process. In the field of clinical pathology, clinicians and medical scientists are endeavoring to translate experimental knowledge into effective, ...  Read More

39. The Spindle Cell Neoplasms of the Oral Cavity

Thorakkal Shamim

Volume 10, Issue 3 , Summer 2015, , Pages 175-184


  Spindle cell neoplasms are defined as neoplasms that consist of spindle-shaped cells in the histopathology. Spindle cell neoplasms can affect the oral cavity. In the oral cavity, the origin of the spindle cell neoplasms may be traced to epithelial, mesenchymal and odontogenic components. This article ...  Read More

40. Are Osteopontin and Ki67 Expressions Different in Various Histologic Grades of Meningioma? An Iranian Experience

Forough Hashemi; Pegah Babaheidarian; Soheila Dabiran

Volume 10, Issue 4 , Autumn 2015, , Pages 253-257


  Background: Meningioma is among the most common slow growing central nervous neoplasms, which recurs locally despite the benign histologic features. The aim of this study was to evaluate osteopontin and ki67 expressions in different histologic grades of meningioma in a group of Iranian people. Methods: ...  Read More

41. Thyroid Papillary Microcarcinoma: Etiology, Clinical Manifestations, Diagnosis, Follow-up, Histopathology and Prognosis

Shiva Dideban; Alireza Abdollahi; Alipasha Meysamie; Shokouh Sedghi; Mona Shahriari

Volume 11, Issue 1 , Winter 2016, , Pages 1-19

  Background: Thyroid carcinoma is the most common malignancy of the endocrine system. Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer, accounting for 70–90% of well-differentiated thyroid malignancies. Thyroid papillary microcarcinoma is a subtype of papillary carcinoma ...  Read More

Biology & Genetic
42. The Diagnosis of HIV Infection in Infants and Children

Alireza Abdollahi; Hana Saffar

Volume 11, Issue 2 , Spring 2016, , Pages 89-96

  It is estimated that the number of HIV infected children globally has increased from 1.6 million in 2001 to 3.3 million in 2012. The number of children below 15 years of age living with HIV has increased worldwide. Published data from recent studies confirmed dramatic survival benefit for infants started ...  Read More

43. Role of Immunohistochemistry in the Diagnosis of Solitary Fibrous Tumor, a Review

Bita Geramizadeh; Mahsa Marzban; Andrew Churg

Volume 11, Issue 3 , Summer 2016, , Pages 195-203

  Background: Solitary fibrous tumor (SFT) is a mesenchymal tumor which is most commonly seen in the pleura; however it can be seen in other organs such as the meninge, gastrointestinal tract, soft tissue, bone, and skin. SFT should be differentiated from other mesenchymal tumors in these organs. Immunohistochemistry ...  Read More

44. Pre-Cancerous Lesions in the Oral and Maxillofacial Region: A Literature Review with Special Focus on Etiopathogenesis

Soussan Irani

Volume 11, Issue 4 , Autumn 2016, , Pages 303-322

  Many types of cancers develop in the oral and maxillofacial region. Squamous cell carcinoma is the most common cancer and constitutes over 90 percent of these tumors. Malignant transformation is a genetic process, which later makes a phenotyping change at the cellular level. Some cancers such as oral ...  Read More

45. Cutaneous Metaplastic Synovial Cyst: A Case Report

Mina Majdi; Hana Saffar; Alireza Ghanadan

Volume 11, Issue 5 , Autumn 2016, , Pages 423-426

  Cutaneous metaplastic synovial cyst (CMSC), presents as a solitary, tender subcutaneous nodule that usually occurs at the site of previous surgery or trauma. Histologically, the lesion is characterized by a cystic structure with villous-like projections that lined by metaplastic synovial tissue. The ...  Read More

46. Malignant Colorectal Polyps; Pathological Consideration (A review)

Bita Geramizadeh; Mahsa Marzban; David Owen

Volume 12, Issue 1 , Winter 2017, , Pages 1-8

  Background: Routine screening colonoscopy is on the rise and pathologists have to deal with the ever larger numbers of excised colonic polyps. It is very important to optimize the patients’ individual treatment and further surveillance. Pathologists play a critical role in management, as most of ...  Read More

47. External Dacryocystorhinostomy; Success Rate and Causes of Failure in Endoscopic and Pathologic Evaluations

Hassan Ghasemi; Sajedeh Asghari Asl; Mohammad Ebrahim Yarmohammadi; Farhd Jafari; Pupak Izadi

Volume 12, Issue 3 , Summer 2017, , Pages 189-194

  Background and Objectives: External dacryocystorhinostomy (DCR) is the method of choice to treat nasolacrimal duct (NLD) obstruction and the other approaches are compared with it, with a failure rate of 4% to 13%. The current study aimed to assess the causes of failure in external DCR by postoperative ...  Read More

48. The Relationship between Cytokeratins 7 and 20 Expression, and Prognostic Factors in Colon Adenocarcinoma: An Immunohistochemical Study

Mohammad Hossein Gheini; Noushin Jalayer Naderi

Volume 12, Issue 2 , Spring 2017, , Pages 94-98

  Background & Objective: The role of synchronized expression pattern of cytokeratin (CK) 7 and CK20 in the prognosis of colon adenocarcinoma is unclear. The current study aimed at determining the relationship between the expression of cytokeratins 7 and 20 and prognostic factors in colon adenocarcinoma. ...  Read More

49. Herpes Simplex Virus and Langerhans Cell Histiocytosis

Maliheh Khoddami; Seyed Alireza Nadji; Paria Dehghanian

Volume 12, Issue 4 , Autumn 2017, , Pages 323-328

  Background and objective: Langerhans cell histiocytosis (LCH) is a rare histiocytic proliferative disorder of unknown etiology and mainly affects young children. The histological feature is granuloma-like proliferation of langerhans-type dendritic cells. Although the possible role of viruses such ...  Read More

50. Prevalence of Clinically Isolated Metallo-beta-lactamase-producing Pseudomonas aeruginosa, Coding Genes, and Possible Risk Factors in Iran

Abdolmajid Ghasemian; Kobra Salimian Rizi; Hassan Rajabi Vardanjani; Farshad Nojoomi

Volume 13, Issue 1 , Winter 2018, , Pages 1-9


  Background & Objective: The spread of carbapenem-resistant Pseudomonas aeruginosa is a global concern. Metallo-beta-lactamase (MBL) enzymes cause extensive drug resistance among Gram-negative bacteria. The current study aimed at determining the prevalence of MBL-producing P. aeruginosa in Iran. Methods: ...  Read More