Volume 19 (2024)
Volume 18 (2023)
Volume 17 (2022)
Volume 16 (2021)
Volume 15 (2020)
Volume 14 (2019)
Volume 13 (2018)
Volume 12 (2017)
Volume 11 (2016)
Volume 10 (2015)
Volume 9 (2014)
Volume 8 (2013)
Volume 7 (2012)
Volume 6 (2011)
Volume 5 (2010)
Volume 4 (2009)
Volume 3 (2008)
Volume 2 (2007)
Volume 1 (2006)
Clinical Value of Serum S100A8/A9 and CA15-3 in the Diagnosis of Breast Cancer

Samaneh Khorrami; Masoumeh Tavakoli; Elahe Safari

Volume 14, Issue 2 , April 2019, , Pages 104-112

https://doi.org/10.30699/ijp.14.2.104

Abstract
  Background and Objective: S100A8/A9 is a heterodimer calcium-binding protein which is involved in tumor cell proliferation, adhesion and invasion, and is proposed as a biomarker for better diagnosis and prognosis in many cancers. The aim of this study was to evaluate the simultaneous serum-based level ...  Read More

Asymptomatic Urinary Tract Infection in Pregnant Women

Ali Jazayeri Moghadas; Gholamreza Irajian

Volume 4, Issue 3 , June 2009, , Pages 105-108

Abstract
    Background and Objectives: Urinary tract infection is one of the most common bacterial infections in the human population, and more frequent infection during pregnancy. With notice to this point that most of urinary tract infections during pregnancy are asymptomatic, they could lead to serious ...  Read More

Comparison of 5FU-base Chemoradiation with and without Eloxatin on Pathologic Complete Response in Neoadjuvant Chemoradiation of Rectal cancer

Ali Yaghoubi; Payam Azadeh; KhosroM M Sheibani; Mohammad Foudazi; Behrouz Shafaghi; Manouchehr Davaei

Volume 6, Issue 3 , June 2011, , Pages 110-116

Abstract
    Background and Objectives: To compare pathologic complete response (pCR) in patients with advanced rectal cancer receiving neoadjuvant chemoradiotherapy (NACT) by 5-FU or Xeloda (capecitabine) with and without Eloxatin (oxaloplatin injection). Materials and Methods: Seventy-five consecutive ...  Read More

Microbiology
Development of Preventive Vaccines for Hepatitis C Virus E1/E2 Protein

Faezeh Ghasemi; Majid Ghayour Mobarhan; Hamed Gouklani; Zahra Meshkat

Volume 13, Issue 2 , April 2018, , Pages 113-124

https://doi.org/10.30699/ijp.13.2.113

Abstract
  Hepatitis C virus (HCV) is responsible for a vast majority of liver failure cases. HCV is a kind of blood disease appraised to chronically infect 3% of the worlds’ population causing significant morbidity and mortality. Therefore, a complete knowledge of humoral responses against HCV, resulting ...  Read More

Lack of Mutation in the Hot Spot Region of the Human P53 Gene in a Number of Iranian Hepatocellular Carcinoma Patients

Hamid Galehdari; Fariborz Soheili; Ali Mohammad Foroughmand; Abdolreza Masjedizadeh

Volume 5, Issue 3 , June 2010, , Pages 116-120

Abstract
    Objectives and Background: Mutation directed inactivation of the tumor suppressor gene p53 have been found incountries with high frequency for hepatocellular carcinomas (HCCs). Our goal in the present study was screening of the p53 gene in tumor tissues from HCC affected individuals in southwest ...  Read More

Seroprevalence of Human Immunodificiency Virus (HIV) and Hepatitis C Infection In Hemophilic Patients In Iran

Alireza Abdollahi; Reza Shahsiah; Mohssen Nassiri Toosi; Manije Lak; Katayoun Karimi; Mohammadreza Managhchi; Katayoun Samimi-rad

Volume 3, Issue 3 , June 2008, , Pages 119-124

Abstract
    Background and Objective: Although transfusion therapy has lead to great improvement in longevity for hemophiliacs, but there have been tragic setbacks especially from transmission of human immunodeficiency virus (HIV) and hepatitis C virus (HCV) .HIV was reported to increase the rate of HCV-related ...  Read More

