Volume 19 (2024)
Volume 18 (2023)
Volume 17 (2022)
Volume 16 (2021)
Volume 15 (2020)
Volume 14 (2019)
Volume 13 (2018)
Volume 12 (2017)
Volume 11 (2016)
Volume 10 (2015)
Volume 9 (2014)
Volume 8 (2013)
Volume 7 (2012)
Volume 6 (2011)
Volume 5 (2010)
Volume 4 (2009)
Volume 3 (2008)
Volume 2 (2007)
Volume 1 (2006)
Biology & Genetic
Differentiating and Categorizing of Liposarcoma and Synovial Sarcoma Neoplasms by Fluorescence in Situ Hybridization

Farhad Shahi; Razieh Alishahi; Hossein Pashaiefar; Isa Jahanzad; Naser Kamalian; Ardeshir Ghavamzadeh; Marjan Yaghmaie

Volume 12, Issue 3 , July 2017, , Pages 209-217

https://doi.org/10.30699/ijp.2017.25043

Abstract
  Background & Objective: Soft tissue sarcomas (STS) constitute an uncommon and heterogeneous group of tumors of mesenchymal origin and various cytogenetic abnormalities ranging from distinct genomic rearrangements, such as chromosomal translocations and amplifications, to more intricate rearrangements ...  Read More

Microbiology
Polymorphism of IL-28B Gene (rs12979860) in HCV Genotype 1 Patients Treated by Pegylated Interferon and Ribavirin

Fahimeh Safarnezhad Tameshkel; Mohmmad Hadi Karbalaie Niya; Masuodreza Sohrabi; Mahshid Panahi; Farhad Zamani; Farid Imanzade; Nasser Rakhshani

Volume 11, Issue 3 , July 2016, , Pages 216-221

Abstract
  Background: Nowadays, the immune response to hepatitis C (HCV) treatment has become a crucial issue mostly due to the interleukin 28B (IL-28B) polymorphism effects in chronic HCV patients. The aim of this study was to detect the polymorphism of IL-28B gene (rs12979860) in HCV genotype 1 patients treated ...  Read More

Immunofluorescence Pattern of Autoimmune Bullous Diseases in Iranian Patients

Alireza Monsef; Mahmood Farshchian; Mohammad Jafari; Mehdi Farshchian

Volume 7, Issue 4 , September 2012, , Pages 231-235

Abstract
  Background & Objective: Autoimmune bullous diseases are associated with autoimmunity against structural components in the skin and mucous membranes. Autoantibodies are against the intercellular junctions in pemphigus disease and hemidesmosomal unchoring complex in pemphigiod diseases and epidermolysis ...  Read More

Role of Cyclooxygenese-2 (COX-2) Expression in Breast Cancer Differentiation and Its Relationship with Hormone Receptors Status

Farahnaz Ghahremanfard; Jafar Alavy Toussy; Behrang Kazeminezhad; Farzaneh Ramezani

Volume 8, Issue 4 , October 2013, , Pages 235-240

Abstract
  Background and Objectives: Cyclooxygenese-2 (COX-2) expression in breast cancer and its correlation with tumor prognosis is unclear. We investigated the incidence of COX-2 expression in patients and assessed interactions between COX-2 and clinical features of cancer and expression of HER2/neu, estrogen ...  Read More

Detection of icaABCD Genes and Biofilm Formation in Clinical Isolates of Methicillin Resistant Staphylococcus aureus

Mohsen Mirzaee; Shahin Najar Peerayeh; Abdol-Majid Ghasemian

Volume 9, Issue 4 , October 2014, , Pages 257-262

Abstract
  Background & Objectives:  Methicillin resistance Staphylococcus aureus (MRSA) is one of the most important pathogens that causes several nosocomial and community infections. Adhesion to surfaces and biofilm formation is considered main step in staphylococcal infection. The aims of this study ...  Read More

Hematopathology
Hematocytological Clues of Peripheral Blood in Different Clinical Presentations of COVID-19

Fakhri Mohaghegh Zahed; Shahriar Dabiri; Abdolreza Javadi; Sajjadeh Movahedinia; Manzumeh Shamsi Meymandi Pharm; Bahram Dabiri; Parisa khorasani Esmaili; Mitra Sadat Rezaei; Mehrdad Farokhniya