Infectious Diseases
Higher Risk of Chronic Hepatitis E Virus infection in Patients with Human Immunodeficiency Virus-1: An Iranian Cross- sectional Study

Mohamad Javad Zahedi; Sara Shafieipour; Mohammad Mahdi Hayatbakhsh Abbasi; Nader Pourjamali; Mohsen Nakhaie; Javad Charostad; Mohammad Rezaei Zadeh Rukerd; Mohammad Mehdi Lashkarizadeh; Fatemeh Karami Robati; Azam Dehghani; Yunes Jahani; Seyed Mohamad Ali Arabzadeh; Hamid Reza Mollaei; Ebrahim Ranjbar

Volume 18, Issue 2 , April 2023, , Pages 125-133

https://doi.org/10.30699/ijp.2023.551657.2870

Abstract
  Background & Objective: Hepatitis E Virus (HEV) infection may be common in Human Immunodeficiency Virus (HIV-1) patients and may lead to chronic infection as well as cirrhosis. We intended to determine the incidence of HEV infection among HIV-1 patients in comparison to individuals without HIV-1 ...  Read More

A Study on the Frequency of Fungal Agents in Otitis Externa in Semnan

Farahnaz Bineshian; Gholamreza Irajian; Seyed Kaveh Koochak-Alavi; Mohammad Reza Fredonian

Volume 1, Issue 4 , September 2006, , Pages 141-144

Abstract
  Background and Objective: Otitis externa is a common condition affecting the external auditory canal. Predisposing factors implicated in the pathogenesis of the condition include preexisting aural disease, genetic factors, infection, trauma, and climatic conditions. Bacteria are the most common cause ...  Read More

Antimicrobial Susceptibility Pattern of Clinical Isolates of Pseudomonas Aeruginosa in a Pediatric Hospital

Sara Jam; Duman Sabzevari; Arezoo Aghakhani; Ali Eslamifar; Mohammad Banifazl; Amitis Ramezani

Volume 2, Issue 4 , September 2007, , Pages 144-148

Abstract
  Background and Objective: Pseudomonas aeruginosa has become a frequent cause of nosocomial infections, particularly in intensive care units (ICUs). Many reports have documented high rates of resistance in this species to commonly-used broad-spectrum antibiotics. The aim of this study was to assess the ...  Read More

Cytokeratin 20 in Transitional Cell Carcinoma of Bladder and Its Relation with Prognostic Factors

Mohammad Hossein Ghaini; Shaghayegh Sadat Esmailnejad; Ali Davati

Volume 7, Issue 3 , July 2012, , Pages 145-150

Abstract
  Background and Aims: Immunohistochemical tests are one of the most important tests, which are under study to determine the prognosis of the cancers such as transitional cell carcinoma. By the time, flexible cystoscopy and urine cytology are the routine tests for following up the patients with transitional ...  Read More

Correlation of ER, PR, HER- 2 and P53 Immunoreactions with Clinico-Pathological Features in Breast Cancer

Alireza Abdollahi; Sara Sheikhbahaei; Somaye Safinejad; Issa Jahanzad

Volume 8, Issue 3 , July 2013, , Pages 147-152

Abstract
    Background and Objectives: The most prevalent malignancy among women is known to be breast cancer (BC). Several factors contribute to determining tumor prognosis and treatment strategies. In this study, the frequency and relevance of these factors are discussed. Materials and Methods: This cross-sectional ...  Read More

In Vitro Bactericidal Activity of Encapsulated Amikacin in Liposome

Mohsen Mirzaee; Parviz Owlia; Mohammad Reza Mehrabi; Amir Gharib

Volume 4, Issue 4 , September 2009, , Pages 151-156

Abstract
  Background and Objectives:  The most common problems limiting the medical use of aminoglycosides have been the nephro- and oto-toxicities as well as the increasing bacterial resistance. Encapsulation of drugs into liposomes enhances their efficacy while reducing their toxicities. The aim of this ...  Read More

Gene Expression under F8 Promoter Driving In Mouse Hepatoma Cells: A Step towards Gene Therapy of Hemophilia
Volume 6, Issue 4 , September 2011, , Pages 173-178

Abstract
  Background and Objectives: Significant progress has been made in treatment of hemophilia. Ex-vivo gene therapy is going popular due to the capability of this method in using isogenic cells for genetic manipulation and reintroducing them into same host after proliferation. Most gene therapy techniques ...  Read More

Evaluation of Serum PSA in Different Storage Environments

Mohammad Hassan Ghosian Moghaddam; Hossin Ayatollahi; Fatemeh Ghafarirad; Maryam Maleki; Ali Davati

Volume 5, Issue 4 , September 2010, , Pages 173-177

Abstract
  Background and Objective: Prostate cancer is a prevalent disease around the world. The prostatic specific Antigen (PSA) test has recently proved itself as a useful method for the diagnosis and examination of patients with prostatic cancer. The objective of this study was to compare the stability of free ...  Read More

Correlation Between Soluble Vascular Endothelial Growth Factor A, Its Receptor 1 And Response To Chemotherapy In Acute Leukemia In Children

Mitra Mehrazma; Khadijeh Arjomandi Rafsanjani; Behzad Torkamanipoor

Volume 3, Issue 4 , September 2008, , Pages 179-182

Abstract
    Background and Objective: Vascular endothelial growth factor (VEGF) and its receptors (VEGF-R1 and R2) are major regulators of angiogenesis. This study was designed to assess serum levels of VEGF and VEGF-R1 and their prognostic significance in newly diagnosed childhood acute leukemia. Materials ...  Read More

Pathologic Lesions of Liver, Kidney and Lung in the Autopsy of 100 Mustard Gas-Exposed Iranian War Veterans

Nahid Kazemzadeh; Alireza Kadkhodaei; Babak Soltani; Siamak Soltani; Sahar Rismantab Sani

Volume 9, Issue 3 , July 2014, , Pages 181-186

Abstract
  Background & Objectives: Respiratory, central nervous system, and skin complications of mustard gas toxicity have previously been studied; however, the liver and kidney side effects due to this intoxication have not been fully noted. We aimed to evaluate the frequency of liver, kidney and lung lesions ...  Read More

The Effects of Cyclin D1 and Bcl-2 Expressıon on Aggressive Behavior in Basal Cell and Basosquamous Carcinoma

Oya N. Sivrikoz; Gülşen Kandiloğlu

Volume 10, Issue 3 , July 2015, , Pages 185-191

https://doi.org/10.7508/ijp.2015.03.002

Abstract
  Background and Objective: Clinical behavior of basal cell carcinoma (BCC) is known to be different according to histological growth pattern and basosquamous cell carcinomas (BSC) are known with their aggressive behavior and metastatic capacity. In this study, we evaluated bcl-2 and cyclin D1 expressions ...  Read More

Dermatopathology
Evaluation of Immunohistochemical Findings and Clinical Features associated with Local Aggressiveness in Basal Cell Carcinoma

Simin Shamsi meymandi; Shahriar Dabiri; Alireza ZeynadiniMeymand; Maryam Iranpour; Maryam Khalili; Sorour Alijani; Mahin Aflatoonian

Volume 14, Issue 3 , August 2019, , Pages 193-196

https://doi.org/10.30699/ijp.2019.82907.1781

Abstract
  Background & Objective:Basal cell carcinoma (BCC) is classified into BCC1 or low risk (nodular, superficial type) and BCC2 or high risk (micronodular, morpheaform, infiltrative, and basosquamous types) based on clinical behavior. This study attempts to evaluate immunohistochemical (IHC) findings ...  Read More

The diagnostic value of TTF1, P63, HMWK [34βE12], CK7, and CD56 immunostaining in classification of lung carcinoma

Amir Hossein Jafarian; Masoumeh Gharib; Nema Mohammadian Roshan; Samaneh Sherafatnia; Abbas Ali Omidi; Sahar Bagheri

Volume 12, Issue 3 , July 2017, , Pages 195-201

https://doi.org/10.30699/ijp.2017.25041

Abstract
  Background & objective: The histologic distinction of small cell from non-small cell lung carcinoma and correct identification of all subtypes of lung carcinoma are very important in treatment management. The main method for histologic classification of lung tumors is based on morphology. However, ...  Read More