Volume 18, Issue 3 , July 2023, , Pages 270-278

https://doi.org/10.30699/ijp.2023.561331.2963

Abstract
  Background: To gain insight into the pathogenesis and clinical course of COVID-19 from a historical perspective, we reviewed paraclinical diagnostic tools of this disease and prioritized the patients with a more severe form of disease admitted to intensive care units (ICUs). The objective was to better ...  Read More

Uropathology
Protective Effects of Hydrocortisone, Vitamin C and E Alone or in Combination against Renal Ischemia-Reperfusion Injury in Rat

Omid Azari; Reza Kheirandish; Mohammad Farajli Abbasi; Shahin Ghahramani Gareh Chaman; Masoud Bidi

Volume 10, Issue 4 , October 2015, , Pages 272-280

https://doi.org/10.7508/ijp.2015.04.004

Abstract
  Background: Renal ischemia reperfusion injury may occur in a variety of clinical situations, following a transient drop in total or regional blood flow to the kidney. This study was performed to investigate the protective effects of different antioxidants such as vitamin C, vitamin E, hydrocortisone ...  Read More

Molecular Pathology
Investigation of HER-2 expression and its Correlation with clinicopathological parameters and overall survival of esophageal squamous cell carcinoma patients

Mitra Heidarpour; Mehran Taheri; Ali Akhavan; Parvin Goli; Amirhosein Kefayat

Volume 15, Issue 4 , October 2020, , Pages 274-281

https://doi.org/10.30699/ijp.2020.113829.2235

Abstract
  Background & Objective: Human epidermal growth factor receptor 2 (HER-2) exhibits a vast range of expression in esophageal squamous cell carcinoma (ESCC) patients as a biomarker. This paper aimed to investigate HER-2 expression and clinicopathological parameters of esophageal SCC. Methods: HER-2 ...  Read More

Endocrine Pathology
Promoter Methylation of Four Tumor Suppressor Genes in Human Papillary Thyroid Carcinoma

Fatemeh Khatami; Bagher Larijani; Ramin Heshmat; Shirzad Nasiri; Hiva Saffar; Gita Shafiee; Azam Mossafa; Seyed Mohammad Tavangar

Volume 14, Issue 4 , October 2019, , Pages 290-298

https://doi.org/10.30699/ijp.2019.94401.1922

Abstract
  Background & Objective: Papillary thyroid cancer (PTC) is considered to be the most common type of thyroid malignancies. Epigenetic alteration, in which the chromatin conformation and gene expression change without changing the sequence of DNA, can occur in some tumor suppressor genes and oncogenes. ...  Read More

Dermatopathology
Non-scarring Alopecias in Iranian Patients: A Histopathological Study With Hair Counts

Fatemeh Sari Aslani; Mina Heidari Esfahani; Mozhdeh Sepaskhah

Volume 13, Issue 3 , July 2018, , Pages 317-324

Abstract
  Background and Objective: Non-scarring alopecia is a challenge in the diagnosis and treatment, rarely studied in Asian countries. The current study aimed at evaluating histopathological features including hair count of different subtypes of non-scarring alopecia in Iranian patients.Methods: The current ...  Read More

Oral Pathology
Expression of Human Kallikreins 4, 8, 10, 11 and 13 in Pleomorphic Adenomas and Mucoepidermoid Carcinomas

Maryam Alsadat Hashemipour; Fatemeh Sadat Fatah; Mohammad Javad Ashraf; Mehrnaz Tahmasebi

Volume 11, Issue 4 , October 2016, , Pages 334-344

Abstract
  Background: In cancers of prostate, breast, oropharynx, lung, hypopharynx and skin, human tissue kallikreins has been demonstrated as a main role in these problems. There are many research works in which some human tissue kallikreins are expressed in salivary glands. In the present study, the main goal ...  Read More

Oral Pathology
Association of Candida sp. with the Degrees of Dysplasia and Oral Cancer: A Study by Calcofluor White under Fluorescent Microscopy

Sandhya Tamgadge; Avinash Tamgadge; Aswathy Pillai; Mayura Chande; Siddharth Acharya; Narayan Kamat