Evaluation of Aryoseven Safety (Recombinant Activated Factor VII) in Patients with Bleeding Disorders (An Observational Post-Marketing Surveillance Study)

Gholamreza Toogeh; Hassan Abolghasemi; Peyman Eshghi; Mohammadreza Managhchi; Mohammadreza Shaverdi-niasari; Katayoon Karimi; Samin Roostaei; Neda Emran; Alireza Abdollahi

Volume 11, Issue 3 , July 2016, , Pages 204-209

Abstract
  Background: Recombinant activated factor VII induces hemostasis in patients with coagulopathy disorders. AryoSeven™ as a safe Iranian Recombinant activated factor VII has been available on our market. This study was performed to establish the safety of AryoSeven on patients with coagulopathy disorder. ...  Read More

Immunohistochemical Expression of p53 and bcl2 in Colorectal Adenomas and Carcinomas Using Automated Cellular Imaging System

Ban Qasim; Husam Ali; Alaa Hussein

Volume 7, Issue 4 , September 2012, , Pages 215-223

Abstract
  Background & Objective: The current approaches to reduce the risk of colorectal carcinoma are through the detection and removal of the precursor lesion” adenomatous polyps”. The study was conducted to evaluate the immunohistochemical expression of p53 and bcl2 in colorectal adenomas and ...  Read More

Diagnostic Accuracy of Frozen Section in Comparison With Fine Needle Aspiration Cytology in Thyroid Lesions – A Prospective Study

Mahesh Kumar; Ratnakar Potekar; Balasaheb Ramling Yelikar; Vijayalaxmi Patil; Mahesh Karigoudar; Pankaj Pande

Volume 8, Issue 4 , October 2013, , Pages 219-226

Abstract
  Background and Objectives: Thyroid gland because of its superficial location is amenable to direct physical examination. Clinical assessment of thyroid lesions by means of physical examination, thyroid scans and ultrasonography is not completely reliable. Fine needle aspiration cytology (FNAC) is the ...  Read More

Infectious Diseases
Molecular Diagnosis of COVID-19; Biosafety and Pre-analytical Recommendations

Mohammad Vasei; Elham Jafari; Vahid Falah Azad; Moeinadin Safavi; Maryam Sotoudeh

Volume 18, Issue 3 , July 2023, , Pages 244-256

https://doi.org/10.30699/ijp.2023.1988405.3061

Abstract
  From the beginning of the COVID-19 epidemic, clinical laboratories around the world have been involved with tests for detection of SARS-CoV-2. Currently, RT-PCR (real-time reverse transcription polymerase chain reaction assay) is the gold standard for identifying the virus. Many factors are involved ...  Read More

The Usefulness of CD10 in Distinguishing between Cutaneous Basal Cell Carcinoma and Squamous Cell Carcinoma

Shahram Sabeti; Farhad Malekzad; Nastaran Neishaboori; Mihan Pourabdollah Toutkaboni; Farahnaz Bidarizerehpoosh

Volume 9, Issue 4 , October 2014, , Pages 245-250

Abstract
  Background & Objectives:  CD10 is a cell surface enzyme with metalloendopeptidase activity, also known as Common Acute Lymphoblastic Leukaemia Antigen, which mainly serves as a marker for acute lymphoblastic leukemia (ALL). To date and to the best of our knowledge, only few comparative immunohistochemical ...  Read More

Microbiology
The Microbial Surface Components Recognizing Adhesive Matrix Molecules (MSCRAMMs) Genes among Clinical Isolates of Staphylococcus aureus from Hospitalized Children

Abdolmajid Ghasemian; Shahin Najar Peerayeh; Bita Bakhshi; Mohsen Mirzaee

Volume 10, Issue 4 , October 2015, , Pages 258-264

https://doi.org/10.7508/ijp.2015.04.002

Abstract
  Background:Isolates of Staphylococcus aureus express a myriad of adhesive surface proteins that play important role in colonization of the bacteria on nasal and skin surfaces, beginning the process of pathogenesis. The aim of this study was to screen several of the Microbial Surface Components Recognizing ...  Read More