Volume 12, Issue 4 , December 2017, , Pages 348-355

https://doi.org/10.30699/ijp.2017.27991

Abstract
  Background and objective:Candida albicans (C. albicans) play a significant role in oral mucosal carcinogenesis. It can be identified using various techniques in cytological smears. But, very few studies have been conducted on histopathological sections using calcofluor white M2R under fluorescent microscopy. ...  Read More

Biology & Genetic
The Effect of Cadmium on Apoptotic Genes mRNA Expression of Bax and Bcl-2 in Small Intestine of Rats

Narjes Seid Alian; Parvin khodarahmi; Vahid Naseh

Volume 13, Issue 4 , October 2018, , Pages 408-414

Abstract
  Background: Cadmium is a potent toxicant and carcinogenic in human and experimental animals. The evidence indicates that cadmium induces aberrant gene expression, inhibition of DNA damage repair, and apoptosis. In this study, we investigated the effects of IP (intraperitoneal) injection of cadmium on ...  Read More

Oral Pathology
Odontogenic Fibroma of the Maxilla - An Atypical Presentation

Arpita Kabiraj; Anil Singh; Tanya Khaitan; Amrita Jaiswal

Volume 11, Issue 5 , October 2016, , Pages 435-438

Abstract
  Odontogenic fibroma (OF) is considered an unusual, benign mesenchymal neoplasm and one of the most little-understood lesions amongst all odontogenic neoplasms. The incidence rate of the tumor is from 0% to 5.5%. WHO classified them into intraosseous or central and extraosseous or peripheral variants. ...  Read More

Expression of the Apoptosis Inhibitor Bcl-2 in Sputum Eosinophils in Patients with Asthma

Ghasem Azimi; Hesam Amini; Niosha Andalibi

Volume 5, Issue 1 , January 2010, , Pages 18-21

Abstract
    Background and Objectives: Apoptosis of eosinophils is of significant value in assessing the airway inflammation in patients with asthma. Our purpose was to investigate the degree of expression of the Bcl-2 protein in sputum eosinophils during acute asthma exacerbation and its relationship with ...  Read More

Beta-Thalassemia Carrier Detection by NESTROFT: An Answer in Rural Scenario?

Indranil Chakrabarti; Swapan Kumar Sinha; Nilanjana Ghosh; Bidyut Krishna Goswami

Volume 7, Issue 1 , January 2012, , Pages 19-26

Abstract
  Background and Objectives: Beta-thalassemia continues to be a cause of significant burden to the society particularly in the poorer developing countries. Although sophisticated methods of screening have become available, a hunt for a cheap, rapid, objective screening method still remains elusive. Thus, ...  Read More

Helicobacter pylori cagA Status, vacA Subtypes and Histopathologic Findings in Iranian Patients with chronic gastritis

Forough Foroughi; Mahsa Molaei; Reza Mashayekhi; Hossein Dabiri; Leila Shokrzadeh; Homayoon Zojaji; Mehrdad Hagh Azali; Mohammad Reza Zali

Volume 4, Issue 1 , January 2009, , Pages 19-25

Abstract
    Background and Objective: Helicobacter pylori has several strains with different degrees of virulence. The aim of this study was to detect two major important virulence factors, cagA/vacA genotypes, and to determine correlations among different cagA/vacA genotypes and histological features of ...  Read More

The Value of Interleukin-8 and Interleukin-6 in Cervical Secretions as Predictors of Preterm Delivery

Ahia Garshasbi; Samira Behboudi Gandevani; Soghrat Faghih-Zadeh; Tooba Ghazanfari

Volume 6, Issue 1 , January 2011, , Pages 20-26

Abstract
    Background and Objective: Preterm birth occurs in 8% to 11% of all pregnancies and is responsible for 75% to 80% of all neonatal deaths. Cytokines may be involved in the etiology of preterm birth through their stimulation of prostaglandin synthesis. Cytokines may be released intocervicovaginal ...  Read More

Phenotypic Detection Of Metallo-beta-lactamase Producing Pseudomonas aeruginosa Strains Isolated From Burned Patients

Parviz Owlia; Horieh Saderi; Zohreh Karimi; Seyed Mohammad Bagher Akhavi Rad; Mohammad Ali Bahar

Volume 3, Issue 1 , January 2008, , Pages 20-25

Abstract
    Background and Objective: Metallo-beta-lactamase (MBL)-mediated resistance is an emerging threat in hospital isolates of Pseudomonas aeruginosa. There is not enough information from Iran regarding the prevalence and the screening methods for such enzymes. The present study was undertaken to detect ...  Read More

Evaluation of chromosomal changes in patients with spontaneous abortion in Khozestan province

Iran Rashidi; Javad Mohammadi Asl

Volume 1, Issue 1 , January 2006, , Pages 21-24

Abstract
  Objective: Approximately 15-20% of clinically recognizable pregnancies end in spontaneous abortion. The incidence of chromosomal abnormalities in those abortions is as high as 50%.A modest but clinically important proportion of spontaneous abortions is caused by a balanced chromosomal aberration in one ...  Read More

Clinical and Laboratory Findings Including the Diagnostic Value of the Widal Test in Pediatric Cases of Typhoid Fever in Tehran

Alireza Nateghian; Joan L. Robinson; Simin Rezaii; Mahnaz Kefayati; Naser Rakhshani; Safa Sianati

Volume 2, Issue 1 , January 2007, , Pages 23-28

Abstract
  Background and Objective: The diagnosis of typhoid fever in children is a challenge due to the non-specific clinical picture. The current role of the Widal test for diagnosis in developing countries has not been clear. Materials and Methods: Charts were reviewed on all children ≤ 15 years of age discharged ...  Read More

Biochemistry
The Insulin-like Growth Factor-1 (G>A) and 5,10-methylenetetrahydrofolate Reductase (C677T) Gene Variants and the Serum Levels of Insulin-like Growth Factor-1, Insulin, and Homeostasis Model Assessment in Patients with Acne Vulgaris

Sakineh Zinati-Saeed; Ebrahim Shakiba; Ziba Rahimi; Mona Akbari; Fariba Najafi; Fariborz Bahrehmand; Asad Vaisi-Raygani; Zohreh Rahimi; Ali Ebrahimi; Mehrali Rahimi

Volume 15, Issue 1 , January 2020, , Pages 23-29

https://doi.org/10.30699/ijp.2019.105695.2098

Abstract
  Background & Objective:To find an association between gene variants of insulin-like growth factor-1 (IGF-1) and 5,10-methylenetetrahydrofolate reductase (MTHFR) with the risk of acne vulgaris (AV).Methods:In a case-control study, we investigated 150 AV patients and 148 healthy individuals (aged 18-25 ...  Read More

Expression of Anaplastic Lymphoma Kinase Protein in Human Breast Cancer

Ali Zare Mehrjardi; Amineh Vaghefi

Volume 8, Issue 1 , January 2013, , Pages 27-35

Abstract
  Background & Objectives: Anaplastic lymphoma Kinase (ALK) is a receptor tyrosine kinase involved in the genesis of several human cancers. ALK was initially identified because of its involvement in anaplastic large cell lymphoma (ALCL). ALK is believed to foster tumorigenesis following activation ...  Read More

Tongue Squamous Cell Carcinoma: A Clinical Study

Hamidreza Azimi; Saeedeh Khajehahmadi; Amin Rahpeyma

Volume 9, Issue 1 , January 2014, , Pages 28-32

Abstract
    Background and Objectives: Squamous cell carcinoma of the tongue (SCCOT) is the most common malignant neoplasm in oral cavity. At the time of the diagnosis of SCCOT regional metastases with a high mortality rate are common, which is due to the extensive lymphatic system drainage of the tongue. ...  Read More

Molecular Pathology
Uterine Leiomyoma and Reproductive Tract Infections Detected by Polymerase Chain Reaction

Geita Saadatnia; Aboutaleb Saremi; Behrouz Salehian; Pirooz Salehian

Volume 14, Issue 1 , January 2019, , Pages 33-40

https://doi.org/10.30699/ijp.14.1.33

Abstract
  Background and Objective: For nearly a century, it has been suspected that reproductive tract infections play an etiologic role in uterine leiomyoma. However, no epidemiologic study of leiomyoma has used the polymerase chain reaction (PCR) to compare uterine tissues from cases and non-cases, and to investigate ...  Read More